Resorcylic acid lactones are a group of
estrogen
Estrogen or oestrogen is a category of sex hormone responsible for the development and regulation of the female reproductive system and secondary sex characteristics. There are three major endogenous estrogens that have estrogenic hormonal acti ...
ic
compound
Compound may refer to:
Architecture and built environments
* Compound (enclosure), a cluster of buildings having a shared purpose, usually inside a fence or wall
** Compound (fortification), a version of the above fortified with defensive struct ...
s. They are
lactone
Lactones are cyclic carboxylic esters, containing a 1-oxacycloalkan-2-one structure (), or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
Lactones are formed by intramolecular esterification of the co ...
s of
resorcylic acid Resorcylic acid is a type of dihydroxybenzoic acid. It may refer to:
*3,5-Dihydroxybenzoic acid
3,5-Dihydroxybenzoic acid (α-resorcylic acid) is a dihydroxybenzoic acid. It is a colorless solid.
Preparation and occurrence
It is prepared by disu ...
. Examples include the
mycoestrogen Mycoestrogens are xenoestrogens produced by fungi. They are sometimes referred to as mycotoxins. Among important mycoestrogens are zearalenone, zearalenol and zearalanol. Although all of these can be produced by various ''Fusarium'' species, zea ...
s (and
synthetic analogues)
zearalenone
Zearalenone (ZEN), also known as RAL and F-2 mycotoxin, is a potent estrogenic metabolite produced by some ''Fusarium'' and ''Gibberella'' species. Specifically, the ''Gibberella zeae ,'' the fungal species where zearalenone was initially detected ...
,
zearalanone
Zearalanone (ZAN) is a semi-synthetic mycoestrogen that is a derivative of zearalenone
Zearalenone (ZEN), also known as RAL and F-2 mycotoxin, is a potent estrogenic metabolite produced by some ''Fusarium'' and ''Gibberella'' species. Specificall ...
,
zeranol
Zeranol (, , ) (brand names Frideron, Ralabol, Ralgro, Ralone, Zerano; developmental code names MK-188, P-1496), or zearanol, also known as α-zearalanol or simply zearalanol, is a synthetic nonsteroidal estrogen of the resorcylic acid lactone
R ...
(α-zearalanol),
taleranol
Taleranol (International Nonproprietary Name, INN, United States Adopted Name, USAN) (developmental code name P-1560), or teranol, also known as β-zearalanol, is a synthetic compound, synthetic, nonsteroidal estrogen of the resorcylic acid lacto ...
(β-zearalanol),
α-zearalenol
α-Zearalenol is a nonsteroidal estrogen of the resorcylic acid lactone group related to mycoestrogens found in ''Fusarium, Fusarium spp''. It is the α epimer of β-zearalenol and along with β-zearalenol is a major metabolite of zearalenone for ...
, and
β-zearalenol
β-Zearalenol is a nonsteroidal estrogen of the resorcylic acid lactone group related to mycoestrogens found in '' Fusarium spp''. It is the β epimer of α-zearalenol and along with α-zearalenol is a major metabolite of zearalenone formed main ...
.
References
Dihydroxybenzoic acids
Lactones
Mycoestrogens
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