Miltenyi Biotec is a global

biotechnology Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used ...

company headquartered near Cologne in Bergisch Gladbach, Germany. The company is a provider of products and services that support scientists, clinical researchers, and physicians across basic research,

translational research Translational research (also called translation research, translational science, or, when the context is clear, simply translation) is research aimed at translating (converting) results in basic research into results that directly benefit humans. ...

, and clinical applications. The company offers solutions covering techniques of sample preparation,

cell Cell most often refers to: * Cell (biology), the functional basic unit of life Cell may also refer to: Locations * Monastic cell, a small room, hut, or cave in which a religious recluse lives, alternatively the small precursor of a monastery ...

separation, cell sorting, flow cytometry, cell culture, molecular analysis, clinical applications and

small animal imaging Preclinical imaging is the visualization of living animals for research purposes, such as drug development. Imaging modalities have long been crucial to the researcher in observing changes, either at the organ, tissue, cell, or molecular level, i ...

. Miltenyi Biotec has more than 3,000 employees in 28 countries and more than 17,000 products.

Products

Miltenyi Biotec products have been cited in more than 20,000 publications and used in more than 35.000 clinical treatments to date. Many of the publications that have cited Miltenyi Biotec products can be accessed through

CiteAb CiteAb Limited is a life science data company located in Bath, England that offers an antibody, biochemicals, experimental models, kits and protein search tool to aid biomedical scientists in their research. History and operations CiteAb st ...

, an antibody search engine which lists 4591 Miltenyi Biotec products. Miltenyi Biotec instruments,

reagents In chemistry, a reagent ( ) or analytical reagent is a substance or compound added to a system to cause a chemical reaction, or test if one occurs. The terms ''reactant'' and ''reagent'' are often used interchangeably, but reactant specifies a ...

and services support basic research, clinical research, and the translation of basic research findings into clinical applications that enhance human health and treat severe disease. Its product portfolio addresses a complete range of techniques from bench to bedside. Services offered by Miltenyi Biotec include gene expression analysis and contract production of biologicals according to GMP guidelines. Miltenyi Biotec technologies are used in applications concerned with accessing, analyzing, and utilizing primary and primary-derived cells – across basic research, translational research, and clinical applications. Examples of these applications include sample preparation, cell separation, cell sorting, flow cytometry, molecular applications, cell culture up to GMP grade, preclinical imaging, clinical-grade cell preservation, and clinical-scale cell processing. The company’s reagents and devices are used primarily in the research areas of

immunology Immunology is a branch of medicineImmunology for Medical Students, Roderick Nairn, Matthew Helbert, Mosby, 2007 and biology that covers the medical study of immune systems in humans, animals, plants and sapient species. In such we can see the ...

, stem cell biology,

neuroscience Neuroscience is the scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions and disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, developme ...

and

cancer Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal b ...

Sample Preparation

Miltenyi Biotec offers instruments, tools and reagents to facilitate sample preparation.

Application areas

Miltenyi Biotec products are used commonly in the application areas of immunology, stem cell biology, neuroscience and cancer. Their products are used from basic research to clinical applications and are designed to support the successful translation of findings into practical applications that enhance human health and well being. Enabling translational research is a major mission of the company, as is advancing cellular therapy. The company’s products aim to support the development of cellular therapies and make cellular therapy a more viable reality for more patients.

History

* 1989 – Stefan Miltenyi invents magnetic-activated cell separation * 1990 – Miltenyi Biotec patents MACS Technology * 1992 – Miltenyi Biotec opens its U.S. subsidiary * 1995 – Miltenyi Biotec opens its UK subsidiary * 1998 – Miltenyi Biotec opens its France, Italy and Spain subsidiaries * 2001 – Miltenyi Biotec opens its China location * 2002 – Miltenyi Biotec acquires the plasma absorber technology developed by PlasmaSelect AG and markets the products under the trademark TheraSorb * 2002 – Miltenyi Biotec opens its Australia subsidiary * 2003 – Miltenyi Biotec opens its

GMP GMP may refer to: Finance and economics * Gross metropolitan product * Guaranteed maximum price * Guaranteed Minimum Pension Science and technology * GNU Multiple Precision Arithmetic Library, a software library * Granulocyte-macrophage progenito ...

facility in

Teterow Teterow () is a town of Germany, in the district of Rostock, in Mecklenburg-Western Pomerania. It is the geographical center of this federal state. It had a population of 8,852 in 2011. History The ''Stadtkirche St. Peter und Paul'' (St. Pete ...

, Germany * 2003 – Miltenyi Biotec opens its Japan and Singapore subsidiaries * 2003 – Miltenyi Biotec acquires Memorec Biotec GmbH * 2004 – Miltenyi Biotec opens its Benelux subsidiary in the Netherlands * 2008 – Miltenyi Biotec acquires Medic Tools AG * 2008 – Miltenyi Biotec launches its autoMACS Pro Separator cell separation instrument * 2008 – Miltenyi Biotec launches its MACSQuant Analyzer flow cytometry instrument * 2011 – Miltenyi Biotec acquires Coley Pharmaceutical Group * 2011 – Miltenyi Biotec partners with TeutoCell to develop novel cell culture techniques * 2012 – Miltenyi Biotec opens its Nordic subsidiary in Sweden * 2012 – Miltenyi Biotec opens its Korea subsidiary in Seoul,

South Korea South Korea, officially the Republic of Korea (ROK), is a country in East Asia, constituting the southern part of the Korean Peninsula and sharing a land border with North Korea. Its western border is formed by the Yellow Sea, while its eas ...

* 2013 – Miltenyi Biotec acquires Owl biomedical, adding to their portfolio new microchip-based cell sorting technology * 2014 – Miltenyi Biotec receives

FDA The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food ...

approval for CliniMACS® CD34 Reagent System for prevention of graft-versus-host disease in the treatment of acute myeloid leukemia * 2014 – Miltenyi Biotec acquires gene therapy assets from Lentigen Corporation * 2017 – Acquisition of imaging specialist Sensovation AG * 2018 – Acquisition of microscopy specialist LaVision BioTec

Structure

Miltenyi Biotec is a limited liability company (referred to as GmbH in Germany). The officers of the company are Stefan Miltenyi (Founder and President), Dr. Boris Stoffel, Norbert Hentschel, Dr. Juergen Schmitz, Dr. Anoon Overstijns. Headquartered in Bergisch Gladbach with a

facility in Teterow, Germany, Miltenyi Biotec also has locations in the United States (two GMP facilities), Great Britain, France, Belgium, Italy, Spain, China, Australia, Japan, The Netherlands, Singapore and Sweden. The company has more than 3,500 employees worldwide (approx. 800 in the United States). The North American Divisions are supported by Miltenyi Biotec North America, which provides all central services to the North American Divisions.

Controversies

In March 2022, citing

Russian Invasion of Ukraine On 24 February 2022, in a major escalation of the Russo-Ukrainian War, which began in 2014. The invasion has resulted in tens of thousands of deaths on both sides. It has caused Europe's largest refugee crisis since World War II. An ...

as the reason, Miltenyi Biotec suspended supplies of CAR-T therapy equipment to Russian Rogachev children's hospital, leaving patients with incurable tumors for which all other possibilities have been exhausted with no treatment options. According to , director of the Institute of Hematology, Immunology and Cell Technologies of the National Medical Research Center, it will lead to their death. While the treatment was available, 90% of child patients were achieving remission, with at least 54 lives saved since 2018.

References

{{Authority control Biotechnology companies established in 1989 Biotechnology companies of Germany Companies based in North Rhine-Westphalia 1989 establishments in West Germany German companies established in 1989