Ntshangase is a South African surname. Notable people with the surname include:
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Luyanda Ntshangase (1997–2018), South African football player
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Phumlani Ntshangase (born 1994), South African football midfielder
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Siphelele Ntshangase (born 1993), South African football player
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Bridget Ntshangase (died 2021), South African politician
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Surnames of African origin