Munc-13 (an

acronym An acronym is a word or name formed from the initial components of a longer name or phrase. Acronyms are usually formed from the initial letters of words, as in ''NATO'' (''North Atlantic Treaty Organization''), but sometimes use syllables, as ...

for mammalian uncoordinated-13) is a protein which complexes with RIM and likely comprises part of cellular structure which anchors

synaptic vesicle In a neuron, synaptic vesicles (or neurotransmitter vesicles) store various neurotransmitters that are released at the synapse. The release is regulated by a voltage-dependent calcium channel. Vesicles are essential for propagating nerve impulse ...

s. Its activation by DAG seems to be important for maintaining high rate of synaptic release during prolonged repetitive stimulation.

References

Proteins Secretory vesicles Neurophysiology {{Protein-stub