List of people from Pennsylvania

Pennsylvania, the fifth most populous state in the United States, is the birthplace or childhood home of many famous Americans. People from Pennsylvania are called "Pennsylvanians".

The following is a list of notable Americans who were born and/or lived a significant portion of their lives in Pennsylvania along with their primary Pennsylvania city or town of residence:

Actors

; A–B

* Erika Alexander— Philadelphia
* Keith Andes—Philadelphia
* Gerald Anthony— Pittsburgh
* Aquaria— West Chester
* Carmen Argenziano—Sharon
* Malcolm Atterbury—Philadelphia
* Frankie Avalon—Philadelphia
* Val Avery—Philadelphia
* Jack Avery (singer)— Susquehanna
* Kevin Bacon —Philadelphia
* Brian Baker—Philadelphia
* Carroll Baker— Johnstown
* Sue Ball—Philadelphia
* Mabel Ballin—Philadelphia
* George Bancroft—Philadelphia
* George Barbier—Philadelphia
* Vince Barnett—Pittsburgh
* Eddie Barry—Philadelphia
* Ethel Barrymore—Philadelphia
* John Barrymore—Philadelphia
* Lionel Barrymore—Philadelphia
* Eddie Barth—Philadelphia
* Jessica Barth—Philadelphia
* Billy Barty— Millsboro
* Blake Bashoff—Philadelphia
* Toni Basil—Philadelphia
* Victory Bateman—Philadelphia
* Henry Bean—Philadelphia
* Billy Beck—Philadelphia
* Laurie Beechman—Philadelphia
* Chris Beetem—Philadelphia
* Beth Behrs— Lancaster
* Willam Belli—Philadelphia
* Maria Bello— Norristown
* Julie Benz— Murrysville
* Jeff Bergman—Philadelphia
* Ed Bernard—Philadelphia
* Lyle Bettger—Philadelphia
* Marki Bey—Philadelphia
* Edward Binns—Philadelphia
* Joey Bishop—Philadelphia
* Larry Bishop—Philadelphia
* Janet Blair— Altoona
* Billy Blanks— Erie
* Marc Blucas—Butler
* Eleanor Boardman—Philadelphia
* Walter Bobbie— Scranton
* Rudy Bond—Philadelphia
* David Boreanaz—Philadelphia
* Elizabeth Crocker Bowers—Philadelphia
* Christian Bowman— Harrisburg
* Jim Boyd—Philadelphia
* Peter Boyle—Philadelphia
* Glenn Branca—Harrisburg
* Laura Breckenridge— Flourtown
* El Brendel—Philadelphia
* David Brenner—Philadelphia
* Al Bridge—Philadelphia
* Fran Brill—Chester
* Charles Bronson— Ehrenfeld
* Scott Martin Brooks—Philadelphia
* Robert Curtis Brown— Bucks County
* Andrew Bryniarski—Philadelphia
* Bobby Burns—Philadelphia
* Edmund Burns—Philadelphia
* Steve Burns— Boyertown/ Gilbertsville
* Fritzi Burr—Philadelphia
* Clarissa Burt—Philadelphia
* Eugene Byrd—Philadelphia

; C–D

* Rachel Carson— Springdale
* Sabrina Carpenter— East Greenville
* Alexandra Chando— Bethlehem
* Kitty Chen—Philadelphia
* Dennis Christopher—Philadelphia
* Brian Patrick Clarke— Gettysburg
* Caitlin Clarke— Pittsburgh
* Lauren Cohan—Philadelphia
* Julia Cohen (born 1989)—Philadelphia
* Jack Coleman— Easton
* Marc Connelly— McKeesport
* Michael Constantine— Reading
* Josh Cooke—Philadelphia
* Bradley Cooper—Jenkintown
* Ellen Corby—Philadelphia
* Bill Cosby—Philadelphia
* Michael Cornacchia—Philadelphia
* Dolores Costello—Pittsburgh
* Maurice Costello—Pittsburgh
* Erin Cottrell—Yardley, Pennsylvania, Yardley
* Broderick Crawford—Philadelphia
* Rebecca Creskoff—Philadelphia
* Pat Crowley—Olyphant, Pennsylvania, Olyphant
* Jon Daly (comedian), Jon Daly—Pittsburgh
* James Darren—Philadelphia
* John Davidson (entertainer), John Davidson—Pittsburgh
* Ann B. Davis— Erie
* Bruce Davison—Philadelphia
* John de Lancie—Philadelphia
* Kim Delaney—Roxborough, Pennsylvania, Roxborough
* Kat Dennings—Bryn Mawr, Pennsylvania, Bryn Mawr
* Joe DeRosa (comedian), Joe DeRosa—Collegeville, Pennsylvania, Collegeville
* Patti Deutsch—Pittsburgh
* Devon (actress), Devon—Hellertown, Pennsylvania, Hellertown
* Mia Dillon—Newtown Township, Delaware County, Pennsylvania#Education, Newtown Township
* Joanie Dodds—Beaver Falls, Pennsylvania, Beaver Falls
* Jack Dodson—Pittsburgh
* John Doman—Philadelphia
* Heather Donahue—Upper Darby, Pennsylvania, Upper Darby
* Omar Doom— Easton
* Ellen Albertini Dow—Mount Carmel, Pennsylvania, Mount Carmel
* Ralph Dunn—Titusville, Pennsylvania, Titusville

; E–G

* Lisa Eichhorn— Reading
* Lisa Emery—Pittsburgh
* Chip Esten—Pittsburgh
* Patrick Fabian—Pittsburgh / New Cumberland, Pennsylvania, New Cumberland
* Tina Fey—Upper Darby, Pennsylvania, Upper Darby
* W.C. Fields—Philadelphia
* Larry Fine—Philadelphia
* Bette Ford— McKeesport
* Meg Foster— Reading
* Matthew Fox (actor), Matthew Fox—Abington Township, Montgomery County, Pennsylvania, Abington
* Jonathan Frakes—Bellefonte, Pennsylvania, Bellefonte
* Martin Gabel—Philadelphia
* Megan Gallagher— Reading
* Kyle Gallner— West Chester
* Rita Gam—Pittsburgh
* Billy Gardell—Pittsburgh
* Janet Gaynor—Philadelphia
* Deborah Geffner—Pittsburgh
* Richard Gere—Philadelphia
* Ileen Getz—Bristol, Pennsylvania, Bristol
* Todd Glass—Philadelphia
* Scott Glenn—Pittsburgh
* Jeff Goldblum—Pittsburgh
* Eve Gordon—Pittsburgh
* Frank Gorshin—Pittsburgh
* Seth Green—Philadelphia
* Charles Grodin—Pittsburgh
* Jonathan Groff— Lancaster

