Michael Lesch (actor)
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Michael Lesch (June 30, 1939 – March 19, 2008) was a
Jewish American American Jews or Jewish Americans are American citizens who are Jewish, whether by religion, ethnicity, culture, or nationality. Today the Jewish community in the United States consists primarily of Ashkenazi Jews, who descend from diaspora Je ...
physician and medical educator who helped identify an important genetic disorder associated with retardation and self-mutilation. This disease is now known as the
Lesch–Nyhan syndrome Lesch–Nyhan syndrome (LNS) is a rare inherited disorder caused by a deficiency of the enzyme hypoxanthine-guanine phosphoribosyltransferase (HGPRT). This deficiency occurs due to mutations in the ''HPRT1'' gene located on the X chromosome. LNS ...
. In the mid-1960s when the
syndrome A syndrome is a set of medical signs and symptoms which are correlated with each other and often associated with a particular disease or disorder. The word derives from the Greek σύνδρομον, meaning "concurrence". When a syndrome is paired ...
was discovered, Lesch was a research associate working at the Laboratory of General and Comparative Biochemistry at the NIH National Institute of Mental Health in Bethesda, Maryland.
William Nyhan William Leo Nyhan (born March 13, 1926) is an American physician best known as the co-discoverer of Lesch–Nyhan syndrome. Nyhan currently serves as professor of pediatrics at UC San Diego School of Medicine in La Jolla, California. He has he ...
, a pediatrician and biochemical geneticist, was his mentor. Lesch was 30 years old when he discovered the disease. Lesch completed his medical training at
Johns Hopkins Johns Hopkins (May 19, 1795 – December 24, 1873) was an American merchant, investor, and philanthropist. Born on a plantation, he left his home to start a career at the age of 17, and settled in Baltimore, Maryland where he remained for most ...
in the Osler Medical Service in 1964. While at Hopkins he earned the distinguished honor of President,
Alpha Omega Alpha Alpha Omega Alpha Honor Medical Society () is an honor society in the field of medicine. Alpha Omega Alpha currently has active Chapters in 132 LCME- accredited medical schools in the United States and Lebanon. It annually elects over 4,000 new ...
, The Johns Hopkins University Chapter.


