Paronychia Kapela
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Paronychia is an inflammation of the skin around the nail, which can occur suddenly, when it is usually due to the bacterium ''
Staphylococcus aureus ''Staphylococcus aureus'' is a Gram-positive spherically shaped bacterium, a member of the Bacillota, and is a usual member of the microbiota of the body, frequently found in the upper respiratory tract and on the skin. It is often positive ...
'', or gradually when it is commonly caused by the fungus '' Candida albicans''. The term is from el, παρωνυχία from ''para'' 'around', ''onyx'' 'nail', and the abstract noun suffix '' -ia''. Risk factors include repeatedly washing hands and trauma to the cuticle such as may occur from repeated nail biting or hangnails. Treatment includes antibiotics and antifungals, and if pus is present, the consideration of incision and drainage. Paronychia is commonly misapplied as a synonym for herpetic whitlow or felon.


Definition and etymology

Paronychia is an inflammation of the skin around the nail, which can occur suddenly (acute), when it is usually due to the bacterium ''Staphylococcus aureus'', or gradually (chronic) when it is commonly caused by ''Candida albicans''. The term is from el, παρωνυχία from ''para'', "around", ''onyx'', "nail" and the noun suffix '' -ia''.


Signs and symptoms

The index and middle fingers are most commonly affected and may present with redness, swelling and pain. Pus or discharge may be present. File:Infectionofcutical.JPG, An infection of the cuticle secondary to a splinter Image:MyParonychia.jpg, Left and right ring fingers of the same person: The distal phalanx of the finger on the right exhibits swelling due to acute paronychia. File:ChronicParonychia.jpg, Chronic paronychia


Causes

Acute paronychia is usually caused by bacteria. It is often treated with antibiotics, either topical (applied to the skin) or oral (taken by mouth), or both. Chronic paronychia is most often caused by a yeast infection of the soft tissues around the nail, but can also be traced to a bacterial infection. If the infection is continuous, the cause is often fungal and needs
antifungal An antifungal medication, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis (thrush), serious systemic infections such as crypto ...
cream or paint to be treated. Risk factors include repeatedly washing hands and trauma to the cuticle such as may occur from repeated nail biting or hangnails. In the context of bartending, it is known as "bar rot". Prosector's paronychia is a primary inoculation of tuberculosis of the skin and nails, named after its association with prosectors, who prepare specimens for dissection. Paronychia around the entire nail is sometimes referred to as "runaround paronychia". Painful paronychia in association with a scaly, erythematous, keratotic rash ( papules and plaques) of the ears, nose, fingers, and toes may be indicative of acrokeratosis paraneoplastica, which is associated with squamous-cell
carcinoma Carcinoma is a malignancy that develops from epithelial cells. Specifically, a carcinoma is a cancer that begins in a tissue that lines the inner or outer surfaces of the body, and that arises from cells originating in the endodermal, mesodermal ...
of the
larynx The larynx (), commonly called the voice box, is an organ in the top of the neck involved in breathing, producing sound and protecting the trachea against food aspiration. The opening of larynx into pharynx known as the laryngeal inlet is about ...
. Paronychia can occur with diabetes, drug-induced immunosuppression, or systemic diseases such as pemphigus.


Diagnosis


Types

Paronychia may be divided as occurring suddenly, acute, or gradually, chronic.


Acute

Acute paronychia is an infection of the folds of tissue surrounding the nail of a finger or, less commonly, a toe, lasting less than six weeks. The infection generally starts in the paronychium at the side of the nail, with local redness, swelling, and pain. Acute paronychia is usually caused by direct or indirect trauma to the
cuticle A cuticle (), or cuticula, is any of a variety of tough but flexible, non-mineral outer coverings of an organism, or parts of an organism, that provide protection. Various types of "cuticle" are non- homologous, differing in their origin, structu ...
or nail fold, and may be from relatively minor events, such as dishwashing, an injury from a splinter or thorn, nail biting, biting or picking at a hangnail, finger sucking, an ingrown nail, or manicure procedures.


