Cyclic GMP-AMP synthase is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
that in humans is encoded by the CGAS
gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
.
[
]
It's an
enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
, a
nucleotidyltransferase, a
cyclic GMP-AMP synthase
Cyclic GMP-AMP synthase (cGAS, Cyclic guanosine monophosphate–adenosine monophosphate, cGAMP synthase), belonging to the nucleotidyltransferase family, is a The cGAS – STING cytosolic DNA sensing pathway, cytosolic DNA sensor that activates a ...
.
References
Further reading
External links
PDBe-KBprovides an overview of all the structure information available in the PDB for Human Cyclic GMP-AMP synthase (MB21D1)
{{gene-6-stub
Human proteins