Pipecuronium (Arduan) is a bisquaternary
aminosteroid muscle relaxant which blocks
nicotinic acetylcholine receptors at the
neuromuscular junction
A neuromuscular junction (or myoneural junction) is a chemical synapse between a motor neuron and a muscle fiber.
It allows the motor neuron to transmit a signal to the muscle fiber, causing muscle contraction.
Muscles require innervation to ...
. It is also an antagonist of
M2 and
M3 muscarinic receptors
The muscarinic acetylcholine receptor, also known as cholinergic/acetylcholine receptor M3, or the muscarinic 3, is a muscarinic acetylcholine receptor encoded by the human gene CHRM3.
The M3 muscarinic receptors are located at many places in t ...
and is the most
potent neuromuscular blocking agent of the aminosteroid class.
It is sold under the
trade names Arduan and Pycuron.
See also
*
Pancuronium bromide
References
Muscle relaxants
Quaternary ammonium compounds
Piperazines
Acetate esters
Bromides
Nicotinic antagonists
Androstanes
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