In Ohio, State Route 80 may refer to:
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Interstate 80
Interstate 80 (I-80) is an east–west transcontinental freeway that crosses the United States from downtown San Francisco, California, to Teaneck, New Jersey, in the New York metropolitan area. The highway was designated in 1956 as one o ...
, the only Ohio highway numbered 80 since 1962
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Ohio State Route 183, known as SR 80 from 1923 to 1962
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Ohio State Route 700
State Route 700 (SR 700) is a long north–south state highway in the northeastern portion of the U.S. state of Ohio. The southern terminus of SR 700 is at SR 88 in Freedom Township, about south of Hiram. Its northe ...
, part of SR 80 from 1923 to 1942
{{Road disambiguation