Schering-Plough Corporation was an American pharmaceutical company. It was originally the U.S.
subsidiary
A subsidiary, subsidiary company or daughter company is a company owned or controlled by another company, which is called the parent company or holding company. Two or more subsidiaries that either belong to the same parent company or having a s ...
of the German company
Schering AG
Schering AG was a research-centered German multinational pharmaceutical company headquartered in Wedding, Berlin, which operated as an independent company from 1851 to 2006. In 2006, it was bought by Bayer AG and merged to form the Bayer subs ...
, which was founded in 1851 by
Ernst Christian Friedrich Schering
Ernst Christian Friedrich Schering (31 May 1824 – 27 December 1889) was a German apothecary and industrialist who created the Schering Corporation. The company split into Schering AG and Schering-Plough after US assets were seized during W ...
. As a result of
nationalization
Nationalization (nationalisation in British English) is the process of transforming privately-owned assets into public assets by bringing them under the public ownership of a national government or state. Nationalization usually refers to pri ...
, it became an independent company. In 1971, the Schering Corporation merged with Plough (founded by Memphis area entrepreneur Abe Plough in 1908)
["Abe Plough (1892-1984)](_blank)
," ''Tennessee Encyclopedia of History and Culture,'' online. to form Schering-Plough. On November 4, 2009
Merck & Co. merged with Schering-Plough with the new company taking the name of Merck & Co.
Schering-Plough manufactured several pharmaceutical
drugs
A drug is any chemical substance that causes a change in an organism's physiology or psychology when consumed. Drugs are typically distinguished from food and substances that provide nutritional support. Consumption of drugs can be via inhalat ...
, the most well-known of which were the
allergy
Allergies, also known as allergic diseases, refer a number of conditions caused by the hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include hay fever, food allergies, atopic derma ...
drugs
Claritin
Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. This includes allergic rhinitis (hay fever) and hives. It is also available in combination with pseudoephedrine, a decongestant, known as lo ...
and
Clarinex
Desloratadine (trade names Clarinex and Aerius) is a tricyclic H1 inverse agonist that is used to treat allergies. It is an active metabolite of loratadine.
It was patented in 1984 and came into medical use in 2001.
Medical uses
Desloratad ...
, an anti-
cholesterol
Cholesterol is any of a class of certain organic molecules called lipids. It is a sterol (or modified steroid), a type of lipid. Cholesterol is biosynthesized by all animal cells and is an essential structural component of animal cell mem ...
drug
Vytorin
Ezetimibe/simvastatin is a drug combination used for the treatment of dyslipidemia. It is a combination of ezetimibe (known as Zetia in the United States) and the statin drug simvastatin (known as Zocor in the US).
Ezetimibe reduces blood choles ...
, and a
brain tumor
A brain tumor occurs when abnormal cells form within the brain. There are two main types of tumors: malignant tumors and benign (non-cancerous) tumors. These can be further classified as primary tumors, which start within the brain, and seconda ...
drug
Temodar
Temozolomide (TMZ), sold under the brand name Temodar among others, is a medication used to treat brain tumors such as glioblastoma and anaplastic astrocytoma. Text was copied from this source which is © European Medicines Agency. Reproduction i ...
. These are now available from Merck & Co.
Schering-Plough also owned and operated the major foot care brand name
Dr. Scholl's
Dr. Scholl's is a footwear and orthopedic foot care brand originating in the United States, marketed in some countries as simply Scholl. Since 2021, global rights to the brand have been owned by investment firm Yellow Wood Partners through su ...
and the skin care line
Coppertone
Coppertone is the brand name for an American sunscreen. Coppertone is headquartered in Whippany, New Jersey. Coppertone uses a variety of branding, including the Coppertone girl logo and a distinctive fragrance.
Product line
The original prod ...
. These also became a part of the new company.
, Schering-Plough had 1.4% market share in the U.S., placing it seventeenth in the top twenty pharmaceutical corporations by sales compiled by
IMS Health
IMS Health was an American company that provided information, services and technology for the healthcare industry. IMS stood for Intercontinental Medical Statistics. It was the largest vendor of U.S. physician prescribing data. IMS Health was fo ...
.
Schering-Plough was a full member of the
(EFPIA), a membership which is also maintained by the new Merck & Co.