; H–K

* Kevin Peter Hall—Pittsburgh
* Charles Hallahan—Philadelphia
* Veronica Hamel—Philadelphia
* Kevin Hart (actor), Kevin Hart—Philadelphia
* Tim Heidecker—Allentown, Pennsylvania, Allentown
* Sherman Hemsley—Philadelphia
* Lauren Holly—Bristol, Pennsylvania, Bristol
* Gillian Jacobs—Mt. Lebanon, Pennsylvania, Mt. Lebanon
* Anthony Jeselnik—Pittsburgh / Upper St. Clair Township, Allegheny County, Pennsylvania, Upper St. Clair
* Cherie Johnson—Pittsburgh
* Clark Johnson—Philadelphia
* Russell Johnson—Ashley, Pennsylvania, Ashley
* Johnny Jolin—Montoursville, Pennsylvania, Montoursville
* Angela Jones—Greensburg, Pennsylvania, Greensburg
* Shirley Jones—Charleroi, Pennsylvania, Charleroi
* Mario Joyner—Pittsburgh
* James Karen—Wilkes-Barre, Pennsylvania, Wilkes-Barre
* JP Karliak– Scranton
* Tim Kazurinsky— Johnstown
* Staci Keanan–Devon, Pennsylvania, Devon
* Michael Keaton—Pittsburgh
* Sheila Kelley (American actress), Sheila Kelley—Greensburg, Pennsylvania, Greensburg
* Gene Kelly—Pittsburgh
* Grace Kelly (Princess of Monaco)—Philadelphia
* Michael Kelly (American actor), Michael Kelly—Philadelphia
* Jamie Kennedy—Upper Darby, Pennsylvania, Upper Darby
* Rya Kihlstedt—Lancaster
* Daniel Dae Kim— Bethlehem
* Taylor Kinney—Lancaster
* Jack Klugman—Philadelphia
* Eddie Korbich—Shamokin, Pennsylvania, Shamokin
* Harley Jane Kozak—Wilkes-Barre, Pennsylvania, Wilkes-Barre
* Nancy Kulp—Mifflintown, Pennsylvania, Miffilintown
* Jack Krizmanich—Phoenixville, Pennsylvania, Phoenixville

; L–M

* Liz Larsen—Philadelphia
* Andrew Lawrence (actor), Andrew Lawrence—Philadelphia
* Joey Lawrence—Philadelphia
* Matthew Lawrence—Abington Township, Montgomery County, Pennsylvania, Abington Township
* Joshua Leonard—State College, Pennsylvania, State College
* Richard LeParmentier—Pittsburgh
* David Lewis (American actor), David Lewis—Philadelphia
* Gilbert Lewis (actor), Gilbert Lewis—Philadelphia
* Heather Lind—Upland, Pennsylvania, Upland
* Jonathan Loughran—Philadelphia
* Beverly Lynne—Sellersville, Pennsylvania, Sellersville
* Jeanette MacDonald—Philadelphia
* Aline MacMahon—Pittsburgh
* Connor Maloney—Harrisburg
* Joe Manganiello—Pittsburgh / Mt. Lebanon, Pennsylvania, Mt. Lebanon
* Jayne Mansfield—Bryn Mawr, Pennsylvania, Bryn Mawr
* Bam Margera— West Chester
* Mark Margolis—Philadelphia
* Hugh Marlowe—Philadelphia
* Adoni Maropis—Pittsburgh
* Joe Maross—Barnesboro, Pennsylvania, Barnesboro
* Lynne Marta—Philadelphia
* Al Martino—Philadelphia
* Eric Martsolf—Harrisburg
* Jackie Mason—Latrobe, Pennsylvania, Latrobe
* Mark Matkevich—Philadelphia
* Elaine May—Philadelphia
* Melanie Mayron—Philadelphia
* Mitzi McCall—Pittsburgh
* Brooke McCarter—Philadelphia
* Paul McCrane—Philadelphia / Richboro, Pennsylvania, Richboro
* Mary McDonnell—Wilkes-Barre, Pennsylvania, Wilkes-Barre
* Rob McElhenney—Philadelphia
* Matthew McGrory—West Chester University, West Chester
* Joel McHale—Philadelphia
* Frank McHugh—Allegheny County
* Kate McNeil—Philadelphia
* Larry Mendte—Lansdowne, Pennsylvania, Lansdowne
* Adolphe Menjou—Pittsburgh
* Charles Meredith (actor), Charles Meredith—Knoxville, Pennsylvania, Knoxville
* Mary Lou Metzger—Philadelphia
* James A Michener—Doylestown, Pennsylvania, Doylestown
* Kate Micucci—Nazareth, Pennsylvania, Nazareth
* Vic Mignogna—Pittsburgh
* R. A. Mihailoff—Titusville, Pennsylvania, Titusville
* Dennis Miller—Pittsburgh
* Jason Miller (playwright), Jason Miller— Scranton
* Lara Jill Miller—Allentown
* Kristin Minter—Yardley, Pennsylvania, Yardley
* Cameron Mitchell (actor), Cameron Mitchell—Dallastown, Pennsylvania, Dallastown
* Tom Mix—Mix Run, Pennsylvania, Mix Run
* Katherine Moennig—Philadelphia
* Kelly Monaco—Philadelphia
* Pauline Moore—Harrisburg
* Jillian Murray— Reading

; N–R

* Kelly Neal—Philadelphia
* Irene Ng (actress), Irene Ng—Allentown
* Greg Nicotero—Pittsburgh
* J. J. North—Philadelphia
* Jay Oakerson—Philadelphia
* Cheri Oteri—Upper Darby
* Jerry Orbach—Wilkes-Barre, Pennsylvania, Wilkes-Barre
* Beth Ostrosky—Pittsburgh
* Jack Palance—Hazle Township, Pennsylvania, Hazle Township
* Stuart Pankin—Philadelphia
* Sydney Park (entertainer), Sydney Park—Philadelphia
* Adrian Pasdar—Powelton Village, Philadelphia, Pennsylvania, Powelton Village
* Steven Pasquale—Hershey, Pennsylvania, Hershey
* Michele Pawk—Butler
* Pamela Payton-Wright—Pittsburgh
* Kelly Perine—State College, Pennsylvania, State College
* Robert Picardo—Philadelphia
* Pink (singer), Pink (Alecia Moore)—Doylestown
* Joel Polis—Philadelphia
* Jon Polito—Philadelphia
* Billy Porter (entertainer), Billy Porter—Pittsburgh
* William Powell—Pittsburgh
* Robert Prosky—Philadelphia
* Zachary Quinto—Pittsburgh
* James Rebhorn—Philadelphia
* Krysten Ritter—Bloomsburg, Pennsylvania, Bloomsburg/Shickshinny, Pennsylvania, Shickshinny
* Erica Rivera—Philadelphia
* Keith Robinson (comedian), Keith Robinson—Philadelphia
* Holly Robinson Peete, Holly Robinson-Peete—Philadelphia
* Daniel Roebuck— Bethlehem
* Fred Rogers—Latrobe
* George A. Romero—Pittsburgh
* Norman Rose—Philadelphia
* Zelda Rubinstein—Pittsburgh
* Herbert Rudley—Philadelphia

