Matthias Mann (born 10 October 1959) is a scientist in the area of

mass spectrometry Mass spectrometry (MS) is an analytical technique that is used to measure the mass-to-charge ratio of ions. The results are presented as a ''mass spectrum'', a plot of intensity as a function of the mass-to-charge ratio. Mass spectrometry is use ...

and

proteomics Proteomics is the large-scale study of proteins. Proteins are vital parts of living organisms, with many functions such as the formation of structural fibers of muscle tissue, enzymatic digestion of food, or synthesis and replication of DNA. In ...

Early life and education

Born in Germany he studied mathematics and physics at the

University of Göttingen The University of Göttingen, officially the Georg August University of Göttingen, (german: Georg-August-Universität Göttingen, known informally as Georgia Augusta) is a public research university in the city of Göttingen, Germany. Founded ...

. He received his Ph.D. in 1988 at

Yale University Yale University is a private research university in New Haven, Connecticut. Established in 1701 as the Collegiate School, it is the third-oldest institution of higher education in the United States and among the most prestigious in the wo ...

where he worked in the group of John Fenn, who was later awarded the

Nobel Prize in Chemistry ) , image = Nobel Prize.png , alt = A golden medallion with an embossed image of a bearded man facing left in profile. To the left of the man is the text "ALFR•" then "NOBEL", and on the right, the text (smaller) "NAT•" then "M ...

Career

After a postdoctoral fellowship at the University of Southern Denmark in

Odense Odense ( , , ) is the third largest city in Denmark (behind Copenhagen and Aarhus) and the largest city on the island of Funen. As of 1 January 2022, the city proper had a population of 180,863 while Odense Municipality had a population of 20 ...

Mann became group leader at the European Molecular Biology Laboratory (

EMBL The European Molecular Biology Laboratory (EMBL) is an intergovernmental organization dedicated to molecular biology research and is supported by 27 member states, two prospect states, and one associate member state. EMBL was created in 1974 and ...

) in Heidelberg. Later he went back to Odense as a professor of bioinformatics. Since 2005 he has been a director at the

Max Planck Institute of Biochemistry The Max Planck Institute of Biochemistry (MPIB) is a research institute of the Max Planck Society located in Martinsried, a suburb of Munich. The institute was founded in 1973 by the merger of three formerly independent institutes: the Max Planck ...

in Munich. In addition, he became a principal investigator at the newly founded "Novo Nordisk Foundation Center for Protein Research" in Copenhagen. From his research group in Munich originated in 2016 PreOmics – a company commercializing sample prep sets, and EVOSEP – a company commercializing protein analysis equipment.Prof. Matthias Mann joins PharmaFluidics’ Advisory Board
PharmaFluidics, press release of 22 October 2019 His work has impact in various fields of mass spectrometry-based proteomics: :* The peptide sequence tag approach developed at the EMBL was one of the first methods for the identification of peptides based on mass spectra and genome data. :* Nano-electrospray (an

electrospray The name electrospray is used for an apparatus that employs electricity to disperse a liquid or for the fine aerosol resulting from this process. High voltage is applied to a liquid supplied through an emitter (usually a glass or metallic capilla ...

technique with very low flow rates) was the first method that allowed femtomole sequencing of proteins from polyacrylamide gels. :* A recently developed metabolic labeling technique called

SILAC Stable Isotope Labeling by/with Amino acids in Cell culture (SILAC) is a technique based on mass spectrometry that detects differences in protein abundance among samples using non-radioactive isotopic labeling. It is a popular method for quantitativ ...

(stable isotope labeling with amino acids in cell culture) is widely used in

quantitative proteomics Quantitative proteomics is an analytical chemistry technique for determining the amount of proteins in a sample. The methods for protein identification are identical to those used in general (i.e. qualitative) proteomics, but include quantificatio ...

Other activities

* PharmaFluidics, Member of the Advisory Board (since 2019)

Awards and honors

*1991: Malcom Award by the journal Organic Mass Spectrometry *1996: Mattauch Herzog Prize in Mass Spectrometry *1997: Hewlett-Packard Prize for Strategic Research in Automation of Sample Preparation *1998: Edman Prize by the "Methods in Protein Structure Analysis" Society *1999: Bieman Medal for Outstanding Achievement in Mass Spectrometry (

American Society for Mass Spectrometry The American Society for Mass Spectrometry (ASMS) is a professional association based in the United States that supports the scientific field of mass spectrometry. As of 2018, the society had approximately 10,000 members primarily from the US, bu ...