History
Pharmaceuticals and consumer products
Schering was founded in 1851 by
Ernst Christian Friedrich Schering
Ernst Christian Friedrich Schering (31 May 1824 – 27 December 1889) was a German apothecary and industrialist who created the Schering Corporation. The company split into Schering AG and Schering-Plough after US assets were seized during W ...
as
Schering AG
Schering AG was a research-centered German multinational pharmaceutical company headquartered in Wedding, Berlin, which operated as an independent company from 1851 to 2006. In 2006, it was bought by Bayer AG and merged to form the Bayer subs ...
in
Germany
Germany,, officially the Federal Republic of Germany, is a country in Central Europe. It is the second most populous country in Europe after Russia, and the most populous member state of the European Union. Germany is situated betwe ...
.
Plough, Incorporated was founded by the
Memphis, Tennessee
Memphis is a city in the U.S. state of Tennessee. It is the seat of Shelby County in the southwest part of the state; it is situated along the Mississippi River. With a population of 633,104 at the 2020 U.S. census, Memphis is the second-mos ...
area entrepreneur Abe Plough (1892–1984) in 1908. He borrowed $125 from his father to start the business at age sixteen. As a one-man business, he mixed "Plough's Antiseptic Healing Oil," a "sure cure for any ill of man or beast," and sold it off a horse-drawn buggy.
Plough's acquisitions included St Joseph's Aspirin for children,
Maybelline
Maybelline New York (formerly The Maybelline Company and Mabelline and Co.), trading as Maybelline ( ), is an American multinational cosmetics, skin care, fragrance, and personal care company, based in New York City. It was founded in Chicago ...
cosmetics, and
Coppertone
Coppertone is the brand name for an American sunscreen. Coppertone is headquartered in Whippany, New Jersey. Coppertone uses a variety of branding, including the Coppertone girl logo and a distinctive fragrance.
Product line
The original prod ...
skin care products. Plough also had a broadcasting division, operating radio stations in
Atlanta, Georgia
Atlanta ( ) is the capital and most populous city of the U.S. state of Georgia. It is the seat of Fulton County, the most populous county in Georgia, but its territory falls in both Fulton and DeKalb counties. With a population of 498,715 ...
(
WPLO-AM &
FM);
Baltimore, Maryland
Baltimore ( , locally: or ) is the List of municipalities in Maryland, most populous city in the U.S. state of Maryland, fourth most populous city in the Mid-Atlantic (United States), Mid-Atlantic, and List of United States cities by popula ...
(
WCAO-AM &
FM);
Boston, Massachusetts (
WCOP-AM &
FM);
Chicago, Illinois
(''City in a Garden''); I Will
, image_map =
, map_caption = Interactive Map of Chicago
, coordinates =
, coordinates_footnotes =
, subdivision_type = Country
, subdivision_name ...
(
WJJD-AM
WYLL (1160 AM) is a commercial radio station in Chicago, Illinois. It is owned by Salem Media Group and airs a Christian talk and teaching radio format. The studios and offices are located in Elk Grove Village. Its daytime transmitter and tw ...
&
FM); and
Memphis, Tennessee
Memphis is a city in the U.S. state of Tennessee. It is the seat of Shelby County in the southwest part of the state; it is situated along the Mississippi River. With a population of 633,104 at the 2020 U.S. census, Memphis is the second-mos ...
(
WMPS-AM &
FM).
Following the entry of the
United States
The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territorie ...
into
World War II
World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the vast majority of the world's countries—including all of the great powers—forming two opposin ...
in 1941, U.S. President
Franklin Delano Roosevelt
Franklin Delano Roosevelt (; ; January 30, 1882April 12, 1945), often referred to by his initials FDR, was an American politician and attorney who served as the 32nd president of the United States from 1933 until his death in 1945. As the ...
ordered
Schering AG
Schering AG was a research-centered German multinational pharmaceutical company headquartered in Wedding, Berlin, which operated as an independent company from 1851 to 2006. In 2006, it was bought by Bayer AG and merged to form the Bayer subs ...
's U.S. assets be seized. These became the Schering Corporation. The company was placed under a government administratorship until 1952, when it was released, and its assets sold to the private sector.
In 1957, Schering acquired White Laboratories.
In 1971, the Schering Corporation merged with Plough, Inc. At the time of the merger, Abe Plough became Chairman of the combined company.