; S–Z

* Bob Saget—Philadelphia
* Diane Salinger—Philadelphia
* Richard Sanders (actor), Richard Sanders—Harrisburg
* Tom Savini—Pittsburgh
* Jennifer Sciole—Philadelphia
* Lizabeth Scott—Scranton
* David O. Selznick—Pittsburgh
* Amanda Seyfried—Allentown
* Craig Sheffer—York, Pennsylvania, York
* M. Night Shyamalan—Philadelphia
* Penny Singleton—Philadelphia
* Emil Sitka— Johnstown
* Jonathan Slavin—Wilkes-Barre, Pennsylvania, Wilkes-Barre
* Kerr Smith—Exton, Pennsylvania, Exton
* Will Smith—Philadelphia
* Dana Snyder—Allentown
* Timothy Stack—Doylestown
* Robert Sterling—New Castle, Pennsylvania, New Castle
* James Stewart—Indiana, Pennsylvania, Indiana
* Sharon Stone—Saegertown, Pennsylvania, Meadville area
* Joseph Sweeney (actor), Joseph Sweeney—Philadelphia
* Taylor Swift—West Reading, Pennsylvania, West Reading
* Christine Taylor—Allentown
* Holland Taylor—Philadelphia
* Teller (magician), Teller—Philadelphia
* Miles Teller—Downingtown, Pennsylvania, Downingtown
* Mary Testa—Philadelphia
* Jonathan Taylor Thomas—Bethlehem
* Paul F. Tompkins—Philadelphia
* William Tracy—Pittsburgh
* Tom Verica—Philadelphia
* Mike Vogel—Abington Township, Montgomery County, Pennsylvania, Abington/Warminster Township, Bucks County, Pennsylvania, Warminster
* Brendon Walsh—Philadelphia
* Lisa Waltz—Limerick Township, Montgomery County, Pennsylvania, Limerick
* Eric Wareheim—Audubon, Pennsylvania, Audubon
* Fritz Weaver—Pittsburgh
* Michael Willis—Lancaster
* Thomas F. Wilson—Philadelphia/Wayne, Pennsylvania, Wayne
* Danny Woodburn—Philadelphia
* Chris Young (actor), Chris Young—Chambersburg, Pennsylvania, Chambersburg
* Winter Ave Zoli—New Hope, Pennsylvania, New Hope

Artists

* Julian Abele, architect— Philadelphia
* Alice Aycock, sculptor— Harrisburg
* Edmund Bacon (architect), Edmund Bacon, architect—Philadelphia
* Paul Bartholomew, architect—Ligonier, Pennsylvania, Ligonier
* Karen Bausman, architect—Allentown, Pennsylvania, Allentown
* Alison Bechdel, graphic novelist—Beech Creek, Pennsylvania, Beech Creek
* Cecilia Beaux, painter—Philadelphia
* Alexander Calder, sculptor—Lawnton, Pennsylvania, Lawnton
* Mary Cassatt, painter—Allegheny, Pennsylvania, Allegheny City
* George Catlin, painter—Wilkes-Barre, Pennsylvania, Wilkes-Barre
* Stuart Davis (painter), Stuart Davis, painter—Philadelphia
* Charles Demuth, painter— Lancaster
* Steve Ditko, comic book artist— Johnstown
* Thomas Eakins, painter—Philadelphia
* William Glackens, painter—Philadelphia
* Martha Graham, modern dancer and choreographer—Allegheny, Pennsylvania, Allegheny City
* Keith Haring, painter—Kutztown, Pennsylvania, Kutztown
* Jerry Harris (artist), Jerry Harris, sculptor— Pittsburgh
* William Stanley Haseltine, painter—Philadelphia
* Mike Hawthorne, comic book artist, illustrator—York, Pennsylvania, York
* Martin Johnson Heade, painter—Lumberville, Pennsylvania, Lumberville
* Gelsey Kirkland, ballerina— Bethlehem
* Franz Kline, painter—Wilkes-Barre, Pennsylvania, Wilkes-Barre
* Jeff Koons, sculptor—York
* Nate Lewis (artist), Nate Lewis, visual artist—Beaver Falls, Pennsylvania, Beaver Falls
* Thaddeus Mosley, sculptor—Pittsburgh
* Alice Neel, painter—Colwyn, Pennsylvania, Colwyn
* Violet Oakley, painter—Philadelphia
* Maxfield Parrish, illustrator—Philadelphia
* Philip Pearlstein, painter—Pittsburgh
* Joseph Pennell, illustrator—Philadelphia
* Man Ray, artist and photographer—Philadelphia
* Charles Sheeler, painter, photographer—Philadelphia
* Grover Simcox, illustrator—Philadelphia
* John French Sloan, John Sloan, painter—Lock Haven, Pennsylvania, Lock Haven
* Gary Mark Smith, global street photographer—Kutztown, Pennsylvania, Kutztown
* Jeff Smith (cartoonist), Jeff Smith, cartoonist—McKees Rocks, Pennsylvania, McKees Rocks
* Thomas Ustick Walter, architect—Philadelphia
* Andy Warhol, pop culture artist—Pittsburgh
* Neil Welliver, landscape artist—Millville
* Andrew Wyeth, painter—Chadds Ford Township, Pennsylvania, Chadds Ford Township
* Jamie Wyeth, painter (son of Andrew)—Chadds Ford Township
* N.C. Wyeth, illustrator (father of Andrew)—Chadds Ford Township
* Bunny Yeager, photographer—Wilkinsburg, Pennsylvania, Wilkinsburg

Astronauts

* Jerome Apt, NASA astronaut— Pittsburgh
* Guion S. Bluford, astronaut, first African-American man in space— Philadelphia
* Pete Conrad, Project Gemini, Gemini, Apollo 12, Apollo, and Skylab 2, Skylab astronaut, third man to walk on the Moon—Philadelphia
* Michael Fincke—Pittsburgh
* Theodore Freeman, Astronaut Group 3, Group 3 astronaut; killed in training jet accident—Haverford Township, Pennsylvania, Haverford
* Terry Hart, NASA astronaut—Pittsburgh
* James Irwin, Apollo 15—Pittsburgh
* Glynn Lunney, NASA engineer—Old Forge, Lackawanna County, Pennsylvania, Old Forge
* David Medved, trained astronaut and physicist—Philadelphia
* Paul W. Richards, Space Shuttle, Shuttle and International Space Station, ISS astronaut—Dunmore, Pennsylvania, Dunmore
* Patricia Hilliard Robertson, List of astronauts by selection#1998, 1998 Astronaut Group—killed in private airplane accident—Indiana, Pennsylvania, Indiana
* Daniel M. Tani, engineer, NASA astronaut—Ridley Park, Pennsylvania, Ridley Park
* Joseph A. Walker, USAF/NASA astronaut, United States' seventh man in space—Washington, Pennsylvania
* Paul J. Weitz, Skylab 2, Skylab and Shuttle astronaut— Erie

