Retinoic acid early transcript 1E (RAET1E) is a cell surface glycoprotein encoded by ''RAET1E'' gene located on the chromosome 6.
RAET1E is related to
MHC class I
MHC class I molecules are one of two primary classes of major histocompatibility complex (MHC) molecules (the other being MHC class II) and are found on the cell surface of all nucleated cells in the bodies of vertebrates. They also occur on plat ...
molecules, but its gene maps outside the MHC locus.
RAET1E is composed of external α1α2 domain, transmembrane segment and C-terminal cytoplasmic tail.
RAET1E functions as a
stress-induced ligand for
NKG2D receptor.
References
Further reading
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