Proline-serine-threonine phosphatase-interacting protein 1 is an
enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
that in humans is encoded by the ''PSTPIP1''
gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
.
Interactions
PSTPIP1 has been shown to
interact
Advocates for Informed Choice, dba interACT or interACT Advocates for Intersex Youth, is a 501(c)(3) nonprofit organization using innovative strategies to advocate for the legal and human rights of children with intersex traits. The organizati ...
with:
*
Abl gene
Tyrosine-protein kinase ABL1 also known as ABL1 is a protein that, in humans, is encoded by the ''ABL1'' gene (previous symbol ''ABL'') located on chromosome 9. c-Abl is sometimes used to refer to the version of the gene found within the mammalian ...
,
*
BZW1
Basic leucine zipper and W2 domain-containing protein 1 is a protein that in humans is encoded by the ''BZW1'' gene.
Interactions
BZW1 has been shown to interact with PSTPIP1 and CDC5L
Cell division cycle 5-like protein is a protein that in h ...
,
*
CD2
CD2 (cluster of differentiation 2) is a cell adhesion molecule found on the surface of T cells and natural killer (NK) cells.
It has also been called T-cell surface antigen T11/Leu-5, LFA-2, LFA-3 receptor, erythrocyte receptor and rosette rece ...
,
[
* ]PTPN12
Tyrosine-protein phosphatase non-receptor type 12 is an enzyme that in humans is encoded by the ''PTPN12'' gene.
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecul ...
,PTPN18
Tyrosine-protein phosphatase non-receptor type 18 is an enzyme that in humans is encoded by the ''PTPN18'' gene.
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecule ...
,
See also
* PAPA syndrome
PAPA syndrome is an acronym for pyogenic arthritis, pyoderma gangrenosum and acne. It is a rare genetic disorder characterised by its effects on skin and joints.
Signs and symptoms
PAPA syndrome usually begins with arthritis at a young age, with ...
References
Further reading
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