Biography

Michael Lesch was born in 1939 in
Queens Queens is a borough of New York City, coextensive with Queens County, in the U.S. state of New York. Located on Long Island, it is the largest New York City borough by area. It is bordered by the borough of Brooklyn at the western tip of Long ...
in
New York City New York, often called New York City or NYC, is the List of United States cities by population, most populous city in the United States. With a 2020 population of 8,804,190 distributed over , New York City is also the L ...
. He attended
Columbia University Columbia University (also known as Columbia, and officially as Columbia University in the City of New York) is a private research university in New York City. Established in 1754 as King's College on the grounds of Trinity Church in Manhatt ...
, attaining
Phi Beta Kappa The Phi Beta Kappa Society () is the oldest academic honor society in the United States, and the most prestigious, due in part to its long history and academic selectivity. Phi Beta Kappa aims to promote and advocate excellence in the liberal a ...
during his junior year and graduating
summa cum laude Latin honors are a system of Latin phrases used in some colleges and universities to indicate the level of distinction with which an academic degree has been earned. The system is primarily used in the United States. It is also used in some Sou ...
, before entering medical school at
Johns Hopkins School of Medicine The Johns Hopkins University School of Medicine (JHUSOM) is the medical school of Johns Hopkins University, a private research university in Baltimore, Maryland. Founded in 1893, the School of Medicine shares a campus with the Johns Hopkins Hospi ...
. After receiving his medical degree, Lesch became an internist and specialized in
cardiology Cardiology () is a branch of medicine that deals with disorders of the heart and the cardiovascular system. The field includes medical diagnosis and treatment of congenital heart defects, coronary artery disease, heart failure, valvular heart d ...
. In the 1970s Lesch distinguished himself early on in Boston, Massachusetts, at the
Peter Bent Brigham Hospital Brigham and Women's Hospital (BWH) is the second largest teaching hospital of Harvard Medical School and the largest hospital in the Longwood Medical Area in Boston, Massachusetts. Along with Massachusetts General Hospital, it is one of the two fo ...
and the
Harvard Medical School Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consi ...
. In 1971-72 he was appointed Chief Resident at the Brigham Hospital. Between the years of 1974–1976, he became an Associate Professor of Medicine at the Harvard Medical School and the Director of the S.A. Levine Cardiac Center at the Peter Bent Brigham Hospital. In 1976, he moved with his family from Boston to Chicago, where he took the position of Chief, Section of Cardiology, Northwestern University Medical School, Northwestern Memorial Hospital, Chicago, Illinois, a position he held for 12 years. At age 37, he was one of the youngest Section Chiefs ever appointed at Northwestern in the Department of Cardiology. During his tenure in Chicago, he held the position of Vice President of the Chicago Heart Association from 1978–80. From 1982-1983 he was the President of the Chicago Heart Association. In 1982 he was also listed for the first time in the Annuals of Who's Who in America. In 1983–85, he was appointed to the Board of Trustees, University Space Research Association (NASA). From 1984–87, Lesch was asked to Chair the Chicago Heart Association's Cardiac Exhibition Committee at the Chicago Museum of Science and Industry. That Committee developed a four-chamber heart that museum visitors could walk-thru to better understand the heart's physiology. In 1988, Lesch was awarded The Heart of the Year Award, from the Metropolitan Chicago Chapter of the American Heart Association. In 1989, Lesch moved to Michigan, where he became Chairman of the Department of Medicine at the Henry Ford Hospital and Health System until 1998. In 1993 he was appointed to the Board of Trustees at the Henry Ford Hospital. In 1998, Lesch was named chairman of Department of Medicine at St. Luke's-Roosevelt Hospital Center (now
Mount Sinai Morningside Mount Sinai Morningside, formerly known as Mount Sinai St. Luke's, is a teaching hospital located in the Morningside Heights neighborhood of Manhattan in New York City. It is affiliated with the Icahn School of Medicine at Mount Sinai and the ...
) in New York City and Professor of Medicine there at the Columbia University College of Physicians and Surgeons. A position he held until his death in 2008. In 1999 he was appointed to the Board of Trustees, St. Luke's-Roosevelt Hospital Center and in 2002 he became the Medical Director for the Cardiac Service Line at Continuum Health Partners. During his career, Lesch lectured and taught extensively as a visiting professor abroad. In 1977 he was a visiting Professor of Cardiology at the Sree Chitra Tirunal Medical Center in Trivandrum, India. In 1984 he was an invited lecturer at the International Symposium on Stress and Heart Disease in Winnipeg, Canada. In 1986 Dr Lesch became a Fulbright Visiting Professor of Cardiology at the Egyptian Cardiology Society and a Fulbright Visiting Professor of Cardiology, at the Portuguese Society of Cardiology. That same year, Lesch was named an Honorary Member of the Portuguese Society of Cardiology. In 1993, Lesch was a visiting Professor of Cardiology at the Universidad Peruana Cayetano Heredia in Lima, Peru. In 1999, Lesch was a visiting Cardiologist at the Sakakibara Heart Institute in Tokyo, Japan. And in 2000, he was a Visiting Professor of Cardiology, at the Tohoku University School of Medicine in Sendai, Japan. Lesch earned the distinction of being listed in the annals of The Best Doctors in America starting in 2003, an honor he retained every year until his death. Lesch was a prolific writer, publisher and editor. From 1971 until his death, he was the co-editor of the periodical, Progress in Cardiovascular Diseases. From 1975-76 he was an Associate Editor at The New England Journal of Medicine. From 1976-79 he was on the Editorial Board of Cardiovascular Medicine. From 1978-82 he was on the Editorial Board of the American Journal of Cardiology. From 1980-92 he was on the Editorial Board of American Heart Journal. From 1987-96 he was on the Editorial Board of the American Journal of Cardiac Imaging. From 1996 until his death, he was on the Editorial Board, American Journal of Geriatric Cardiology. Lesch was also an avid fly fisherman who fished the lakes and rivers of Canada, Alaska, Chile, the Arctic, the Amazon and Argentina. Lesch died unexpectedly in his sleep while in
Argentina Argentina (), officially the Argentine Republic ( es, link=no, República Argentina), is a country in the southern half of South America. Argentina covers an area of , making it the second-largest country in South America after Brazil, th ...
on a fishing trip to the
Gallegos River The Gallegos River () is a river in the Argentine province of Santa Cruz, on whose estuary lies Río Gallegos city, capital of the province. Given that its basin reaches only the fringes of the Andes mountains it classifies as a sub-Andean rive ...
. He is survived by his wife, Bella Lesch, two children (Leah Lesch and Ian Lesch) and six grandchildren.


References


External links

*
Obituary for Michael Lesch
by Lawrence K. Altman in
The New York Times ''The New York Times'' (''the Times'', ''NYT'', or the Gray Lady) is a daily newspaper based in New York City with a worldwide readership reported in 2020 to comprise a declining 840,000 paid print subscribers, and a growing 6 million paid ...
{{DEFAULTSORT:Lesch, Michael American cardiologists 1939 births 2008 deaths Fellows of the American College of Cardiology