A reflex arc is a

neural pathway In neuroanatomy, a neural pathway is the connection formed by axons that project from neurons to make synapses onto neurons in another location, to enable neurotransmission (the sending of a signal from one region of the nervous system to ...

that controls a

reflex In biology, a reflex, or reflex action, is an involuntary, unplanned sequence or action and nearly instantaneous response to a stimulus. Reflexes are found with varying levels of complexity in organisms with a nervous system. A reflex occurs ...

. In

vertebrate Vertebrates () comprise all animal taxa within the subphylum Vertebrata () ( chordates with backbones), including all mammals, birds, reptiles, amphibians, and fish. Vertebrates represent the overwhelming majority of the phylum Chordata, with ...

s, most

sensory neuron Sensory neurons, also known as afferent neurons, are neurons in the nervous system, that convert a specific type of stimulus, via their receptors, into action potentials or graded potentials. This process is called sensory transduction. The ...

s do not pass directly into the

brain A brain is an organ (biology), organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It is located in the head, usually close to the sensory organs for senses such as Visual perception, vision. I ...

, but

synapse In the nervous system, a synapse is a structure that permits a neuron (or nerve cell) to pass an electrical or chemical signal to another neuron or to the target effector cell. Synapses are essential to the transmission of nervous impulses from ...

in the

spinal cord The spinal cord is a long, thin, tubular structure made up of nervous tissue, which extends from the medulla oblongata in the brainstem to the lumbar region of the vertebral column (backbone). The backbone encloses the central canal of the spi ...

. This allows for faster reflex actions to occur by activating spinal

motor neuron A motor neuron (or motoneuron or efferent neuron) is a neuron whose cell body is located in the motor cortex, brainstem or the spinal cord, and whose axon (fiber) projects to the spinal cord or outside of the spinal cord to directly or indirectl ...

s without the delay of routing signals through the brain. The brain will receive the input while the reflex is being carried out and the analysis of the signal takes place after the reflex action. There are two types: autonomic reflex arc (affecting inner organs) and

somatic Somatic may refer to: * Somatic (biology), referring to the cells of the body in contrast to the germ line cells ** Somatic cell, a non-gametic cell in a multicellular organism * Somatic nervous system, the portion of the vertebrate nervous sys ...

reflex arc (affecting muscles). Autonomic reflexes sometimes involve the spinal cord and some somatic reflexes are mediated more by the brain than the spinal cord. During a somatic reflex, nerve signals travel along the following pathway: # ''Somatic receptors'' in the skin, muscles and tendons # ''Afferent nerve fibers'' carry signals from the somatic receptors to the posterior horn of the spinal cord or to the brainstem # An ''integrating center'', the point at which the neurons that compose the gray matter of the spinal cord or brainstem synapse # ''Efferent nerve fibers'' carry motor nerve signals from the anterior horn to the muscles # ''Effector'' muscle innervated by the efferent nerve fiber carries out the response. A reflex arc, then, is the pathway followed by nerves which (a.) carry sensory information from the receptor to the spinal cord, and then (b.) carry the response generated by the spinal cord to effector organs during a reflex action. The pathway taken by the nerve impulse to accomplish a reflex action is called the reflex arc.

Monosynaptic vs. polysynaptic

When a reflex arc in an animal consists of only one

and one

, it is defined as monosynaptic, referring to the presence of a single

chemical synapse Chemical synapses are biological junctions through which neurons' signals can be sent to each other and to non-neuronal cells such as those in muscles or glands. Chemical synapses allow neurons to form circuits within the central nervous syst ...

. In the case of peripheral muscle reflexes ( patellar reflex,

achilles reflex The ankle jerk reflex, also known as the Achilles reflex, occurs when the Achilles tendon is tapped while the foot is dorsiflexed. It is a type of stretch reflex that tests the function of the gastrocnemius muscle and the nerve that supplies it. ...

), brief stimulation to the

muscle spindle Muscle spindles are stretch receptors within the body of a skeletal muscle that primarily detect changes in the length of the muscle. They convey length information to the central nervous system via afferent nerve fibers. This information can be ...

results in contraction of the agonist or effector muscle. By contrast, in polysynaptic reflex pathways, one or more interneurons connect afferent ( sensory) and efferent (

motor An engine or motor is a machine designed to convert one or more forms of energy into mechanical energy. Available energy sources include potential energy (e.g. energy of the Earth's gravitational field as exploited in hydroelectric power g ...

) signals. All but the most simple reflexes are polysynaptic, allowing processing or inhibition of polysynaptic reflexes within the brain.