Chronic

Chronic paronychia is an infection of the folds of tissue surrounding the nail of a finger or, less commonly, a toe, lasting more than six weeks. It is a nail disease prevalent in individuals whose hands or feet are subject to moist local environments, and is often due to contact dermatitis. In chronic paronychia, the cuticle separates from the nail plate, leaving the region between the proximal nail fold and the nail plate vulnerable to infection. It can be the result of dish washing, finger sucking, aggressively trimming the
cuticle A cuticle (), or cuticula, is any of a variety of tough but flexible, non-mineral outer coverings of an organism, or parts of an organism, that provide protection. Various types of "cuticle" are non- homologous, differing in their origin, structu ...
s, or frequent contact with chemicals (mild
alkali In chemistry, an alkali (; from ar, القلوي, al-qaly, lit=ashes of the saltwort) is a basic, ionic salt of an alkali metal or an alkaline earth metal. An alkali can also be defined as a base that dissolves in water. A solution of a ...
s,
acid In computer science, ACID ( atomicity, consistency, isolation, durability) is a set of properties of database transactions intended to guarantee data validity despite errors, power failures, and other mishaps. In the context of databases, a sequ ...
s, etc.). Alternatively, paronychia may be divided as follows: * Candidal paronychia is an inflammation of the nail fold produced by ''C. albicans''. * Pyogenic paronychia is an inflammation of the folds of skin surrounding the nail caused by bacteria. Generally, acute paronychia is pyogenic, as it is usually caused by a bacterial infection.


Differential

Differential diagnosis of paronychia includes: * Cellulitis is a superficial infection and presents as erythema and swelling to the affected portion of the body with no area of fluctuance. Treatment is with oral antibiotics. * Whitlow or felon is a subcutaneous infection of the digital pulp space. The area becomes warm, red, tense, and very painful due to the confinement of the infection, creating pressure in the individual compartments created by the septa of the finger pad. These require excision and drainage, usually with a longitudinal incision and blunt dissection to ensure adequate drainage. * Herpetic whitlow is a viral infection of the distal finger caused by HSV. Patients usually develop a burning, pruritic sensation before the infection erupts. A physical exam shows vesicles and vesicopustules, along with pain and erythema. It is important to not confuse this with a felon or a paronychia as incision and drainage of herpetic whitlow could result in a secondary bacterial infection and failure to heal. * Onychomycosis is a fungal infection of the nail that causes whitish-yellowish discoloration. Sometimes, it is difficult to treat and requires oral antibiotics instead of topical. *
Nail psoriasis Psoriatic onychodystrophy or psoriatic nails is a nail disease. It is common in those with psoriasis, with reported incidences varying from 10% to 78%. Elderly patients and those with psoriatic arthritis are more likely to have psoriatic nails.Ja ...
can affect the fingernails and toenails. It may cause thickening of the nails with areas of pitting, ridges, irregular contour, and even raising of the nail from the nail bed. * Squamous-cell carcinoma is mainly cancer of the skin, but can also affect the nail bed. It is a rare malignant subungual tumor subject to misdiagnosis as chronic paronychia.


Treatment

When no pus is present, warm soaks for acute paronychia are reasonable, though evidence to support its use is lacking. Chronic paronychia is treated by avoiding whatever is causing it, a
topical antifungal An antifungal medication, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis (thrush), serious systemic infections such as cr ...
, and a topical steroid. In those who do not improve following these measures, oral antifungals and steroids may be used or the nail fold may be removed surgically.


Antibiotics

No strong evidence has been found to recommend topical vs. oral antibiotics, and this may be physician-dependent based on experience. Antibiotics used should have ''S. aureus'' coverage. Topical antibiotics used may be a triple antibiotic ointment, bacitracin, or mupirocin. In patients failing topical treatment or more severe cases, oral antibiotics are an option; dicloxacillin or cephalexin can be used. Indications for antibiotics with anaerobic coverage include patients where a concern exists for oral inoculation; this would require the addition of clindamycin or amoxicillin-clavulanate. Antibiotics such as
clindamycin Clindamycin is an antibiotic medication used for the treatment of a number of bacterial infections, including osteomyelitis (bone) or joint infections, pelvic inflammatory disease, strep throat, pneumonia, acute otitis media (middle ear infec ...
or cephalexin are also often used, the first being more effective in areas where MRSA is common. If signs of an
abscess An abscess is a collection of pus that has built up within the tissue of the body. Signs and symptoms of abscesses include redness, pain, warmth, and swelling. The swelling may feel fluid-filled when pressed. The area of redness often extends b ...
(the presence of pus) are seen, drainage is recommended.


Epidemiology

Paronychia is more common in women than in men, by a ratio of three to one. Usually, they affect manual-labor workers or people in occupations that require them to have their hands or feet submerged in water for prolonged periods (e.g., dishwashers). Middle-aged females are at the highest risk of infection. Text was copied from this source, which is available under
Creative Commons Attribution 4.0 International License


References


External links

* {{Disorders of skin appendages Conditions of the skin appendages Occupational diseases Nails (anatomy) Tuberculosis