Neil Kelleher (scientist)
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Neil L. Kelleher is the Walter and Mary Elizabeth Glass Professor of
Chemistry Chemistry is the science, scientific study of the properties and behavior of matter. It is a natural science that covers the Chemical element, elements that make up matter to the chemical compound, compounds made of atoms, molecules and ions ...
, Molecular Biosciences, and
Medicine Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care pract ...
at
Northwestern University Northwestern University is a private research university in Evanston, Illinois. Founded in 1851, Northwestern is the oldest chartered university in Illinois and is ranked among the most prestigious academic institutions in the world. Charte ...
. His research focuses on
mass spectrometry Mass spectrometry (MS) is an analytical technique that is used to measure the mass-to-charge ratio of ions. The results are presented as a ''mass spectrum'', a plot of intensity as a function of the mass-to-charge ratio. Mass spectrometry is use ...
, primarily its application to
proteomics Proteomics is the large-scale study of proteins. Proteins are vital parts of living organisms, with many functions such as the formation of structural fibers of muscle tissue, enzymatic digestion of food, or synthesis and replication of DNA. In ...
. He is known mainly for
top-down proteomics Top-down proteomics is a method of protein identification that either uses an ion trapping mass spectrometer to store an isolated protein ion for mass measurement and tandem mass spectrometry (MS/MS) analysis or other protein purification methods ...
and the development of the fragmentation technique of
electron-capture dissociation Electron-capture dissociation (ECD) is a method of fragmenting gas-phase ions for structure elucidation of peptides and proteins in tandem mass spectrometry. It is one of the most widely used techniques for activation and dissociation of mass sel ...
with
Roman Zubarev Roman A. Zubarev is a professor of medicinal proteomics in the Department of Medical Biochemistry and Biophysics at the Karolinska Institutet. His research focuses on the use of mass spectrometry in biology and medicine. Early life and educati ...
while in
Fred McLafferty Fred Warren McLafferty (May 11, 1923 − December 26, 2021) was an American chemist known for his work in mass spectrometry. He is best known for the McLafferty rearrangement reaction that was observed with mass spectrometry. With Roland Gohlk ...
's lab at
Cornell University Cornell University is a private statutory land-grant research university based in Ithaca, New York. It is a member of the Ivy League. Founded in 1865 by Ezra Cornell and Andrew Dickson White, Cornell was founded with the intention to teach an ...
.


Early life and education

* B.S.
Pacific Lutheran University Pacific Lutheran University (PLU) is a private Lutheran university in Parkland, Washington. It was founded by Norwegian Lutheran immigrants in 1890. PLU is sponsored by the 580 congregations of Region I of the Evangelical Lutheran Church in Ame ...
* M.S. and Ph.D.
Cornell University Cornell University is a private statutory land-grant research university based in Ithaca, New York. It is a member of the Ivy League. Founded in 1865 by Ezra Cornell and Andrew Dickson White, Cornell was founded with the intention to teach an ...


Research interests

*
Mass spectrometry Mass spectrometry (MS) is an analytical technique that is used to measure the mass-to-charge ratio of ions. The results are presented as a ''mass spectrum'', a plot of intensity as a function of the mass-to-charge ratio. Mass spectrometry is use ...
*
Electron-capture dissociation Electron-capture dissociation (ECD) is a method of fragmenting gas-phase ions for structure elucidation of peptides and proteins in tandem mass spectrometry. It is one of the most widely used techniques for activation and dissociation of mass sel ...
*
Proteomics Proteomics is the large-scale study of proteins. Proteins are vital parts of living organisms, with many functions such as the formation of structural fibers of muscle tissue, enzymatic digestion of food, or synthesis and replication of DNA. In ...
**
Top-down proteomics Top-down proteomics is a method of protein identification that either uses an ion trapping mass spectrometer to store an isolated protein ion for mass measurement and tandem mass spectrometry (MS/MS) analysis or other protein purification methods ...


Awards

* Biemann Medal, 2009 * Pittsburgh Conference Achievement Award, 2008 *
Pfizer Award in Enzyme Chemistry The Pfizer Award in Enzyme Chemistry, formerly known as the Paul-Lewis Award in Enzyme Chemistry was established in 1945. Consisting of a gold medal and honorarium, its purpose is to stimulate fundamental research in enzyme chemistry by scientists ...
(American Chemical Society, Division of Biological Chemistry), 2006 * A.F. Findeis Award in Measurement Science (American Chemical Society, Division of Analytical Chemistry), 2006 *
Beckman Fellow A Beckman Fellow receives funding, usually via an intermediary institution, from the Arnold and Mabel Beckman Foundation, founded by Arnold Orville Beckman and his wife Mabel. The Foundation supports programs at several institutions to encourage re ...
, 2002-2003 * Presidential Early Career Award * Alfred P. Sloan Fellow * Packard Fellow * NSF CAREER Award * Lilly Analytical Chemistry Award * Burroughs Wellcome Fund Young Investigator * Searle Scholar * Fulbright Scholar


References


External links


Kelleher Group Website
Pacific Lutheran University alumni Cornell University alumni Northwestern University faculty 21st-century American chemists Mass spectrometrists Living people 1970 births Harvard University people {{US-academic-scientist-stub