In 2000, Schering-Plough bought a new campus in
Summit, New Jersey
Summit is a city in Union County, in the U.S. state of New Jersey. The city is located on a ridge in northern- central New Jersey, within the Raritan Valley and Rahway Valley regions in the New York metropolitan area. At the 2010 United Sta ...
from
Novartis
Novartis AG is a Swiss-American multinational pharmaceutical corporation based in Basel, Switzerland and
Cambridge, Massachusetts, United States (global research).name="novartis.com">https://www.novartis.com/research-development/research-loc ...
.
On March 12, 2007, Schering-Plough Corp. purchased
Organon BioSciences, the drug unit of Netherlands-based
Akzo Nobel
Akzo Nobel N.V., stylized as AkzoNobel, is a Dutch multinational company which creates paints and performance coatings for both industry and consumers worldwide. Headquartered in Amsterdam, the company has activities in more than 80 countrie ...
, for $14.4 billion, giving the US pharmaceutical company an array of women's health products and numerous late-stage pipelines of experimental medicines.
''
Organon
The ''Organon'' ( grc, Ὄργανον, meaning "instrument, tool, organ") is the standard collection of Aristotle's six works on logical analysis and dialectic. The name ''Organon'' was given by Aristotle's followers, the Peripatetics.
The si ...
'' itself was founded in 1923 by Dr. Saal van Zwanenberg, the president of Zwanenberg's Slachterijen en Fabrieken.
On November 4, 2009 Schering-Plough merged with
Merck & Co. and through a
reverse merger
A reverse takeover (RTO), reverse merger, or reverse IPO is the acquisition of a public company by a private company so that the private company can bypass the lengthy and complex process of going public. Sometimes, conversely, the public compa ...
, Merck became a subsidiary of Schering-Plough, which renamed itself Merck.
Animal health
Coopers Animal Health
One of Schering-Plough's plants, in
Upper Hutt, New Zealand
Upper Hutt ( mi, Te Awa Kairangi ki Uta) is a city in the Wellington Region of New Zealand and one of the four cities that constitute the Wellington metropolitan area.
Geography
The Upper Hutt city centre lies approximately 26 km north-e ...
was the largest single site for the production of veterinary
vaccines
A vaccine is a biological preparation that provides active acquired immunity
The adaptive immune system, also known as the acquired immune system, is a subsystem of the immune system that is composed of specialized, systemic cells and pro ...
in the world. This was primarily because
New Zealand
New Zealand ( mi, Aotearoa ) is an island country in the southwestern Pacific Ocean. It consists of two main landmasses—the North Island () and the South Island ()—and over 700 smaller islands. It is the sixth-largest island count ...
's isolation has formed a natural
quarantine
A quarantine is a restriction on the movement of people, animals and goods which is intended to prevent the spread of disease or pests. It is often used in connection to disease and illness, preventing the movement of those who may have been ...
, leaving the country free of
rabies
Rabies is a viral disease that causes encephalitis in humans and other mammals. Early symptoms can include fever and tingling at the site of exposure. These symptoms are followed by one or more of the following symptoms: nausea, vomiting, vi ...
,
foot and mouth
Foot-and-mouth disease (FMD) or hoof-and-mouth disease (HMD) is an infectious and sometimes fatal viral disease that affects cloven-hoofed animals, including domestic and wild bovids. The virus causes a high fever lasting two to six days, follow ...
,
scrapie
Scrapie () is a fatal, degenerative disease affecting the nervous systems of sheep and goats. It is one of several transmissible spongiform encephalopathies (TSEs), and as such it is thought to be caused by a prion. Scrapie has been known since ...
,
bovine spongiform encephalopathy
Bovine spongiform encephalopathy (BSE), commonly known as mad cow disease, is an incurable and invariably fatal neurodegenerative disease of cattle. Symptoms include abnormal behavior, trouble walking, and weight loss. Later in the course of t ...
, and many other livestock diseases. It formerly had
echinococcosis
Echinococcosis is a parasitic disease of tapeworms of the ''Echinococcus'' type. The two main types of the disease are ''cystic echinococcosis'' and '' alveolar echinococcosis''. Less common forms include ''polycystic echinococcosis'' and ''uni ...
