ProteoWizard is a set of open-source, cross-platform tools and libraries for proteomics data analyses.
It provides a framework for unified mass spectrometry data file access and performs standard chemistry and LCMS dataset computations. Specifically, it is able to read many of the vendor-specific, proprietary formats and converting the data into an open data format.
On the application level, the software provides executables for data conversion (msConvert, msConvertGUI and idConvert), data visualization (msPicture and seeMS), data access (msAccess, msCat, idCat and msPicture), data analysis (peekaboo and msPrefix14) and basic proteomics utilities (chainsaw). In addition, the project also hosts the Skyline software which helps to create, acquire and analyze targeted proteomics experiments such as
SRM experiments.
The main contributors to the project are the Tabb, MacCoss and Mallick research labs as well as Insilicos.
ProteoWizard: Team
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See also
* OpenMS
* Trans-Proteomic Pipeline
The Trans-Proteomic Pipeline (TPP) is an open-source data analysis software for proteomics developed at the Institute for Systems Biology (ISB) by the Ruedi Aebersold group under the Seattle Proteome Center. The TPP includes PeptideProphet, Pr ...
* Mass spectrometry software
References
[{{Cite journal , last1 = Chambers , first1 = MC. , last2 = Maclean , first2 = B. , last3 = Burke , first3 = R. , last4 = Amodei , first4 = D. , last5 = Ruderman , first5 = DL. , last6 = Neumann , first6 = S. , last7 = Gatto , first7 = L. , last8 = Fischer , first8 = B. , last9 = Pratt , first9 = B. , last10 = Egertson , first10 = Jarrett , last11 = Hoff , first11 = Katherine , last12 = Kessner , first12 = Darren , last13 = Tasman , first13 = Natalie , last14 = Shulman , first14 = Nicholas , last15 = Frewen , first15 = Barbara , last16 = Baker , first16 = Tahmina A , last17 = Brusniak , first17 = Mi-Youn , last18 = Paulse , first18 = Christopher , last19 = Creasy , first19 = David , last20 = Flashner , first20 = Lisa , last21 = Kani , first21 = Kian , last22 = Moulding , first22 = Chris , last23 = Seymour , first23 = Sean L , last24 = Nuwaysir , first24 = Lydia M , last25 = Lefebvre , first25 = Brent , last26 = Kuhlmann , first26 = Frank , last27 = Roark , first27 = Joe , last28 = Rainer , first28 = Paape , last29 = Detlev , first29 = Suckau , last30 = Hemenway , first30 = Tina , title = A cross-platform toolkit for mass spectrometry and proteomics , journal = Nat Biotechnol , volume = 30 , issue = 10 , pages = 918–20 , date=Oct 2012 , doi = 10.1038/nbt.2377 , pmid = 23051804 , display-authors = 8 , pmc = 3471674 ]
External links
Project Homepage
Skyline Homepage
Free science software
Bioinformatics software
Mass spectrometry software
Proteomics
Software using the Apache license