Companies
* McCain Foods Limited, a producer of frozen foods * McCain, Inc., privately held American manufacturing company headquartered in Vista, CA * McCain Institute, Washington, D.C.-based think tankPlaces
* McCain Bluff, in the Usarp Mountains of Antarctica * McCain Furniture Store, historic building in downtown Columbia, Missouri, United States * McCain Mall, enclosed shopping mall in North Little Rock, Arkansas, United States *Other uses
* USS ''John S. McCain'', two ships of the United States NavySee also
* Cain, one of the sons of Adam and Eve * Caine (disambiguation) * McAnn, a surname {{disambiguation