, but this has been eradicated. The site was known locally as Coopers Animal Health, a trademark which originated in the 1850s with a British company,
Cooper & Nephews; the Coopers brand name was still in use by Schering-Plough in Australia, but not elsewhere.
Intervet
As a result of the acquisition of Organon BioSciences, Schering-Plough bolstered its animal health business with the
Akzo Nobel
Akzo Nobel N.V., stylized as AkzoNobel, is a Dutch multinational company which creates paints and performance coatings for both industry and consumers worldwide. Headquartered in Amsterdam, the company has activities in more than 80 countrie ...
subsidiary Intervet, obtained control of the active pharmaceutical ingredient manufacturer,
Diosynth and gained access to human vaccine production through the subsidiary Nobilon. The three companies comprising Organon BioSciences were Organon, Diosynth, and Intervet.
HomeAgain continues to use the Intervet name owned by Merck.
Merck Animal Health, MSD Animal Health
After the merger of Schering-Plough with Merck the animal health division was still known as Intervet/Schering-Plough Animal Health. A merger of Merial and Intervet/Schering-Plough was planned in 2010 but was abandoned in March 2011. On June 29, 2011, the company announced that the animal health division would now be known as Merck Animal Health in the United States and Canada; it is now called MSD Animal Health elsewhere in the world.
Chief executives
Medical products
Prescription products
*Bridion (
sugammadex
Sugammadex, sold under the brand name Bridion, is a medication for the reversal of neuromuscular blockade induced by rocuronium and vecuronium in general anaesthesia. It is the first selective relaxant binding agent (SRBA). It is marketed by Mer ...
)
*Cerazette
*
Desloratadine:
antihistamine
Antihistamines are drugs which treat allergic rhinitis, common cold, influenza, and other allergies. Typically, people take antihistamines as an inexpensive, generic (not patented) drug that can be bought without a prescription and provides re ...
branded ''Clarinex''
*Esmeron/Zemuron (
rocuronium
Rocuronium bromide (brand names Zemuron, Esmeron) is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate tracheal intubation by providing skeletal muscle relaxation, most commonly ...
)
*Famvir (
Famciclovir
Famciclovir is a guanosine analogue antiviral drug used for the treatment of various herpesvirus infections, most commonly for herpes zoster (shingles). It is a prodrug form of penciclovir with improved oral bioavailability. Famciclovir is mark ...
): for
Shingles
Shingles, also known as zoster or herpes zoster, is a viral disease characterized by a painful skin rash with blisters in a localized area. Typically the rash occurs in a single, wide mark either on the left or right side of the body or face. ...
(herpes zoster) treatment, developed by
Novartis
Novartis AG is a Swiss-American multinational pharmaceutical corporation based in Basel, Switzerland and
Cambridge, Massachusetts, United States (global research).name="novartis.com">https://www.novartis.com/research-development/research-loc ...
*Intron A & PEG-Intron
Interferon alfa-2b
Interferon alfa-2b is an antiviral or antineoplastic drug. It is a recombinant form of the protein Interferon alpha-2 that was originally sequenced and produced recombinantly in '' E. coli'' in the laboratory of Charles Weissmann at the Univers ...
: for treatment of
hepatitis C
Hepatitis C is an infectious disease caused by the hepatitis C virus (HCV) that primarily affects the liver; it is a type of viral hepatitis. During the initial infection people often have mild or no symptoms. Occasionally a fever, dark urine, a ...
*Levitra (
vardenafil
Vardenafil is a PDE5 inhibitor used for treating erectile dysfunction that is sold under the brand name Levitra among others.
Medical use
Vardenafil's indications and contraindications are the same as with other PDE5 inhibitors; it is closel ...
): Erectile-dysfunction drug; co-marketed with
Bayer
Bayer AG (, commonly pronounced ; ) is a German multinational corporation, multinational pharmaceutical and biotechnology company and one of the largest pharmaceutical companies in the world. Headquartered in Leverkusen, Bayer's areas of busi ...
, and
GlaxoSmithKline
GSK plc, formerly GlaxoSmithKline plc, is a British multinational pharmaceutical and biotechnology company with global headquarters in London, England. Established in 2000 by a merger of Glaxo Wellcome and SmithKline Beecham. GSK is the ten ...