Athletes

"HOF" = Hall of Fame
; A–B

* John Abramovic, professional basketball player— Pittsburgh
* Cal Abrams (1924–1997), Major League Baseball player—Philadelphia, Pennsylvania, Philadelphia
* Matt Adams, professional baseball player—Philipsburg, Centre County, Pennsylvania, Philipsburg
* Herb Adderley, HOF professional football player—Philadelphia
* Eddie Alvarez, professional mixed martial artist—Philadelphia
* Rubén Amaro Jr. (born 1965), Major League Baseball player, general manager, and coach—Philadelphia
* Joe Amato (dragster driver), Joe Amato, professional drag racer—Old Forge, Lackawanna County, Pennsylvania, Old Forge
* John Andretti, NASCAR driver— Bethlehem
* Marco Andretti, auto racing driver—Nazareth, Pennsylvania, Nazareth
* Michael Andretti, auto racing driver—Bethlehem
* Kurt Angle, professional wrestler, Olympic gold medalist in freestyle wrestling—Pittsburgh
* Paul Arizin, HOF professional basketball player—Philadelphia
* LaVar Arrington, professional football player—Pittsburgh
* Cameron Artis-Payne, professional football player— Harrisburg
* Al Babartsky, professional football player—Shenandoah, Pennsylvania, Shenandoah
* Bob Babich (American football coach), Bob Babich, professional football coach—Aliquippa, Pennsylvania, Aliquippa
* Kayla Bashore, Olympic field hockey player—Hamburg, Pennsylvania, Hamburg
* Ralph Baker (linebacker), Ralph Baker, professional football player—Lewistown, Pennsylvania, Lewistown
*Saquon Barkley, professional football player—Coplay, Pennsylvania, Coplay
* Charlie Batch, professional football player—Homestead, Pennsylvania, Homestead
* William Beatty (American football), William Beatty, professional football player—York, Pennsylvania, York
* Aaron Beasley, professional football player—Pottstown, Pennsylvania, Pottstown
* Joe Beimel, professional baseball player—Elk County, Pennsylvania, Kersey
* Stan Belinda, professional baseball player—Huntingdon, Pennsylvania, Huntingdon
* Bert Bell, professional football commissioner—Philadelphia
* Brad Benson, professional football player— Altoona
* Norm Benning, NASCAR driver—Level Green, Pennsylvania, Level Green
* Jesse Biddle, professional baseball player—Philadelphia
* Fred Biletnikoff, HOF professional football player— Erie
* Steve Bilko, professional baseball player—Nanticoke, Pennsylvania, Nanticoke
* Adam Bisnowaty (born 1993), professional football player—Pittsburgh
* Steve Blackman, professional wrestler—Annville, Pennsylvania, Annville
* DeJuan Blair, professional basketball player—Pittsburgh
* George Blanda, HOF professional football player—Youngwood, Pennsylvania, Youngwood
* Chaim Bloom (born 1983), Chief Baseball Officer for the Boston Red Sox
* Charlie Bolling, professional golfer—Rosemont, Pennsylvania, Rosemont
* Sam Bowie, professional basketball player—Lebanon, Pennsylvania, Lebanon
* Jerry Boyarsky, professional football player—Scott Township, Lackawanna County, Pennsylvania, Scott Township
* Tyler Boyd (American football), Tyler Boyd, professional football player–Clairton, Pennsylvania, Clairton
* Kyle Brady, professional football player—Camp Hill, Pennsylvania, Camp Hill
* Sid Bream, professional baseball player—Mount Holly Springs, Pennsylvania, Mount Holly Springs
* Steve Breaston, professional football player—North Braddock, Pennsylvania, North Braddock
* Gustave Brickner, extreme swimmer—Charleroi, Pennsylvania, Charleroi
* Tom Brookens, professional baseball player—Chambersburg, Pennsylvania, Chambersburg
* Corey Brown (American football), Corey Brown, professional football player—Philadelphia
* Gary Brown (running back), Gary Brown, professional football player—Williamsport, Pennsylvania, Williamsport
* John Brown (American football, born 1891), John Brown, HOF college football player—Canton, Pennsylvania, Canton
* Philly Brown, professional football player—Upper Darby Township, Delaware County, Pennsylvania, Upper Darby
* Scott Brunner (American football), Scott Brunner, professional football player—Sellersville, Pennsylvania, Sellersville
* Kobe Bryant, professional basketball player—Lower Merion Township, Montgomery County, Pennsylvania, Lower Merion Township
* Taylor Buchholz, professional baseball player—Lower Merion Township
* Ryan Buchter, professional baseball player— Reading
* Marc Bulger, professional football player—Pittsburgh
* Leroy Burrell, track and field—Lansdowne, Pennsylvania, Lansdowne
* Rasual Butler, professional basketball player—Philadelphia
* Nate Byham, NFL tight end—Franklin, Pennsylvania, Franklin
* Axtell J. Byles, NFL Player—Titusville, Pennsylvania, Titusville