The patellar reflex (aka "knee jerk")

Reflex arc of decapod including LG interneuron (1)

When the

patellar tendon The patellar tendon is the distal portion of the common tendon of the quadriceps femoris, which is continued from the patella to the tibial tuberosity. It is also sometimes called the patellar ligament as it forms a bone to bone connection when ...

is tapped just below the knee, the tap initiates an

action potential An action potential occurs when the membrane potential of a specific cell location rapidly rises and falls. This depolarization then causes adjacent locations to similarly depolarize. Action potentials occur in several types of animal cells, ...

in a specialized structure known as a

located within the

quadriceps The quadriceps femoris muscle (, also called the quadriceps extensor, quadriceps or quads) is a large muscle group that includes the four prevailing muscles on the front of the thigh. It is the sole extensor muscle of the knee, forming a large ...

. This action potential travels to the L3 and L4 nerve roots of the spinal cord, via a sensory

axon An axon (from Greek ἄξων ''áxōn'', axis), or nerve fiber (or nerve fibre: see spelling differences), is a long, slender projection of a nerve cell, or neuron, in vertebrates, that typically conducts electrical impulses known as action po ...

which chemically communicates by releasing

glutamate Glutamic acid (symbol Glu or E; the ionic form is known as glutamate) is an α-amino acid that is used by almost all living beings in the biosynthesis of proteins. It is a non-essential nutrient for humans, meaning that the human body can syn ...

onto a

motor nerve A motor nerve is a nerve that transmits motor signals from the central nervous system (CNS) to the muscles of the body. This is different from the motor neuron, which includes a cell body and branching of dendrites, while the nerve is made up of ...

. The result of this motor nerve activity is contraction of the quadriceps muscle, leading to extension of the lower leg at the knee (i.e. the lower leg kicks forward). Ultimately, an improper patellar reflex may indicate an injury of the

central nervous system The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain and spinal cord. The CNS is so named because the brain integrates the received information and coordinates and influences the activity of all par ...

. The sensory input from the quadriceps also activates local

interneuron Interneurons (also called internuncial neurons, relay neurons, association neurons, connector neurons, intermediate neurons or local circuit neurons) are neurons that connect two brain regions, i.e. not direct motor neurons or sensory neurons. I ...

s that release the inhibitory

neurotransmitter A neurotransmitter is a signaling molecule secreted by a neuron to affect another cell across a synapse. The cell receiving the signal, any main body part or target cell, may be another neuron, but could also be a gland or muscle cell. Neuro ...

glycine Glycine (symbol Gly or G; ) is an amino acid that has a single hydrogen atom as its side chain. It is the simplest stable amino acid (carbamic acid is unstable), with the chemical formula NH2‐ CH2‐ COOH. Glycine is one of the proteinogeni ...

onto motor neurons of

antagonist An antagonist is a character in a story who is presented as the chief foe of the protagonist. Etymology The English word antagonist comes from the Greek ἀνταγωνιστής – ''antagonistēs'', "opponent, competitor, villain, enemy, riv ...

muscles, blocking their stimulation (in this case the

hamstring muscles In human anatomy, a hamstring () is any one of the three posterior thigh muscles in between the hip and the knee (from medial to lateral: semimembranosus, semitendinosus and biceps femoris). The hamstrings are susceptible to injury. In quadrupeds, ...

). The relaxation of the opposing muscle facilitates (by not opposing) the extension of the lower leg. In invertebrates reflex interneurons do not necessarily reside in the spinal cord, for example as in the

lateral giant neuron The lateral giant interneuron (LG) is an interneuron in the abdominal nerve cord of crayfish, lobsters, shrimp of the order Decapoda and their relatives in the crustacean class Malacostraca. It is part of the system that controls a specia ...

crayfish Crayfish are freshwater crustaceans belonging to the clade Astacidea, which also contains lobsters. In some locations, they are also known as crawfish, craydids, crawdaddies, crawdads, freshwater lobsters, mountain lobsters, rock lobsters, mu ...

References

External links

* {{Cite thesis , author = Ole Kæseler Andersen , url = http://person.hst.aau.dk/oka/oka_phd_thesis.pdf , title = Physiological and Pharmacological modulation of the human nociceptive withdrawal reflex , type = PhD Thesis , publisher = Center for Sansory-Motor Interaction, Aalborg University , date = 1996
Overview at sfsu.edu

Tutorial at wisc-online.com
Reflexes

Monosynaptic vs. polysynaptic

The patellar reflex (aka "knee jerk")

See also

References

External links