) *1999: Named second most cited scientist in chemistry in the years 1994 to 1996 by the Institute of Scientific Information *1999: Elected visiting professor

Harvard Medical School Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consi ...

*1999: Elected to the

European Molecular Biology Organization The European Molecular Biology Organization (EMBO) is a professional, non-profit organization of more than 1,800 life scientists. Its goal is to promote research in life science and enable international exchange between scientists. It co-funds cour ...

(EMBO) *2000:

Meyenburg Prize The Meyenburg Prize is awarded for outstanding achievements in cancer research by the Meyenburg Foundation in support of the German Cancer Research Center, Heidelberg (DKFZ), which is the largest biomedical research institution in Germany. The pri ...

*2001: Bernhard and Matha Rasmussens Memorial award in Cancer Research *2001: Meyenburg Cancer Research Award given by the German Cancer Research Center *2001: Fresenius Prize and Medal for Analytical Chemistry given by the German Chemical Society *2004: Honorary Doctorate,

University of Utrecht Utrecht University (UU; nl, Universiteit Utrecht, formerly ''Rijksuniversiteit Utrecht'') is a public research university in Utrecht, Netherlands. Established , it is one of the oldest universities in the Netherlands. In 2018, it had an enrollme ...

, Netherlands *2004: Lundbeck Prize *2004: Novo-Nordisk Prize *2005: Anfinsen Award of the Protein Society *2006: "Biochemical Analysis" prize by the German Society for Clinical Chemistry and Laboratory Medicine *2008: HUPO Distinguished Achievement Award in Proteomic Science *2008: Bijvoet Medal of the

Bijvoet Center for Biomolecular Research The Bijvoet Centre for Biomolecular Research is a research institute at Utrecht University. The Bijvoet Centre performs research on the relation between the structure and function of biomolecules, including proteins and lipids, which play a role ...

Utrecht University Utrecht University (UU; nl, Universiteit Utrecht, formerly ''Rijksuniversiteit Utrecht'') is a public research university in Utrecht, Netherlands. Established , it is one of the oldest universities in the Netherlands. In 2018, it had an enrollme ...

*2010: Friedrich Wilhelm Joseph von Schelling-Prize by the Bavarian Academy of Sciences and Humanities *2012:

Gottfried Wilhelm Leibniz Gottfried Wilhelm (von) Leibniz . ( – 14 November 1716) was a German polymath active as a mathematician, philosopher, scientist and diplomat. He is one of the most prominent figures in both the history of philosophy and the history of mathema ...

Prize by

German Research Foundation The German Research Foundation (german: Deutsche Forschungsgemeinschaft ; DFG ) is a German research funding organization, which functions as a self-governing institution for the promotion of science and research in the Federal Republic of Germ ...

*2012: Feodor Lynen Medal *2012:

Louis-Jeantet Prize for Medicine Established in 1986, the Louis-Jeantet Prizes are funded by the ''Fondation Louis-Jeantet'' and awarded each year to experienced researchers who have distinguished themselves in the field of biomedical research in one of the member states of t ...

*2012:

Ernst Schering Prize The Ernst Schering Prize is awarded annually by the Ernst Schering Foundation for especially outstanding basic research in the fields of medicine, biology or chemistry anywhere in the world. Established in 1991 by the Ernst Schering Research Found ...

* 2015: Theodor Bücher Lecture and Medal * 2015: Danish Order of Dannebrog Knights Cross * 2015: Barry L. Karger Medal in Bioanalytical Chemistry * 2017: Lennart Philipson Award

References

External links

*
Homepage of the Mann department at the MPI of Biochemistry
* Nature article about the Novo Nordisk Foundation Center for Protein Researc

{{DEFAULTSORT:Mann, Matthias German biochemists Living people 20th-century German biologists 1959 births Bijvoet Medal recipients Gottfried Wilhelm Leibniz Prize winners Mass spectrometrists 21st-century German biologists Max Planck Society people Members of the German Academy of Sciences Leopoldina Members of the Bavarian Academy of Sciences Members of the European Molecular Biology Organization Max Planck Institute directors