; C–D

* Alex Cabrera, professional baseball player—Lebanon, Pennsylvania, Lebanon
* Ray Caldwell, professional baseball player—McKean County, Pennsylvania, McKean County
* John Calipari, college basketball coach—Moon Township, Pennsylvania, Moon Township
* Roy Campanella, HOF professional baseball player—Philadelphia
* Russ Canzler, professional baseball player—Berwick, Pennsylvania, Berwick
* John Cappelletti, professional football player—Upper Darby, Pennsylvania, Upper Darby
* P. J. Carlesimo, professional basketball coach— Scranton
* Nate Carr, Olympic bronze medalist in freestyle wrestling— Erie
*Tony Carr (basketball), Tony Carr (born 1997), basketball player in the Israeli Premier Basketball League-Philadelphia
* Pete Carril, HOF college basketball coach— Bethlehem
* Matt Carroll (basketball), Matt Carroll, professional basketball player—Pittsburgh
* Len Chappell, professional basketball player—Portage, Pennsylvania, Portage
* Wilt Chamberlain, HOF professional basketball player—Philadelphia
* Barry Church, professional football player—Pittsburgh
* Nestor Chylak, professional baseball umpire—Olyphant, Pennsylvania, Olyphant
* Bruce Clark (American football), Bruce Clark, professional football player—New Castle, Pennsylvania, New Castle
* Bryan Cohen (born 1989), American-Israeli professional basketball player—Philadelphia
* Colby Cohen (born 1989), professional ice hockey player—Villanova, Pennsylvania, Villanova
* Jake Cohen (born 1990), American-Israeli professional basketball player—Bryn Mawr, Pennsylvania, Bryn Mawr
* Julia Cohen (born 1989), tennis player—Philadelphia
* Billy Conn, professional boxer—Pittsburgh
* James Conner (American football), James Conner, professional football player—Erie, Pennsylvania
* Harry Coveleski, professional baseball player—Shamokin, Pennsylvania, Shamokin
* Stan Coveleski, HOF baseball player—Shamokin, Pennsylvania, Shamokin
* Fran Crippen, swimmer—Conshohocken, Pennsylvania, Conshohocken
* Maddy Crippen, Olympic swimmer—Conshohocken
* Tom Clements, professional football coach—McKees Rocks, Pennsylvania, McKees Rocks
* Gary Collins (American football), Gary Collins, professional football player—Williamstown, Pennsylvania, Williamstown
* Joe Collins, professional baseball player— Scranton
* Kerry Collins, professional football player—Lebanon, Pennsylvania, Lebanon
* Marques Colston, professional football player—Susquehanna Township, Dauphin County, Pennsylvania, Susquehanna Township
* Dan Conners, professional football player—St. Mary's, Pennsylvania, St. Mary's
* Dan Connor (American football), Dan Connor, professional football player—Wallingford, Pennsylvania, Wallingford
* Mark Corey, professional baseball player—Austin, Pennsylvania, Austin
* Mike Costanzo, professional baseball player—Philadelphia
* Jim Covert, professional football player—Conway, Pennsylvania, Conway
* Bill Cowher, professional football coach—Crafton, Pennsylvania, Crafton
* Billy Cox, professional baseball player—Newport, Pennsylvania, Newport
* Mike Cox (fullback), Mike Cox, professional football player—Lewisberry, Pennsylvania, Lewisberry
* Channing Crowder, professional football player—State College, Pennsylvania, State College
* Chris Culliver, professional football player—Philadelphia
* David Curtiss (swimmer), David Curtiss, competitive swimmer—Yardley, Pennsylvania, Yardley
* Chuck Daly, HOF professional basketball coach—Kane, Pennsylvania, Kane
* Bob Davie (American football), Bob Davie, college football coach—Moon Township, Pennsylvania, Moon Township
* Ernie Davis, HOF college football player—New Salem-Buffington, Pennsylvania, New Salem-Buffington
* Phil Davis (fighter), Phil Davis, Ultimate Fighting Championship, UFC fighter— Harrisburg
* Darrell Dess, professional football player—New Castle, Pennsylvania, New Castle
* James Develin, professional football player— Boyertown
* Dorin Dickerson, professional football player—Imperial-Enlow, Pennsylvania, Imperial
* Keir Dillon, professional snowboarder—East Stroudsburg, Pennsylvania, East Stroudsburg
* Mike Ditka, HOF professional football player and coach—Aliquippa, Pennsylvania, Aliquippa
* Randy Dobnak, professional baseball player—South Park Township, Allegheny County, Pennsylvania, South Park
* Tim Donaghy, professional basketball referee—Havertown, Pennsylvania, Havertown
* Aaron Donald, professional football player—Pittsburgh
* Jakim Donaldson (born 1983), basketball player in the Israeli Basketball Premier League–Pittsburgh
* Keith Dorney, professional football player—Emmaus, Pennsylvania, Emmaus
* Tony Dorsett, HOF professional football player—Hopewell Township, Beaver County, Pennsylvania, Hopewell Township
* Forrest Douds, Forrest "Jap" Douds, professional football player and coach—Rochester, Pennsylvania, Rochester
* Shane Douglas, professional wrestler—Pittsburgh
* Jim Drucker (born 1952/1953), former Commissioner of the Continental Basketball Association, former Commissioner of the Arena Football League, and founder of NewKadia Comics—Plymouth Meeting, Pennsylvania, Plymouth Meeting
* Jeff Dugan, professional football player—Pittsburgh
* Pete Duranko, professional football player— Johnstown
* Jimmy Dykes, professional baseball player—Philadelphia
* Stanley Dziedzic, Olympic bronze medalist in freestyle wrestling—Allentown, Pennsylvania, Allentown

; E–G

* Bill Eadie, professional wrestler—Brownsville, Pennsylvania, Brownsville
* Kyle Eckel, professional football player—Philadelphia
* Josh Edgin, professional baseball player—Three Springs, Pennsylvania, Three Springs
* Wayne Ellington, professional basketball player—Wynnewood, Pennsylvania, Wynnewood
* Cody Eppley, professional baseball player—Dillsburg, Pennsylvania, Dillsburg
* Jahri Evans, professional football player—Philadelphia
* Tyreke Evans, professional basketball player—Chester
* Tim Federowicz, professional baseball player— Erie
* Bill Ferrario, professional football player— Scranton
* Randy Fichtner, professional football coach—Meadville, Pennsylvania, Meadville
* Frank Filchock, professional football player and coach—Greene County, Pennsylvania, Greene County
* D'or Fischer (born 1981), Israeli-American basketball player in the Liga Leumit (basketball), Israeli National League—Philadelphia
* Joe Flacco, professional football player—Philadelphia
* Pat Flaherty (American football), Pat Flaherty, professional football coach—McSherrystown, Pennsylvania, McSherrystown
* Hali Flickinger, Olympic swimmer—York County, Pennsylvania, York County
* Andre Fluellen, professional football player—Philadelphia
* Tom Flynn (American football), Tom Flynn, professional football player—Verona, Pennsylvania, Verona
* Nellie Fox, HOF professional baseball player—St. Thomas Township, Pennsylvania, St. Thomas Township
* Terry Francona, professional baseball manager—New Brighton, Pennsylvania, New Brighton
* Tito Francona, professional baseball player—New Brighton, Pennsylvania, New Brighton
* John Frank (tight end), John Frank (born 1962), professional football player—Pittsburgh
* Buck Freeman, professional baseball player—Catasauqua, Pennsylvania, Catasauqua
* Gus Frerotte, professional football player—Kittanning, Pennsylvania, Kittanning
* Carl Furillo, professional baseball player–Stony Creek Mills, Pennsylvania, Stony Creek Mills
* Jim Furyk, professional golfer— Lancaster
* Rich Gannon, professional football player—Philadelphia
* Ryan Garko, professional baseball player—Pittsburgh
* Jason Garrett, professional football coach—Abington Township, Montgomery County, Pennsylvania, Abington
* John Garrett (American football coach), John Garrett, professional football coach—Danville, Pennsylvania, Danville
* Eddie George, professional football player—Abington Township, Montgomery County, Pennsylvania, Abington Township
* Sam Gerson, Olympic silver medalist in freestyle wrestling—Philadelphia
* Sean Gilbert, professional football player—Aliquippa
* Armen Gilliam, professional basketball player—Bethel Park, Pennsylvania, Bethel Park
* Garry Gilliam, professional football player—Harrisburg
* Kimberly Glass, professional volleyball player— Lancaster
* Tom Gola, HOF basketball player—Philadelphia
* Robbie Gould, professional football player—Jersey Shore, Pennsylvania, Jersey Shore
* Bruce Gradkowski, professional football player—Pittsburgh
* Gino Gradkowski, professional football player—Pittsburgh
* Aaron Gray, professional basketball player—Emmaus
* Dick Gray, professional baseball player—Jefferson, Greene County, Pennsylvania, Jefferson
* Al Gionfriddo, professional baseball player—Dysart, Pennsylvania, Dysart
* Ken Griffey Jr., professional baseball player—Donora, Pennsylvania, Donora
* Ken Griffey Sr., professional baseball player—Donora, Pennsylvania, Donora
* Russ Grimm, professional football player—Scottdale, Pennsylvania, Scottdale
* Dick Groat, professional baseball player—Wilkinsburg, Pennsylvania, Wilkinsburg
* Randy Grossman (born 1952), professional football player—Haverford Township
* Billy Kidman, Peter Gruner, professional wrestler, ring name Billy Kidman—Allentown, Pennsylvania, Allentown
* Brandon Guyer, professional baseball player— West Chester

