Mediator of RNA polymerase II transcription subunit 21 is an
enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
that in humans is encoded by the ''MED21''
gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
.
Interactions
MED21 has been shown to
interact
Advocates for Informed Choice, dba interACT or interACT Advocates for Intersex Youth, is a 501(c)(3) nonprofit organization using innovative strategies to advocate for the legal and human rights of children with intersex traits. The organizati ...
with:
*
BRCA1
Breast cancer type 1 susceptibility protein is a protein that in humans is encoded by the ''BRCA1'' () gene. Orthologs are common in other vertebrate species, whereas invertebrate genomes may encode a more distantly related gene. ''BRCA1'' is a h ...
,
*
CDK8
Cell division protein kinase 8 is an enzyme that in humans is encoded by the ''CDK8'' gene.
Function
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK8 and cyclin C associate with the mediato ...
,
*
GTF2F1
General transcription factor IIF subunit 1 is a protein that in humans is encoded by the ''GTF2F1'' gene.
Interactions
GTF2F1 has been shown to interact with:
* CTDP1,
* GTF2H4,
* HNRPU,
* MED21,
* POLR2A,
* Serum response factor
* TAF1 ...
,
[
* ]GTF2H4
General transcription factor IIH subunit 4 is a protein that in humans is encoded by the ''GTF2H4'' gene.
Interactions
GTF2H4 has been shown to interact with:
* GTF2F1,
* MED21,
* POLR2A,
* TATA binding protein,
* Transcription Factor II B ...
,[
* ]MED6
Mediator of RNA polymerase II transcription subunit 6 is one of the subunits of the Mediator complex. It is an enzyme that in humans is encoded by the ''MED6'' gene.
Protein family
This family of proteins represent the transcriptional mediat ...
, and
* POLR2A
DNA-directed RNA polymerase II subunit RPB1, also known as RPB1, is an enzyme that in humans is encoded by the ''POLR2A'' gene.
Function
This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing me ...
.[
]
References
Further reading
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
{{Gene-12-stub