Mathias Uhlén (born May 1954) is a Swedish biologist,

biotechnologist Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used b ...

, and Professor of Microbiology at Royal Institute of Technology (KTH), Stockholm. His research interests cover antibody engineering,

proteomics Proteomics is the large-scale study of proteins. Proteins are vital parts of living organisms, with many functions such as the formation of structural fibers of muscle tissue, enzymatic digestion of food, or synthesis and replication of DNA. In ...

and

precision medicine Precision, precise or precisely may refer to: Science, and technology, and mathematics Mathematics and computing (general) * Accuracy and precision, measurement deviation from true value and its scatter * Significant figures, the number of digit ...

Life

In 1984 Uhlén received his PhD at the Royal Institute of Technology (KTH) in Stockholm. After being employed at the

European Molecular Biology Laboratory The European Molecular Biology Laboratory (EMBL) is an intergovernmental organization dedicated to molecular biology research and is supported by 27 member states, two prospect states, and one associate member state. EMBL was created in 1974 and ...

Heidelberg Heidelberg (; Palatine German language, Palatine German: ''Heidlberg'') is a city in the States of Germany, German state of Baden-Württemberg, situated on the river Neckar in south-west Germany. As of the 2016 census, its population was 159,914 ...

, Germany, he became professor at KTH in 1988. His research has led to more than 750 publications, 80,000 citations. In 2003, as part of an international project to map the complete human proteome and transcriptome system, the

Human Protein Atlas The Human Protein Atlas (HPA) is a Swedish-based program started in 2003 with the aim to map all the human proteins in cells, tissues and organs using integration of various omics technologies, including antibody-based imaging, mass spectrometr ...

project was created and launched. Uhlén is Program Director of the project. There are six additional projects within the primary project. * The Tissue Atlas is a Swedish project to provide expression profiles of human genes both on the mRNA and protein level, within the body. * The Cell Atlas provides high-resolution insights into the spatial distribution of proteins within cells. * The Pathology Atlas showing how cancer patient survival is tied to RNA and protein levels. The project contains

mRNA In molecular biology, messenger ribonucleic acid (mRNA) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene, and is read by a ribosome in the process of Protein biosynthesis, synthesizing a protein. mRNA is ...

and protein expression data for the most common forms of human cancer. * The Blood Atlas showing the expression of proteins in human immune cells and also mapping the proteins in human blood * The Brain Atlas showing the proteins expressed in the different parts of human, pig and mouse brains. * The Single Cell Type Atlas shows single cell RNA sequencing (scRNAseq) data from 13 different human tissues, together with immunohistochemically stained tissue sections visualizing the corresponding spatial protein expression patterns.

Awards and honours

He is member of the * National Academy of Engineering (NAE) in USA, the Royal Swedish Academy of Science (KVA). * Royal Academy of Engineering Sciences (IVA) * European Molecular Biology Organization (EMBO). He is the President of the

European Federation of Biotechnology The European Federation of Biotechnology (EFB) was established by European scientists in 1978. It is a non-profit federation of national biotechnology associations, learned societies, universities, scientific institutes, biotechnology companies ...

. From 2010 to 2015, he was the founding Director of the Science for Life Laboratory (SciLifeLab) which is a national center for molecular bioscience.

References

External links

* {{DEFAULTSORT:Uhlen, Mathias 1954 births Living people Swedish microbiologists KTH Royal Institute of Technology alumni Academic staff of the KTH Royal Institute of Technology