; H–K

* Jack Ham, professional football player—Johnstown
* Richard Hamilton (basketball), Richard Hamilton, professional basketball player
* Brendan Hansen, Olympic gold medal swimmer—Haverford Township, Pennsylvania, Haverford Township
* Marvin Harrison, professional football player—Philadelphia
* Ray Harroun, winner of the first Indianapolis 500—Titusville, Pennsylvania, Titusville
* Leon Hart, professional football player—Pittsburgh
* Jim Haslett, professional football player and coach—Pittsburgh
* Andrew Hawkins, professional football player— Johnstown
* Artrell Hawkins, professional football player—Johnstown
* Don Heffner, professional baseball player and manager—Rouzerville, Pennsylvania, Rouzerville
* Chris Heisey, professional baseball player—Mount Joy, Pennsylvania, Mount Joy
* John Heisman, football player, namesake of trophy—Titusville, Pennsylvania, Titusville
* Gerald Henderson Jr., professional basketball player—Merion, Pennsylvania, Merion
* Chad Henne, professional football player—Wyomissing, Pennsylvania, Wyomissing
* Jake Herbert, Olympic freestyle wrestler—Pittsburgh
* Tom Herr, professional baseball player and manager— Lancaster
* Mark Herzlich, professional football player—Wayne, Pennsylvania, Wayne
* Cameron Heyward, professional football player—Pittsburgh
* Eric Hicks (American football), Eric Hicks, professional football player— Erie
* Jordan Hill (American football), Jordan Hill, professional football player— Harrisburg
* Shawn Hillegas, professional baseball player—South Fork, Pennsylvania, South Fork
* Darrun Hilliard, professional basketball player
* Al Holbert, professional auto racer—Warrington Township, Bucks County, Pennsylvania, Warrington
* Larry Holmes, HOF professional boxer— Easton
* J. J. Hoover, professional baseball player—Elizabeth, Pennsylvania, Elizabeth
* Bernard Hopkins, professional boxer—Philadelphia
* Jeff Hostetler, professional football player—Hollsopple, Pennsylvania, Hollsopple
* Art Howe, professional baseball player and manager—Pittsburgh
* Gene Huey, professional football player—Uniontown, Pennsylvania, Uniontown
* Henry Hynoski, professional football player—Elysburg, Pennsylvania, Elysburg
* Jerald Ingram, professional football coach—Beaver, Pennsylvania, Beaver
* Qadry Ismail, professional football player—Wilkes-Barre, Pennsylvania, Wilkes-Barre
* Raghib Ismail, professional football player—Wilkes-Barre
* Marc Jackson, professional basketball player—Philadelphia
* Marlin Jackson, professional football player—Sharon
* Reggie Jackson, HOF professional baseball player—Wyncote, Pennsylvania, Wyncote
* Brook Jacoby, professional baseball player—Philadelphia
* Hughie Jennings, professional baseball player—Pittston, Pennsylvania, Pittston
* Larry Johnson (running back), Larry Johnson, professional football player—State College, Pennsylvania, State College
* Derrick Jones Jr., professional basketball player—Chester
* Eddie Jones (basketball), Eddie Jones, professional basketball player—Philadelphia
* Kevin Jones (BMX rider), Kevin Jones, professional BMX rider—York, Pennsylvania, York
* Sage Karam, professional racing driver—Nazareth, Pennsylvania, Nazareth
* George Karl, professional basketball coach—Penn Hills Township, Allegheny County, Pennsylvania, Penn Hills
* Nate Karns, professional baseball player—Franklin, Pennsylvania, Franklin
* Don Kelly (baseball), Don Kelly, professional baseball player—Butler
* Jim Kelly, HOF professional football player—Bradys Bend Township, Pennsylvania, Bradys Bend Township
* Pat Kelly (infielder), Pat Kelly, professional baseball player—Philadelphia
* Ray Kemp, professional football player—Cecil Township, Washington County, Pennsylvania, Cecil Township
* Billy Kidman (ring name), professional wrestler—Allentown
* Ethan Kilmer, professional football player—Wyalusing, Pennsylvania, Wyalusing
* Bucko Kilroy, professional football player and coach—Philadelphia
* Betsy King, HOF professional golfer— Reading
* Steve Kline (left-handed pitcher), Steve Kline, professional baseball player—Winfield, Pennsylvania, Winfield
* Cary Kolat, freestyle wrestler, two-time world medalist—Rices Landing, Pennsylvania, Rices Landing
* Dan Koppen, professional football player—Whitehall Township, Lehigh County, Pennsylvania, Whitehall Township
* Josh Koscheck, professional mixed martial artist—Waynesburg, Pennsylvania, Waynesburg
* Kristy Kowal, Olympic swimmer— Reading
* Bruce Kozerski, professional football player—Plains Township, Pennsylvania, Plains Township
* Erik Kratz, professional baseball player—Telford, Pennsylvania, Telford
*Julian Krinsky, tennis player-Philadelphia
* John Kuhn, professional football player—Dover, Pennsylvania, Dover

