''Tectiviridae'' is a family of

viruses A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1 ...

with 10 species in five genera. Bacteria serve as natural hosts. Tectiviruses have no head-tail structure, but are capable of producing tail-like tubes of ~ 60×10 nm upon adsorption or after

chloroform Chloroform, or trichloromethane, is an organic compound with chemical formula, formula Carbon, CHydrogen, HChlorine, Cl3 and a common organic solvent. It is a colorless, strong-smelling, dense liquid produced on a large scale as a precursor to ...

treatment. The name is derived from

Latin Latin (, or , ) is a classical language belonging to the Italic branch of the Indo-European languages. Latin was originally a dialect spoken in the lower Tiber area (then known as Latium) around present-day Rome, but through the power of the ...

''tectus'' (meaning 'covered').

Virology

The

virion A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1 ...

s of ''Tectiviridae'' species are non-enveloped, icosahedral and display a pseudo T=25 symmetry. The

capsid A capsid is the protein shell of a virus, enclosing its genetic material. It consists of several oligomeric (repeating) structural subunits made of protein called protomers. The observable 3-dimensional morphological subunits, which may or may ...

has two layers. The outer layer is a protein structure of 240 capsid proteins trimers, and the inner one is a proteinaceous lipid membrane which envelopes the virus

genome In the fields of molecular biology and genetics, a genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding ge ...

. Apical spikes extending about 20

nanometers 330px, Different lengths as in respect to the molecular scale. The nanometre (international spelling as used by the International Bureau of Weights and Measures; SI symbol: nm) or nanometer (American and British English spelling differences#-re ...

(nm) protrude from the icosahedrons vertices. The genome is a single molecule of linear double-stranded DNA of 15 kilo bases in length, and has 30 open reading frames. It forms a tightly packed coil and encodes several structural proteins. It encodes about 30 proteins that are transcribed in operons. At least 9 structural proteins are present in the viron. The genome is about 66 mega

Dalton Dalton may refer to: Science * Dalton (crater), a lunar crater * Dalton (program), chemistry software * Dalton (unit) (Da), the atomic mass unit * John Dalton, chemist, physicist and meteorologist Entertainment * Dalton (Buffyverse), minor cha ...

s in weight and constitutes 14–15% of the virion by weight.

Lipid Lipids are a broad group of naturally-occurring molecules which includes fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, and others. The functions of lipids include ...

s constitute a further 15% by weight.

Carbohydrates In organic chemistry, a carbohydrate () is a biomolecule consisting of carbon (C), hydrogen (H) and oxygen (O) atoms, usually with a hydrogen–oxygen atom ratio of 2:1 (as in water) and thus with the empirical formula (where ''m'' may or may ...

are not present.

Life cycle

Viral replication is cytoplasmic. Entry into the host cell is achieved by adsorption into the host cell. After adsorption to the host cell surface the virion extrudes a tail-tube structure through a vertex for genome delivery into the host. Replication follows the DNA strand displacement model. DNA-templated transcription is the method of transcription. Capsid proteins polymerize around a lipoprotein vesicle translocated in the cytoplasm by virion assembly factors. Mature virons are released by lysis, which, in the case of PRD1, is achieved with the aid of virus-encoded lysis machinery consisting of four proteins: P15 (

endolysin Lysins, also known as endolysins or murein hydrolases, are hydrolytic enzymes produced by bacteriophages in order to cleave the host's cell wall during the final stage of the lytic cycle. Lysins are highly evolved enzymes that are able to target ...

), P35 (holin), P36 and P37 (homologues of the Rz/Rz1 proteins of phage lambda).

Taxonomy

''Tectiviridae'' contains the following genera and species: * '' Alphatectivirus'' ** '' Pseudomonas virus PR4'' ** ''

Pseudomonas virus PRD1 ''Pseudomonas'' is a genus of Gram-negative, Gammaproteobacteria, belonging to the family Pseudomonadaceae and containing 191 described species. The members of the genus demonstrate a great deal of metabolic diversity and consequently are able to ...

'' * '' Betatectivirus'' ** '' Bacillus virus AP50'' ** '' Bacillus virus Bam35'' ** ''

Bacillus virus GIL16 ''Bacillus'' (Latin "stick") is a genus of Gram-positive, rod-shaped bacteria, a member of the phylum ''Bacillota'', with 266 named species. The term is also used to describe the shape (rod) of other so-shaped bacteria; and the plural ''Bacilli ...

'' ** ''

Bacillus virus Wip1 ''Bacillus'' (Latin "stick") is a genus of Gram-positive, rod-shaped bacteria, a member of the phylum ''Bacillota'', with 266 named species. The term is also used to describe the shape (rod) of other so-shaped bacteria; and the plural ''Bacilli ...

'' * '' Deltatectivirus'' ** ''

Streptomyces virus Forthebois ''Streptomyces'' is the largest genus of Actinomycetota and the type genus of the family Streptomycetaceae. Over 500 species of ''Streptomyces'' bacteria have been described. As with the other Actinomycetota, streptomycetes are gram-positive, ...

'' ** ''

Streptomyces virus WheeHeim ''Streptomyces'' is the largest genus of Actinomycetota and the type genus of the family Streptomycetaceae. Over 500 species of ''Streptomyces'' bacteria have been described. As with the other Actinomycetota, streptomycetes are gram-positive, ...

'' * '' Epsilontectivirus'' ** ''

Rhodococcus virus Toil ''Rhodococcus'' is a genus of aerobic, nonsporulating, nonmotile Gram-positive bacteria closely related to ''Mycobacterium'' and ''Corynebacterium''. While a few species are pathogenic, most are benign, and have been found to thrive in a broad ...

'' * '' Gammatectivirus'' ** ''

Gluconobacter virus GC1 ''Gluconobacter'' is a genus of bacteria in the acetic acid bacteria family. They prefer sugar-rich environments, so are sometimes found as a spoilage organism in beer. They are not known to be pathogenic but can cause rot in apples and pears ...

'' Other unassigned phages:Unclassified Tectiviridae
NCBI Taxonomy. * ''

Thermus virus phiKo ''Thermus'' is a genus of thermophilic bacteria. It is one of several bacteria belonging to the ''Deinococcota'' phylum. ''Thermus'' species can be distinguished from other genera in the family ''Thermaceae'' as well as all other bacteria by th ...

'' * '' Microbacterium virus Badulia'' * '' Microbacterium virus MuffinTheCat''

References

External links

ICTV
{{Taxonbar, from=Q569755 Bacteriophages

Virology

Life cycle

Taxonomy

References

Further reading

External links