*Livial (
tibolone
Tibolone, sold under the brand name Livial among others, is a medication which is used in menopausal hormone therapy and in the treatment of postmenopausal osteoporosis and endometriosis. The medication is available alone and is not formulated ...
)
*Marvelon/Desogen
*Nasonex and Asmanex (
Mometasone furoate
Mometasone, also known as mometasone y 3 s, is a steroid medication used to treat certain skin conditions, hay fever, and asthma. Specifically it is used to prevent rather than treat asthma attacks. It can be applied to the skin, inhaled, or use ...
)
*Noxafil (
posaconazole
Posaconazole, sold under the brand name Noxafil among others, is a triazole antifungal medication.
It was approved for medical use in the United States in September 2006, and is available as a generic medication.
Medical uses
Posaconazole is u ...
)
*NuvaRing
*Puregon/Follistim
*
Quazepam
Quazepam, sold under brand name Doral among others, is a relatively long-acting benzodiazepine derivative drug developed by the Schering Corporation in the 1970s. Quazepam is used for the treatment of insomnia including sleep induction and sleep ...
(Doral)
*Remeron/Remeron SolTab (
mirtazapine
Mirtazapine, sold under the brand name Remeron amongst others, is an atypical antidepressant, and as such is used primarily to treat depression. Its effects may take up to four weeks, but can also manifest as early as one to two weeks. It is o ...
)
*Remicade (
infliximab
Infliximab, a chimeric monoclonal antibody, sold under the brand name Remicade among others, is a medication used to treat a number of autoimmune diseases. This includes Crohn's disease, ulcerative colitis, rheumatoid arthritis, ankylosing spon ...
)
*Suboxone (
Buprenorphine
Buprenorphine is an opioid used to treat opioid use disorder, acute pain, and chronic pain. It can be used under the tongue (sublingual), in the cheek (buccal), by injection (intravenous and subcutaneous), as a skin patch (transdermal ...
/Naloxone)
*Temodar (
temozolomide
Temozolomide (TMZ), sold under the brand name Temodar among others, is a medication used to treat brain tumors such as glioblastoma and anaplastic astrocytoma. Text was copied from this source which is © European Medicines Agency. Reproduction ...
)
*Vytorin (
ezetimibe/simvastatin
Ezetimibe/simvastatin is a drug combination used for the treatment of dyslipidemia. It is a combination of ezetimibe (known as Zetia in the United States) and the statin drug simvastatin (known as Zocor in the US).
Ezetimibe reduces blood choles ...
): Cholesterol-lowering combination drug
*Zetia (
ezetimibe
Ezetimibe is a medication used to treat high blood cholesterol and certain other lipid abnormalities. Generally it is used together with dietary changes and a statin. Alone, it is less preferred than a statin. It is taken by mouth. It is also ...
): Cholesterol-lowering drug
Over-the-counter products (Most products sold to
Bayer
Bayer AG (, commonly pronounced ; ) is a German multinational corporation, multinational pharmaceutical and biotechnology company and one of the largest pharmaceutical companies in the world. Headquartered in Leverkusen, Bayer's areas of busi ...
, except
Coppertone
Coppertone is the brand name for an American sunscreen. Coppertone is headquartered in Whippany, New Jersey. Coppertone uses a variety of branding, including the Coppertone girl logo and a distinctive fragrance.
Product line
The original prod ...
)
*
Afrin: A
nasal spray
Nasal sprays are used to deliver medications locally in the nasal cavities or systemically. They are used locally for conditions such as nasal congestion and allergic rhinitis. In some situations, the nasal delivery route is preferred for syste ...
decongestant
*Claritin (
loratadine
Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. This includes allergic rhinitis (hay fever) and hives. It is also available in combination with pseudoephedrine, a decongestant, known as lora ...
): An
antihistamine
Antihistamines are drugs which treat allergic rhinitis, common cold, influenza, and other allergies. Typically, people take antihistamines as an inexpensive, generic (not patented) drug that can be bought without a prescription and provides re ...
which has less risk of causing
drowsiness
Somnolence (alternatively sleepiness or drowsiness) is a state of strong desire for sleep, or sleeping for unusually long periods (compare hypersomnia). It has distinct meanings and causes. It can refer to the usual state preceding falling asleep ...
*Correctol: A
stimulant laxative
Laxatives, purgatives, or aperients are substances that loosen human feces, stools and increase defecation, bowel movements. They are used to treat and prevent constipation.