; L–M

* Floyd Landis, professional cyclist— Lancaster
* Tom Lasorda, HOF professional baseball manager— Norristown
* Howard Lassoff (1955–2013), American-Israeli basketball player
* Ty Law, professional football player—Aliquippa, Pennsylvania, Aliquippa
* Sean Lee, professional football player—Pittsburgh
* Don LeJohn, professional baseball manager—Daisytown, Pennsylvania, Daisytown
* Matt Lengel, professional football player—Mechanicsburg, Pennsylvania, Mechanicsburg
* Chad Levitt, professional football player—Cheltenham, Pennsylvania, Cheltenham
* Dion Lewis, professional football player—Penn Hills, Pennsylvania, Penn Hills
* Grant Lewis, professional ice hockey player—Upper St. Clair, Pennsylvania, Upper St. Clair
* Ralph Lewis (basketball), Ralph Lewis, professional basketball player and coach—Philadelphia
* Ryan Lexer (born 1976), American-Israeli basketball player—Philadelphia
* Tara Lipinski, Olympic gold medalist in figure skating—Philadelphia
* Kyle Lowry, professional basketball player—Philadelphia
* Maurice Lucas, professional basketball player—Pittsburgh
* Johnny Lujack, HOF professional football player—Connellsville, Pennsylvania, Connellsville
* Chloe Lukasiak, actor, featured dancer on ''Dance Moms''—Churchill, Pennsylvania, Churchill ( Pittsburgh/Mars, Pennsylvania, Mars)
* Sparky Lyle professional baseball player—Reynoldsville, Pennsylvania, Reynoldsville
* Joe Maddon, professional baseball manager—Hazleton, Pennsylvania, Hazleton
* Brooke Makler (1951–2010), Olympic fencer
* Paul Makler Jr. (born 1946), Olympic fencer
* Paul Makler Sr. (born 1920), Olympic fencer
* Ryan Malone, professional hockey player—Upper St. Clair, Pennsylvania, Upper St. Clair
* Greg Manusky, professional football player—Dallas, Pennsylvania, Dallas
* Bam Margera, professional skateboarder— West Chester
* Pete Maravich, HOF professional basketball player—Aliquippa
* Dan Marino, HOF professional football player—Pittsburgh
* Brandon Marshall, professional football player—Pittsburgh
* Donyell Marshall, professional basketball player—Reading
* Tim Masthay, professional football player—Pittsburgh
* Christy Mathewson, HOF professional baseball player—Factoryville, Pennsylvania, Factoryville
* Michael R. Matz, Olympic equestrian and thoroughbred trainer—Collegeville, Pennsylvania, Collegeville
* Pat McAfee, professional football player—Plum, Pennsylvania, Plum
* Matt McBride, professional baseball player—Bethlehem
* Ed McCaffrey, professional football player—Waynesboro, Pennsylvania, Waynesboro
* Joe McCarthy (manager), Joe McCarthy, HOF baseball manager—Philadelphia
* Mike McCarthy, American football coach—Pittsburgh
* John McDermott (golfer), John J. McDermott, professional golfer—Philadelphia
* Jameel McClain, professional football player—Philadelphia
* Robert McClain, professional football player—Philadelphia
* LeSean McCoy, professional football player—Harrisburg
* Mike McCoy (defensive tackle), Mike McCoy, professional football player—Erie
* Muffet McGraw, college basketball coach—Pottstown, Pennsylvania, Pottstown
* Aaron Mckie, professional basketball player—Philadelphia
* Josephine McKim, Olympic swimming gold medalist—Oil City, Pennsylvania, Oil City
* Brandon McManus, professional football player—Philadelphia
* Rocco Mediate, professional golfer—Greensburg, Pennsylvania, Greensburg
* Mike Mentzer, professional bodybuilder, bodybuilder, 1979 Mr. Olympia—Ephrata, Pennsylvania, Ephrata
* Devin Mesoraco, professional baseball player—Punxsutawney, Pennsylvania, Punxsutawney
* Lou Michaels, professional football player—Swoyersville, Pennsylvania, Swoyersville
* Walt Michaels, pro football player and coach—Swoyersville, Pennsylvania, Swoyersville
* Matt Millen, professional football player—Whitehall Township, Lehigh County, Pennsylvania, Whitehall Township
* Abby Lee Miller, star of Pittsburgh-based ''Dance Moms'' and owner of Abby Lee Dance Company—Penn Hills
* Eric Milton, professional baseball pitcher—Bellefonte, Pennsylvania, Bellefonte
* Cuttino Mobley, professional basketball player—Philadelphia
* Earl Monroe, HOF professional basketball player—Philadelphia
* Joe Montana, HOF professional football player—New Eagle, Pennsylvania, New Eagle
* Nick Moody, professional football player—Wyncote, Pennsylvania, Wyncote
* Charles Morgan (American football), Charles Morgan, professional football player—Allentown
* Lenny Moore, HOF professional football player— Reading
* Michael Moorer, professional boxer—Monessen, Pennsylvania, Monessen
* Marcus Morris (basketball), Marcus Morris, professional basketball player—Philadelphia
* Markieff Morris, professional basketball player—Philadelphia
* Mercury Morris, professional football player—Pittsburgh
* Jamie Moyer, professional baseball player—Sellersville, Pennsylvania, Sellersville
* Terry Mulholland, professional baseball player—Uniontown, Pennsylvania, Uniontown
* Mike Munchak, professional football player— Scranton
* Ryan Mundy, professional football player—Pittsburgh
* James Mungro, professional football player—East Stroudsburg, Pennsylvania, East Stroudsburg
* Flip Murray, professional basketball player—Philadelphia
* Stan Musial, HOF professional baseball player—Donora, Pennsylvania, Donora
* Mike Mussina, professional baseball player—Montoursville, Pennsylvania, Montoursville

