This family contains
acyltransferase
Acyltransferase is a type of transferase enzyme that acts upon acyl groups.
Examples include:
* Glyceronephosphate O-acyltransferase
* Lecithin-cholesterol acyltransferase
*Long-chain-alcohol O-fatty-acyltransferase
In enzymology, a long-chain- ...
s involved in
phospholipid
Phospholipids, are a class of lipids whose molecule has a hydrophilic "head" containing a phosphate group and two hydrophobic "tails" derived from fatty acids, joined by an alcohol residue (usually a glycerol molecule). Marine phospholipids typ ...
biosynthesis and proteins of unknown function.
This family also includes
tafazzin,
the
Barth syndrome
Barth syndrome (BTHS) is a rare but serious X-linked genetic disorder, caused by changes in phospholipid structure and metabolism. It may affect multiple body systems (though mainly characterized by pronounced pediatric-onset cardiomyopathy), and ...
gene.
Subfamilies
*
1-acyl-sn-glycerol-3-phosphate acyltransferase
Human proteins containing this domain
AGPAT1;
AGPAT2;
AGPAT3;
AGPAT4;
AGPAT5;
AGPAT6;
AGPAT7;
AYTL1;
AYTL2;
GNPAT
Glyceronephosphate O-acyltransferase is an enzyme associated with Rhizomelic chondrodysplasia punctata type 2.
GNPAT is located on chromosome 1 on the plus strand. The gene C1orf131 is located directly upstream of it, and the closest downstream ge ...
;
GPAM
Glycerol-3-phosphate acyltransferase 1, mitochondrial is an enzyme that in humans is encoded by the ''GPAM'' gene.
Glycerol-3-phosphate acyltransferase (GPAT; EC 2.3.1.15), which catalyzes the initial and committing step in glycerolipid biosynth ...
;
GPAT3;
LYCAT;
TAZ Taz or TAZ may refer to:
Geography
*Taz (river), a river in western Siberia, Russia
*Taz Estuary, the estuary of the river Taz in Russia
People
* Taz people, an ethnic group in Russia
** Taz language, a form of Northeastern Mandarin spoken by ...
;
TMEM68;
References
Protein domains
Protein families
{{membrane-protein-stub