Mike Shaw (heart Operation Patient)
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Clarence Walton Lillehei (October 23, 1918 – July 5, 1999), was an American surgeon who pioneered
open-heart surgery Cardiac surgery, or cardiovascular surgery, is surgery on the heart or great vessels performed by cardiac surgeons. It is often used to treat complications of ischemic heart disease (for example, with coronary artery bypass grafting); to corr ...
, as well as numerous techniques, equipment and prostheses for cardiothoracic surgery.


Background

Clarence (often called "Walt") Lillehei was born in
Minneapolis, Minnesota Minneapolis () is the largest city in Minnesota, United States, and the county seat of Hennepin County. The city is abundant in water, with thirteen lakes, wetlands, the Mississippi River, creeks and waterfalls. Minneapolis has its origins ...
, the son of Dr. Clarence Ingvald Lillehei (1892-1973) and Elizabeth Lillian (Walton) Lillehei (1891-1973). He attended West High School in Minneapolis in 1935. He attended the University of Minnesota at the age of 17. He earned 4 degrees at the
University of Minnesota The University of Minnesota, formally the University of Minnesota, Twin Cities, (UMN Twin Cities, the U of M, or Minnesota) is a public university, public Land-grant university, land-grant research university in the Minneapolis–Saint Paul, Tw ...
, including his
B.S. A Bachelor of Science (BS, BSc, SB, or ScB; from the Latin ') is a bachelor's degree awarded for programs that generally last three to five years. The first university to admit a student to the degree of Bachelor of Science was the University of ...
(with distinction) in 1939, his
M.D. Doctor of Medicine (abbreviated M.D., from the Latin ''Medicinae Doctor'') is a medical degree, the meaning of which varies between different jurisdictions. In the United States, and some other countries, the M.D. denotes a professional degree. T ...
(
Alpha Omega Alpha Alpha Omega Alpha Honor Medical Society () is an honor society in the field of medicine. Alpha Omega Alpha currently has active Chapters in 132 LCME- accredited medical schools in the United States and Lebanon. It annually elects over 4,000 new ...
) in 1942, his
M.S. A Master of Science ( la, Magisterii Scientiae; abbreviated MS, M.S., MSc, M.Sc., SM, S.M., ScM or Sc.M.) is a master's degree in the field of science awarded by universities in many countries or a person holding such a degree. In contrast to ...
in
physiology Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemical ...
in 1951, and his
Ph.D. A Doctor of Philosophy (PhD, Ph.D., or DPhil; Latin: or ') is the most common degree at the highest academic level awarded following a course of study. PhDs are awarded for programs across the whole breadth of academic fields. Because it is a ...
in
surgery Surgery ''cheirourgikē'' (composed of χείρ, "hand", and ἔργον, "work"), via la, chirurgiae, meaning "hand work". is a medical specialty that uses operative manual and instrumental techniques on a person to investigate or treat a pat ...
in 1951.


