Neurotrimin is a

protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...

that in humans is encoded by the ''NTM''

gene In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...

. This

encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of

immunoglobulin An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein used by the immune system to identify and neutralize foreign objects such as pathogenic bacteria and viruses. The antibody recognizes a unique molecule of the ...

(Ig) domain-containing

glycosylphosphatidylinositol Glycosylphosphatidylinositol (), or glycophosphatidylinositol, or GPI in short, is a phosphoglyceride that can be attached to the C-terminus of a protein during posttranslational modification. The resulting GPI-anchored proteins play key roles in ...

(GPI)-anchored cell adhesion molecules. The encoded

may promote

neurite A neurite or neuronal process refers to any projection from the cell body of a neuron. This projection can be either an axon or a dendrite. The term is frequently used when speaking of immature or developing neurons, especially of cells in culture ...

outgrowth and adhesion via a

homophilic Terms used to describe homosexuality have gone through many changes since the emergence of the first terms in the mid-19th century. In English, some terms in widespread use have been sodomite, Achillean, Sapphic, Uranian, homophile, lesbian, ...

mechanism. This gene is closely linked to a related family member,

opioid Opioids are substances that act on opioid receptors to produce morphine-like effects. Medically they are primarily used for pain relief, including anesthesia. Other medical uses include suppression of diarrhea, replacement therapy for opioid us ...

binding protein/cell adhesion molecule-like (

OPCML Opioid-binding protein/cell adhesion molecule is a protein that in humans is encoded by the ''OPCML'' gene. This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily. The encoded protein is localized in the cell ...

) on chromosome 11. Multiple alternatively spliced variants have been found but only two variants have had their full-length sequences determined.

References

Further reading