Melvin M. Grumbach
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Melvin Malcolm Grumbach (December 21, 1925 – October 4, 2016) was an American
pediatrician Pediatrics ( also spelled ''paediatrics'' or ''pædiatrics'') is the branch of medicine that involves the medical care of infants, children, adolescents, and young adults. In the United Kingdom, paediatrics covers many of their youth until the ...
and academic who specialized in pediatric endocrinology. Called Edward B. Shaw Distinguished Professor of Pediatrics, Emeritus at the
University of California, San Francisco The University of California, San Francisco (UCSF) is a public land-grant research university in San Francisco, California. It is part of the University of California system and is dedicated entirely to health science and life science. It cond ...
School of Medicine, Grumbach was noted for his research and writing on the effect of
hormones A hormone (from the Ancient Greek, Greek participle , "setting in motion") is a class of cell signaling, signaling molecules in multicellular organisms that are sent to distant organs by complex biological processes to regulate physiology and beh ...
and the
central nervous system The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain and spinal cord. The CNS is so named because the brain integrates the received information and coordinates and influences the activity of all par ...
on growth and puberty and their disorders; the function of the human sex chromosomes; and disorders of sexual development.


Career

After graduating from New Utrecht High School in
Brooklyn Brooklyn () is a borough of New York City, coextensive with Kings County, in the U.S. state of New York. Kings County is the most populous county in the State of New York, and the second-most densely populated county in the United States, be ...
, New York, and then attending Columbia College in New York City, Grumbach went on to earn his medical degree from the College of Physicians and Surgeons,
Columbia University Columbia University (also known as Columbia, and officially as Columbia University in the City of New York) is a private research university in New York City. Established in 1754 as King's College on the grounds of Trinity Church in Manhatt ...
, in 1948. He completed his internship at Mount Sinai Hospital in 1949 and his residency at Babies Hospital,
Columbia Presbyterian Medical Center The NewYork-Presbyterian Hospital is a nonprofit academic medical center in New York City affiliated with two Ivy League medical schools, Cornell University and Columbia University. The hospital comprises seven distinct campuses located in the New Y ...
in pediatrics under the direction of
Rustin McIntosh Rustin McIntosh (September 29, 1894 – February 14, 1986) was an American pediatrician. From 1930 until 1960, he was the chief of pediatrics at the Babies Hospital of NewYork–Presbyterian Hospital and the Reuben S. Carpentier Professor of Pediat ...
in 1951. During the
Korean War , date = {{Ubl, 25 June 1950 – 27 July 1953 (''de facto'')({{Age in years, months, weeks and days, month1=6, day1=25, year1=1950, month2=7, day2=27, year2=1953), 25 June 1950 – present (''de jure'')({{Age in years, months, weeks a ...
he served as a captain in the United States Air Force Medical Corps, with assignments at
Oak Ridge Institute of Nuclear Studies Oak Ridge Associated Universities (ORAU) is a consortium of American universities headquartered in Oak Ridge, Tennessee, with offices in Arlington, Virginia, Arvada, Colorado, Belcamp, Maryland, Cincinnati, Ohio and staff at other locations acros ...
in Tennessee and at
Fort Detrick Fort Detrick () is a United States Army Futures Command installation located in Frederick, Maryland. Historically, Fort Detrick was the center of the U.S. biological weapons program from 1943 to 1969. Since the discontinuation of that program, i ...
Biological Laboratories in Maryland. Following his military service, Grumbach did a fellowship with
Lawson Wilkins Lawson Wilkins (1894-1963) was a pioneering pediatric endocrinologist. He is known along with John Money for pioneering surgeries for visibly intersex newborns. Honors *Borden Award, American Academy of Pediatrics (1953) *Amory Prize, American Aca ...
at Johns Hopkins. He then returned to Babies Hospital and Columbia University in 1955, becoming founding director of the Pediatric Endocrine Division at Babies Hospital. In 1966 Grumbach was recruited to the University of California San Francisco as chairman of the Department of Pediatrics, and in 1983 he was named the first Edward B. Shaw Distinguished Professor of Pediatrics. Grumbach served as chairman of the Department of Pediatrics at University of California San Francisco for over two decades, transforming the department into one of the leading academic centers for pediatrics in the country. Grumbach stepped down as chairman of pediatrics in 1986 and retired in 1994, but he remained active in the field until December 2014.Miller, Walter L. (December 2016)
"In Memoriam: Melvin M. Grumbach (1925–2016)"
''
Endocrinology Endocrinology (from '' endocrine'' + '' -ology'') is a branch of biology and medicine dealing with the endocrine system, its diseases, and its specific secretions known as hormones. It is also concerned with the integration of developmental event ...
'', Vol. 157, Issue 12, pp. 4499–4501. Retrieved 6 October 2017.
Grumbach made many seminal contributions the understanding of pediatric endocrinology including extensive studies on the development and function of the endocrine and neuroendocrine systems from fetal life through puberty, as well as studies of the hormonal and genetic effects on growth, bone maturation, puberty, sex determination and differentiation (and their disorders) and disease-causing pathology. He was a past president of the
Endocrine Society The Endocrine Society is a professional, international medical organization in the field of endocrinology and metabolism, founded in 1916 as The Association for the Study of Internal Secretions. The official name of the organization was changed ...
, the American Pediatric Society, the Lawson Wilkins Pediatric Endocrine Society, the Association of Medical School Pediatric Department Chairmen, and honorary president of the International Endocrine Society. From 1956 to 1990 he supervised the training of 82 fellows from 15 countries on five continents. No single individual trained as many leaders or had a broader impact on pediatric endocrinology. He died on October 4, 2016, of a heart attack.Bai, Nina (7 October 2016)
"Melvin Malcolm Grumbach, Renowned Pediatric Endocrinologist, Dies at 90"
UCSF The University of California, San Francisco (UCSF) is a public land-grant research university in San Francisco, California. It is part of the University of California system and is dedicated entirely to health science and life science. It condu ...
News Center. Retrieved 6 October 2017.