Career

In 1944, Alfred Blalock at
Johns Hopkins University Hospital The Johns Hopkins Hospital (JHH) is the teaching hospital and biomedical research facility of the Johns Hopkins School of Medicine, located in Baltimore, Maryland, U.S. It was founded in 1889 using money from a bequest of over $7 million (1873 mo ...
had begun successfully performing surgery on the great vessels around the heart to relieve the symptoms of tetralogy of Fallot, demonstrating that heart surgery could be possible. Lillehei participated in the first successful surgical repair of the heart on 2 September 1952. That historic operation, using
hypothermia Hypothermia is defined as a body core temperature below in humans. Symptoms depend on the temperature. In mild hypothermia, there is shivering and mental confusion. In moderate hypothermia, shivering stops and confusion increases. In severe h ...
, was led by his longtime friend and colleague,
F. John Lewis Floyd John Lewis (1916 – September 20, 1993) was an American surgeon who performed the first successful open heart operation, closing an atrial septal defect in a 5-year-old girl, on 2 September 1952. For the next 3 years, Lewis and colleagues ...
. Lillehei was a professor in the Department of Surgery at the University of Minnesota from 1951 to 1967. However, hypothermia, gave only a relatively brief time, up to 10 minutes, during which surgery could be performed and was therefore not suited for complex
congenital defects A birth defect, also known as a congenital disorder, is an abnormal condition that is present at birth regardless of its cause. Birth defects may result in disabilities that may be physical, intellectual, or developmental. The disabilities can r ...
within the heart. To resolve this problem, Lillehei performed operations using cross-circulation, in which a donor was hooked up nearby to take up the pumping and oxygenation functions of the patient who was being operated on. Using this technique, Lillehei led the team that performed successful repair of a ventricular septal defect on March 26, 1954. Although the repair was successful, the patient, 13-month-old Gregory Glidden, died 11 days later of suspected
pneumonia Pneumonia is an inflammatory condition of the lung primarily affecting the small air sacs known as alveoli. Symptoms typically include some combination of productive or dry cough, chest pain, fever, and difficulty breathing. The severity ...
. Lillehei and his team continued to use cross-circulation for a total of 44 open-heart operations in the following year, of which 32 patients survived. These operations included the first repairs of the atrioventricular canal and tetralogy of Fallot. In July of that year, a successful operation was performed on patient Michael Eugene Shaw of Litchfield, Minnesota. Lillehei cooperated with Professor
Moshe Gueron Moshe Yitzhak Gueron ( he, משה יצחק גרון; b. 20 March 1926 - 11 December 2017) was an Israeli physician and researcher, innovator, scientist, medical educator, Professor of Cardiology at the Medical School for International Health at Be ...
and Professor Morris J. Levy, who were both considered among "The Cardiology Founders of Israel" by doing the first cardiac puncture
catheterization In medicine, a catheter (/ˈkæθətər/) is a thin tube made from medical grade materials serving a broad range of functions. Catheters are medical devices that can be inserted in the body to treat diseases or perform a surgical procedure. Cath ...
, which was used on 80 patients in 1964. In 1958, Lillehei was responsible for the world's first use of a small, external, portable, battery-powered
pacemaker An artificial cardiac pacemaker (or artificial pacemaker, so as not to be confused with the natural cardiac pacemaker) or pacemaker is a medical device that generates electrical impulses delivered by electrodes to the chambers of the heart eith ...
. It was invented at his behest by
Earl Bakken Earl Elmer Bakken (January 10, 1924 – October 21, 2018) was an American engineer, businessman and philanthropist of Dutch and Norwegian American ancestry. He founded Medtronic, where he developed the first external, battery-operated, transi ...
, whose then-small company,
Medtronic Medtronic plc is an American medical device company. The company's operational and executive headquarters are in Minneapolis, Minnesota, and its legal headquarters are in Ireland due to its acquisition of Irish-based Covidien in 2015. While it ...
, designed and repaired electronics for the University of Minnesota hospital. After the introduction of the first widely used prosthetic heart valves by Albert Starr in 1961, Lillehei also developed and implanted several innovative designs: the Lillehei-Nakib toroidal disc (1966), the Lillehei-Kaster pivoting disc (1967), and the Kalke-Lillehei rigid bileaflet prosthesis (1968). As a dedicated educator, Lillehei trained more than 150 cardiac surgeons from 40 nations, including
Norman Shumway Norman Edward Shumway (February 9, 1923 – February 10, 2006) was a pioneer of heart surgery at Stanford University. He was the 67th president of the American Association for Thoracic Surgery and the first to perform an adult human to human ...
and Christiaan Barnard, who formed half of the quartet which pioneered heart transplantation (the others being Richard Lower and Adrian Kantrowitz). McRae, Donald (2007) ''Every Second Counts: The Race to Transplant the First Human Heart'' (Berkley Trade) In 1967, he was appointed
Lewis Atterbury Stimson Lewis Atterbury Stimson (August 24, 1844 – September 17, 1917 ) was an American surgeon who was the first to perform a public operation in the United States using Joseph Lister's antiseptic technique. Early life Stimson was born on August 24, ...
professor and chairman of the surgery department at
Cornell Medical Center The Joan & Sanford I. Weill Medical College of Cornell University is Cornell University's biomedical research unit and medical school located in Upper East Side, Manhattan, New York City, New York. Weill Cornell Medicine is affiliated with N ...
, New York. He returned to
St. Paul, Minnesota Saint Paul (abbreviated St. Paul) is the capital of the U.S. state of Minnesota and the county seat of Ramsey County. Situated on high bluffs overlooking a bend in the Mississippi River, Saint Paul is a regional business hub and the center o ...
, in 1975, where he became the director of medical affairs at
St. Jude Medical St. Jude Medical, Inc. was an American global medical device company headquartered in Little Canada, Minnesota, U.S., a suburb of Saint Paul. The company had more than 20 principal operations and manufacturing facilities worldwide with products s ...
. He was also named a clinical professor in the Department of Surgery at the
University of Minnesota The University of Minnesota, formally the University of Minnesota, Twin Cities, (UMN Twin Cities, the U of M, or Minnesota) is a public university, public Land-grant university, land-grant research university in the Minneapolis–Saint Paul, Tw ...
.


