The quantitative insulin sensitivity check index (''QUICKI'') is derived using the inverse of the sum of the logarithms of the fasting
insulin and fasting
glucose
Glucose is a simple sugar with the molecular formula . Glucose is overall the most abundant monosaccharide, a subcategory of carbohydrates. Glucose is mainly made by plants and most algae during photosynthesis from water and carbon dioxide, u ...
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This index correlates well with
glucose clamp studies (r = 0.78), and is useful for measuring insulin sensitivity (IS), which is the inverse of insulin resistance (IR). It has the advantage of that it can be obtained from a fasting blood sample, and is the preferred method for certain types of clinical research.
Values typically associated with the QUICKI calculation for insulin resistance in humans fall broadly within a range between 0.45 for unusually healthy individuals and 0.30 in diabetics. So lower numbers reflect greater insulin resistance.
See also
*
SPINA-GBeta
*
SPINA-GR
*
Homeostatic model assessment The homeostatic model assessment (HOMA) is a method used to quantify insulin resistance and beta-cell function. It was first described under the name HOMA by Matthews ''et al.'' in 1985.
Derivation
The HOMA authors used data from physiological stu ...
Sources
* Katz A, Nambi SS, Mather K, Baron AD, Follmann DA, Sullivan G, Quon MJ. Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans. J Clin Endocrinol Metab. 2000 Jul;85(7):2402-10.
Source as above - Katz et al. Also data for unusually healthy individuals derived from those practicing caloric restriction. See CR Society for details.
Diabetes
Static endocrine function tests
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