Awards and honors

* 1966 Joseph Mather Smith Prize from
Columbia University Columbia University (also known as Columbia, and officially as Columbia University in the City of New York) is a private research university in New York City. Established in 1754 as King's College on the grounds of Trinity Church in Manhatt ...
* 1971 Collège de France Medal, Paris * 1971 Borden Award for Research in Pediatrics,
American Academy of Pediatrics The American Academy of Pediatrics (AAP) is an American professional association of pediatricians, headquartered in Itasca, Illinois. It maintains its Department of Federal Affairs office in Washington, D.C. Background The Academy was founded ...
* 1980 Robert H. Williams Distinguished Leadership Award, the
Endocrine Society The Endocrine Society is a professional, international medical organization in the field of endocrinology and metabolism, founded in 1916 as The Association for the Study of Internal Secretions. The official name of the organization was changed ...
* 1984 Elected Member,
Institute of Medicine The National Academy of Medicine (NAM), formerly called the Institute of Medicine (IoM) until 2015, is an American nonprofit, non-governmental organization. The National Academy of Medicine is a part of the National Academies of Sciences, E ...
of the
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...
* 1985 Fellow,
American Association for the Advancement of Science The American Association for the Advancement of Science (AAAS) is an American international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific respons ...
* 1988 Alumni Gold Medal for Distinguished Achievement in Medicine from
Columbia University Columbia University (also known as Columbia, and officially as Columbia University in the City of New York) is a private research university in New York City. Established in 1754 as King's College on the grounds of Trinity Church in Manhatt ...
College of Physicians and Surgeons * 1991 D.M. honoris causa,
University of Geneva The University of Geneva (French: ''Université de Genève'') is a public research university located in Geneva, Switzerland. It was founded in 1559 by John Calvin as a theological seminary. It remained focused on theology until the 17th centu ...
, Switzerland * 1992 Fred Conrad Koch Award and Medal for Research from the
Endocrine Society The Endocrine Society is a professional, international medical organization in the field of endocrinology and metabolism, founded in 1916 as The Association for the Study of Internal Secretions. The official name of the organization was changed ...
(shared with
Selna Kaplan Selna Lucille Kaplan (April 8, 1927 – July 21, 2010) was an American pediatric endocrinologist and a professor of pediatrics at the University of California, San Francisco. She led the first American clinical trials of growth hormone treatment. ...
) * 1995 Elected Member,
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...
* 1995 Elected Fellow,
American Academy of Arts and Sciences The American Academy of Arts and Sciences (abbreviation: AAA&S) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and ...
* 1996 Lifetime Achievement Medical Education Award from the
American Academy of Pediatrics The American Academy of Pediatrics (AAP) is an American professional association of pediatricians, headquartered in Itasca, Illinois. It maintains its Department of Federal Affairs office in Washington, D.C. Background The Academy was founded ...
* 1997
John Howland Award The John Howland Award is the highest honor bestowed by the American Pediatric Society (APS). Named in honor of John Howland (1873–1926), the award, with its accompanying medal, is presented annually by the American Pediatric Society for "dist ...
from the American Pediatric Society * 2000 D. honoris causa, University René Descartes, Paris V * 2006 Judson J. Van Wyk Prize for Career Achievement in Pediatric Endocrinology from the Lawson Wilkins Pediatric Endocrine Society * 2008 D. honoris causa, University of Athens, Greece * 2010 Recipient of the
University of California, San Francisco The University of California, San Francisco (UCSF) is a public land-grant research university in San Francisco, California. It is part of the University of California system and is dedicated entirely to health science and life science. It cond ...
Medal


References

{{DEFAULTSORT:Grumbach, Melvin M. 1925 births 2016 deaths University of California, San Francisco faculty American pediatric endocrinologists Physicians from New York City Military personnel from New York City Members of the United States National Academy of Sciences United States Air Force Medical Corps officers United States Air Force personnel of the Korean War Members of the National Academy of Medicine