Honors

Lillehei's honors include the
Bronze Star The Bronze Star Medal (BSM) is a United States Armed Forces decoration awarded to members of the United States Armed Forces for either heroic achievement, heroic service, meritorious achievement, or meritorious service in a combat zone. Wh ...
for
World War II World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the vast majority of the world's countries—including all of the great powers—forming two opposin ...
service in
Italy Italy ( it, Italia ), officially the Italian Republic, ) or the Republic of Italy, is a country in Southern Europe. It is located in the middle of the Mediterranean Sea, and its territory largely coincides with the homonymous geographical re ...
, the 1955 Lasker Award, the
Order of Health Merit Jose Fernandez Madrid The Order of Health Merit Jose Fernandez Madrid ( es, Orden del Mérito Sanitario "José Fernández Madrid") is an Order (honour), order granted by Colombia, established in 1950. The order is awarded for distinguished service in the medical field t ...
by the government of
Colombia Colombia (, ; ), officially the Republic of Colombia, is a country in South America with insular regions in North America—near Nicaragua's Caribbean coast—as well as in the Pacific Ocean. The Colombian mainland is bordered by the Car ...
in 1959, the Golden Plate Award of the American Academy of Achievement in 1968, induction in 1993 into the Minnesota Inventors Hall of Fame, and the 1996 Harvey Prize in Science and Technology. In 1966-67, he served as president of the American College of Cardiology.


Personal life

In 1946, Dr. Lillehei was married to Katherine Ruth (Lindberg) Lillehei (1921-2012) with whom he had four children. Following his death in 1999, he was buried at the
Fort Snelling National Cemetery 3 Fort Snelling National Cemetery is a United States National Cemetery located in the Fort Snelling Unorganized Territory adjacent to the historic fort and Minneapolis–Saint Paul International Airport. It is the only National Cemetery in Minneso ...
. His youngest brother,
Richard C. Lillehei C. Lillehei (10 December 1927 - 1 April 1981) an American transplant surgeon best remembered for the world's first successful simultaneous pancreas-kidney transplant in 1966 (sometimes quoted as 1967) and the first known human intestinal transpl ...
, was a notable transplant surgeon in his own right, having participated in the world's first successful transplant of a pancreas in 1966 and the first known human transplant of the small and large intestines.History of Richard C. Lillehei
Lillehei Surgical Society.


References


Other sources


Borghi L. (2015) "Heart Matters. The Collaboration Between Surgeons and Engineers in the Rise of Cardiac Surgery". In: Pisano R. (eds) A Bridge between Conceptual Frameworks. History of Mechanism and Machine Science, vol 27. Springer, Dordrecht, pp. 53-68
*Cooper, David (2010)'' Open Heart: The Radical Surgeons who Revolutionized Medicine'' (Kaplan Publishing) *Goor, Daniel A. (2007) ''The Genius of C. Walton Lillehei and The True History of Open Heart Surgery'' (Vantage Press) * Miller, G. Wayne (2000) ''King of Hearts, The true story of the maverick who pioneered the open heart surgery'' (Times Books)


External links


The C. Walton and Richard C. Lillehei Surgical Society C. Walton Lillehei Resident Forum (American Association for Thoracic Surgery)C. Walton Lillehei Young Investigator's Award (European Association for Cardio-Thoracic Surgery)C. Walton Lillehei portraitC. Walton Lillehei in MNopedia, the Minnesota Encyclopedia1955 Albert LaskerClinical Medical Research Award for Advances in Cardiac Surgery
{{DEFAULTSORT:Lillehei, C. Walton American thoracic surgeons 1918 births 1999 deaths University of Minnesota Medical School alumni People from Minneapolis American people of Norwegian descent Physicians from Minnesota 20th-century surgeons