Laxatives vary as to how they work and the side effects they may have. ...
incorporating
dioctyl sodium sulfosuccinate
Docusate is the common chemical and pharmaceutical name of the anion bis(2-ethylhexyl) sulfosuccinate, also commonly called dioctyl sulfosuccinate (DOSS).
It is on the WHO Model List of Essential Medicines, World Health Organization's List of E ...
and yellow
phenolphthalein
Phenolphthalein ( ) is a chemical compound with the chemical formula, formula carbon, C20hydrogen, H14oxygen, O4 and is often written as "HIn", "HPh", "phph" or simply "Ph" in shorthand notation. Phenolphthalein is often used as an indicator in ...
*
Coricidin
Coricidin, Coricidin 'D' (decongestant), or Coricidin HBP (for high blood pressure), is the name of an over-the-counter cough and cold drug containing dextromethorphan (a cough suppressant) and chlorpheniramine maleate (an antihistamine). Introdu ...
: A
palliative remedy for the
common cold
The common cold or the cold is a viral infectious disease of the upper respiratory tract that primarily affects the respiratory mucosa of the nose, throat, sinuses, and larynx. Signs and symptoms may appear fewer than two days after exposu ...
, targeted towards individuals with
high blood pressure
Hypertension (HTN or HT), also known as high blood pressure (HBP), is a long-term medical condition in which the blood pressure in the arteries is persistently elevated. High blood pressure usually does not cause symptoms. Long-term high bl ...
*
Coppertone
Coppertone is the brand name for an American sunscreen. Coppertone is headquartered in Whippany, New Jersey. Coppertone uses a variety of branding, including the Coppertone girl logo and a distinctive fragrance.
Product line
The original prod ...
: sunscreens
*
Bain de Soleil: sunscreen
*Drixoral
*Solarcaine: Sunburn relief
*
Zinka: Colored sunscreen
Veterinary products
*
Home Again Pet Recovery System: HomeAgain is an advanced pet identification and retrieval system.
*
Zubrin: A non-steroidal anti-inflammatory drug (
NSAID
Non-steroidal anti-inflammatory drugs (NSAID) are members of a therapeutic drug class which reduces pain, decreases inflammation, decreases fever, and prevents blood clots. Side effects depend on the specific drug, its dose and duration of ...
) for the treatment of
osteoarthritis
Osteoarthritis (OA) is a type of degenerative joint disease that results from breakdown of joint cartilage and underlying bone which affects 1 in 7 adults in the United States. It is believed to be the fourth leading cause of disability in the w ...
in dogs.
*
Mometamax: Is indicated for the treatment of
canine acute externa and
chronic otitis externa associated with
yeast
Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom. The first yeast originated hundreds of millions of years ago, and at least 1,500 species are currently recognized. They are estimated to constitut ...
(
Malassezia pachydermatis, formerly
Pityrosporum canis) and/or
bacteria
Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among ...
susceptible to
gentamicin
Gentamicin is an antibiotic used to treat several types of bacterial infections. This may include bone infections, endocarditis, pelvic inflammatory disease, meningitis, pneumonia, urinary tract infections, and sepsis among others. It is not e ...
. It contains the strongest steroid (
Mometasone furoate
Mometasone, also known as mometasone y 3 s, is a steroid medication used to treat certain skin conditions, hay fever, and asthma. Specifically it is used to prevent rather than treat asthma attacks. It can be applied to the skin, inhaled, or use ...
) in Veterinary Medicine.
*
Eclipse Vaccines
An eclipse is an astronomical event that occurs when an astronomical object or spacecraft is temporarily obscured, by passing into the shadow of another body or by having another body pass between it and the viewer. This alignment of three cel ...
: Attenuated modified live feline vaccines available in a multitude of
antigen
In immunology, an antigen (Ag) is a molecule or molecular structure or any foreign particulate matter or a pollen grain that can bind to a specific antibody or T-cell receptor. The presence of antigens in the body may trigger an immune response. ...
combinations.
*
Galaxy Vaccines: Canine vaccines available in a multitude of
antigen
In immunology, an antigen (Ag) is a molecule or molecular structure or any foreign particulate matter or a pollen grain that can bind to a specific antibody or T-cell receptor. The presence of antigens in the body may trigger an immune response. ...
combinations.
