Matthew Rabinowitz
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Matthew Rabinowitz (born 4 February 1973) is a South African entrepreneur and investor. He is the co-founder and executive chairman of
Natera Natera, Inc. is a clinical genetic testing company based in Austin, Texas that specializes in non-invasive, cell-free DNA (cfDNA) testing technology, with a focus on women’s health, cancer, and organ health. Natera’s proprietary technology ...
(NTRA), a clinical genetic testing company. He serves as executive chairman, board member, adviser and angel investor to several companies and non-profits in diagnostics, biotech, gene editing, preventative healthcare, machine learning and conservation. Rabinowitz has been a consulting professor in Aeronautics and Astronautics at Stanford University, Visiting Faculty in Genetics at Harvard Medical School, and his technologies have generated over 100 patents and peer-reviewed publications, including the genetics, reproductive and oncology journals, ''
Science Science is a systematic endeavor that builds and organizes knowledge in the form of testable explanations and predictions about the universe. Science may be as old as the human species, and some of the earliest archeological evidence for ...
'' and the cover of ''
Nature Nature, in the broadest sense, is the physics, physical world or universe. "Nature" can refer to the phenomenon, phenomena of the physical world, and also to life in general. The study of nature is a large, if not the only, part of science. ...
''. In 2006, he received the Scott Helt Memorial award from IEEE for his work in wireless communication and navigation.


Early life and education

Matthew Rabinowitz was born on 4 February 1973 in Johannesburg, South Africa. His parents, Bernard “Bokkie” Rabinowitz and Ruth Rabinowitz (née Zilibowitz) were both doctors. From 1955 to 1985, Bokkie Rabinowitz was a general surgeon in South Africa after which he continued surgical teaching until 1996. Ruth was an MD who also qualified as a homeopath. As the South African Apartheid state was coming to an end, Ruth entered political activism. She was a Member of Parliament (MP) and Senator in South Africa, representing the
Inkatha Freedom Party The Inkatha Freedom Party ( zu, IQembu leNkatha yeNkululeko, IFP) is a right-wing political party in South Africa. The party has been led by Velenkosini Hlabisa since the party's 2019 National General Conference. Mangosuthu Buthelezi founded t ...
for 15 years as Health Spokesperson. Rabinowitz attended Sandown Primary School and
Redhill School (Johannesburg) Redhill School is a private English medium co-educational multi-faith day school located in Morningside, Johannesburg, Gauteng, South Africa. The school's motto is 'Free to Build'.Redhill School website http://www.redhill.co.za/ It was foun ...
in South Africa where he won the South African National Science Olympiad in 1990. In 1991, he attended the
University of the Witwatersrand The University of the Witwatersrand, Johannesburg (), is a multi-campus South African Public university, public research university situated in the northern areas of central Johannesburg. It is more commonly known as Wits University or Wits ( o ...
where he studied astronomy, maths, philosophy, accounting and electrical engineering. In 1996, he relocated to the US after receiving a scholarship to attend Stanford University where he completed a Bachelor of Arts, Humanities and Social Sciences. In 2000, Rabinowitz completed a Ph.D. in Electrical Engineering with a minor in Aeronautics and Astronautics. He received the Levine Award and Terman Award for outstanding research and academics in the Departments of Physics and the School of Engineering. He was granted a graduate fellowship to the Stanford School of Engineering, and went on to complete a Ph.D. in Electrical Engineering.


Career

In 1998, Rabinowitz co-founded Panopticon, an intelligent online merchandising company which sold for $100 million in 2000. In 2000, he founded the Rosum Corporation with the creators of
GPS The Global Positioning System (GPS), originally Navstar GPS, is a Radionavigation-satellite service, satellite-based radionavigation system owned by the United States government and operated by the United States Space Force. It is one of t ...
. Under Rabinowitz’ leadership as CEO (and CTO a few years later), Rosum developed a location technology using digital TV signals to augment GPS for positioning indoors and urban areas where GPS signal is inactive. The company was ultimately not a financial success as high bandwidth cellular replaced digital TV in mobile devices. Following advances in the
Human Genome Project The Human Genome Project (HGP) was an international scientific research project with the goal of determining the base pairs that make up human DNA, and of identifying, mapping and sequencing all of the genes of the human genome from both a ...
, in 2005, Rabinowitz founded
Natera Natera, Inc. is a clinical genetic testing company based in Austin, Texas that specializes in non-invasive, cell-free DNA (cfDNA) testing technology, with a focus on women’s health, cancer, and organ health. Natera’s proprietary technology ...
to deliver a range of prenatal, oncology and organ transplant tests, and genetic counselling services to address genetic diseases. Natera’s flagship noninvasive prenatal test, Panorama, has generated roughly 50 peer-reviewed publications and has changed the management of pregnancy while reducing the use of invasive tests like amniocentesis. Rabinowitz is the co-founder and chairman of MyOme, a health technology company founded in 2017 that aims to reduce medical costs and improve health outcomes using whole genome sequencing (WGS) and polygenic predictive modelling. MyOme is developing a range of WGS-related diagnostics and interventions, such as
in-vitro fertilization In vitro fertilisation (IVF) is a process of fertilisation where an egg is combined with sperm in vitro ("in glass"). The process involves monitoring and stimulating an individual's ovulatory process, removing an ovum or ova (egg or eggs) ...
cycles using full genome reconstruction to evaluate 30 polygenic disease models for cancer, autoimmune, cardiovascular, metabolic, and cognitive conditions. MyOme has also created a clinical risk prediction for breast cancer and other phenotypes. The company's investors include
Sequoia Capital Sequoia Capital is an American venture capital firm. The firm is headquartered in Menlo Park, California, and specializes in seed stage, early stage, and growth stage investments in private companies across technology sectors. , Sequoia's total a ...
. Rabinowitz is the founder and executive chairman of NatureEye, a drone technology start-up that provides alternative profit models and anti-poaching tools for wildlife conservancies. Rabinowitz set up Marble Therapeutics out of the Wyss Institute at Harvard Medical School in 2022 and serves as executive chairman. The company develops anti-aging therapeutics that leverage gene therapies to modulate gene signalling pathways. Its technology uses
chaos theory Chaos theory is an interdisciplinary area of scientific study and branch of mathematics focused on underlying patterns and deterministic laws of dynamical systems that are highly sensitive to initial conditions, and were once thought to have co ...
and nonlinear dynamical modelling of longitudinal genetic data.


Personal life

In 2003, Rabinowitz’s sister gave birth to a baby with Down Syndrome who died soon after. Rabinowitz said the experience motivated him to establish a start-up that offered advanced informatics and clinical genetic testing, such as screening tests for women as an alternative to invasive amniocentesis to learn of inherited or genetic disorders early in pregnancy.


References

{{DEFAULTSORT:Rabinowitz, Matthew Living people 1973 births South African businesspeople