*
Optimmune: Ophthalmic ointment (ciclosporin) for the treatment of Pannis and
Keratoconjunctivitis sicca
Dry eye syndrome (DES), also known as keratoconjunctivitis sicca (KCS), is the condition of having dry eyes. Other associated symptoms include irritation, redness, discharge, and easily fatigued eyes. Blurred vision may also occur. Symptoms range ...
in dogs.
*
Orbax: Trade name for
orbifloxacin, a
fluoroquinolone
A quinolone antibiotic is a member of a large group of broad-spectrum bacteriocidals that share a bicyclic core structure related to the substance 4-quinolone. They are used in human and veterinary medicine to treat bacterial infections, as wel ...
.
*
Otomax: Is indicated for the treatment of
canine acute otitis externa and
chronic otitis externa associated with
yeast
Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom. The first yeast originated hundreds of millions of years ago, and at least 1,500 species are currently recognized. They are estimated to constitut ...
(
Malassezia pachydermatis, formerly
Pityrosporum canis) and/or
bacteria
Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among ...
susceptible to
gentamicin
Gentamicin is an antibiotic used to treat several types of bacterial infections. This may include bone infections, endocarditis, pelvic inflammatory disease, meningitis, pneumonia, urinary tract infections, and sepsis among others. It is not e ...
. It contains betamethasone valerate as an anti-inflammatory.
*
Banamine: A non-steroidal anti-inflammatory drug (
NSAID
Non-steroidal anti-inflammatory drugs (NSAID) are members of a therapeutic drug class which reduces pain, decreases inflammation, decreases fever, and prevents blood clots. Side effects depend on the specific drug, its dose and duration of ...
) used in horses, cattle and swine in different parts of the world.
*
Estrumate: A synthetic
prostaglandin
The prostaglandins (PG) are a group of physiologically active lipid compounds called eicosanoids having diverse hormone-like effects in animals. Prostaglandins have been found in almost every tissue in humans and other animals. They are derive ...
used in reproduction of cattle.
*
Trivetrin:
Trimethoprin sulfate for the treatment of cattle and swine.
*Nuflor-Florfenicol-for treatment of
bovine respiratory disease
Bovine respiratory disease (BRD) is the most common and costly disease affecting beef cattle in the world. It is a complex, bacterial or viral infection that causes pneumonia in calves which can be fatal. The infection is usually a sum of three c ...
, foot rot and control of respiratory disease in cattle at high risk of developing bovine respiratory disease.
Exercise drug
Schering-Plough also received much publicity for a drug
AICAR which mimics the effects of exercise, having especially potent effects when used alongside another drug
GW1516
GW501516 (also known as GW-501,516, GW1516, GSK-516, Cardarine, and on the black market as Endurobol) is a PPARδ receptor agonist that was invented in a collaboration between Ligand Pharmaceuticals and GlaxoSmithKline in the 1990s. It entered ...
developed by
GlaxoSmithKline
GSK plc, formerly GlaxoSmithKline plc, is a British multinational pharmaceutical and biotechnology company with global headquarters in London, England. Established in 2000 by a merger of Glaxo Wellcome and SmithKline Beecham. GSK is the ten ...
.
Collaborative research
In addition to internal research and development activities Schering-Plough was also involved in publicly funded collaborative research projects, with other industrial and academic partners. One example in
non-clinical safety assessment was the
InnoMed PredTox.
Controversy
In 2004, Schering-Plough was accused of marketing gimmicks and payoffs to doctors for prescribing the company's pharmaceutical products.
Schering-Plough entered a
consent decree with the FDA on March 6, 2002 due to manufacturing issues with its albuterol inhaler. It was ordered to pay $500 million US dollars to the US Treasury.
References
External links
Yahoo! - Schering-Plough Corporation Company Profile
{{Authority control
Merck & Co.
1971 establishments in New Jersey
2009 mergers and acquisitions
2009 disestablishments in New Jersey
American companies established in 1971
Companies based in Union County, New Jersey
Companies formerly listed on the New York Stock Exchange
Defunct companies based in New Jersey
Defunct pharmaceutical companies of the United States
Pharmaceutical companies established in 1971
Pharmaceutical companies disestablished in 2009
Pharmaceutical companies based in New Jersey