; N–R

* Joe Namath, HOF professional football player—Beaver Falls, Pennsylvania, Beaver Falls
* Bridget Namiotka (born 1990), pair skater
* Ryan Nassib, professional football player— West Chester
* Jameer Nelson, professional basketball player—Chester
* Lucas Nix, professional football player—Clairton, Pennsylvania, Clairton
* Jordan Norwood, professional football player—State College, Pennsylvania, State College
* Marty Nothstein, professional cyclist, 2000 Summer Olympics, 2000 Olympics gold medalist—Emmaus, Pennsylvania, Emmaus
* Jared Odrick, professional football player—Lebanon, Pennsylvania, Lebanon
* Bo Orlando, professional football player—Berwick, Pennsylvania, Berwick
* Ben Olsen, professional soccer player and coach—Middletown, Dauphin County, Pennsylvania, Middletown
* Joe Ostrowski, professional baseball player—West Wyoming, Pennsylvania, West Wyoming
* Ed Ott, professional baseball player—Muncy, Pennsylvania, Muncy
* Doug Overton, professional basketball coach—Philadelphia, Pennsylvania
* Billy Owens, professional basketball player—Carlisle, Pennsylvania, Carlisle
* Arnold Palmer, HOF professional golfer—Latrobe, Pennsylvania, Latrobe
* George Parros, professional hockey player—Washington, Pennsylvania, Washington
* Sean Payton, professional football head coach for the New Orleans Saints—Philadelphia
* Todd Peck, professional racing driver—Glenville, Pennsylvania, Glenville
* Corey Peters, professional football player—Pittsburgh
* Zach Pfeffer (born 1995), soccer player—Dresher
* Mike Piazza, HOF professional baseball player— Norristown
* Bernard Pierce, professional football player—Ardmore, Pennsylvania, Ardmore
* Jason Pinkston, professional football player—Pittsburgh
* Lousaka Polite, professional football player—North Braddock, Pennsylvania, North Braddock
* Paul Posluszny, professional football player—Hopewell Township, Beaver County, Pennsylvania, Hopewell Township
* Abner Charles Powell, professional baseball player, owner, innovator—Shenandoah, Pennsylvania, Shenandoah
* Terrelle Pryor, professional football player—Jeannette, Pennsylvania, Jeannette
* Justin Pugh, professional football player—Holland, Pennsylvania, Holland
* Christian Pulisic, professional soccer player—Hershey, Pennsylvania, Hershey
* Andre Reed, HOF professional football player—Allentown
* Dylan Reese (born 1984), NHL ice hockey player—Pittsburgh
* Frank Reich, professional football player—Lebanon, Pennsylvania, Lebanon
* Nolan Reimold, professional baseball player—Greenville, Pennsylvania, Greenville
* Nicole Reinhart, professional cyclist—Macungie, Pennsylvania, Macungie
* Rocky Reynolds, professional wrestler—Titusville, Pennsylvania, Titusville
* Darrelle Revis, professional football player—Aliquippa, Pennsylvania, Aliquippa
* Mike Richter, professional hockey player—Abington Township, Montgomery County, Pennsylvania, Abington
* Garth Rickards, professional racing driver—Mechanicsburg, Pennsylvania, Mechanicsburg
* Adam Rippon, Olympic bronze medalist in figure skating—Clarks Summit, Pennsylvania, Clarks Summit
* Jon Ritchie, professional football player—Mechanicsburg, Pennsylvania, Mechanicsburg
* Bill Robinson (outfielder), Bill Robinson, professional baseball player, coach— McKeesport
* Ed Roebuck, professional baseball player—East Millsboro, Pennsylvania, East Millsboro
* Malik Rose, professional basketball player—Philadelphia
* Mike Rosenthal (born 1977), NFL football player—Pittsburgh
* Tim Ruddy, professional football player—Dunmore, Pennsylvania, Dunmore
* Bobby Ryan, professional ice hockey player—Philadelphia
* Matt Ryan (American football), Matt Ryan, professional football player—Exton, Pennsylvania, Exton

; S–Z

* Brandon Saad, professional hockey player—Pittsburgh
* Jack Sack (1902–1980), football player and coach
* John Salmons, professional basketball player—Philadelphia
* Bruno Sammartino, professional wrestler—Pittsburgh
* Bob Sanders, professional football player—Erie
* Jerry Sandusky, college football coach—Washington, Pennsylvania, Washington
* Carl Sawatski, professional baseball player—Shickshinny, Pennsylvania, Shickshinny
* Matt Schaub, professional football player—Pittsburgh
* Steve Schlachter (born 1954), American-Israeli basketball player—Plymouth Meeting
* Allison Schmitt, Olympic Swimming (sport), swimmer– Pittsburgh
* Brian Schneider, professional baseball player—Northampton, Pennsylvania, Northampton
* Marty Schottenheimer, professional football coach
* Mike Scioscia, professional baseball player and manager—Morton, Pennsylvania, Morton
* Coleman Scott, Olympic bronze medalist in freestyle wrestling—Waynesburg, Pennsylvania, Waynesburg
* Da'Rel Scott, professional football player—Conshohocken, Pennsylvania, Conshohocken
* Vic Seixas (born 1923), professional Hall of Fame tennis player
*Nate Sestina (born 1997), basketball player in the Israeli Basketball Premier League
* Mustafa Shakur, professional basketball player—Philadelphia
* Bobby Shantz, professional baseball player—Pottstown, Pennsylvania, Pottstown
* Kirk Shelmerdine, NASCAR crew chief and driver— Philadelphia
* Jean Shiley, Olympic track and field gold medalist— Harrisburg
* Dick Shiner, professional football player—Lebanon, Pennsylvania, Lebanon
* A. Q. Shipley, professional football player—Coraopolis, Pennsylvania, Coraopolis
* Tom Skladany, professional football player—Bethel Park, Pennsylvania, Bethel Park
* Greg Skrepenak, professional football player—Wilkes Barre, Pennsylvania, Wilkes Barre
* Steve Slaton, professional football player—Levittown, Pennsylvania, Levittown
* Kevin Slowey, professional baseball player—Upper St. Clair Township, Allegheny County, Pennsylvania, Upper St. Clair
* Musa Smith, professional football player—New Bloomfield, Pennsylvania, New Bloomfield
* Garrett Smithley, professional racing driver—Ligionier, Pennsylvania, Ligionier
* Gene Snitsky, professional wrestler—Nesquehoning, Pennsylvania, Nesquehoning
* Frank Spellman (1922–2017), Olympic champion weightlifter—Malvern, Philadelphia, York
* Jimmy Spencer (racing driver), Jimmy Spencer, professional racecar driver—Berwick, Pennsylvania, Berwick
* Shawntae Spencer, professional football player—Rankin, Pennsylvania, Rankin
* Eddie Stanky, professional baseball player and manager—Philadelphia
* Larod Stephens-Howling, professional football player— Johnstown
* Mark Stepnoski, professional football player— Erie
* Tony Stewart (American football), Tony Stewart, professional football player—Allentown
* Devin Street, professional football player—Bethlehem
* Ross Stripling, professional baseball player—Blue Bell, Pennsylvania, Blue Bell
* Big John Studd, professional wrestler—Butler
* Joe Stydahar, professional football player and coach—Kaylor, Pennsylvania, Kaylor
* Matt Suhey, professional football player—Bellefonte, Pennsylvania, Bellefonte
* Bob Sura, professional basketball player—Wilkes-Barre
* Bruce Sutter, HOF professional baseball player— Lancaster
* Chuck Tanner, professional baseball player and manager—New Castle, Pennsylvania, New Castle
* Jason Taylor (American football), Jason Taylor, professional football player—Pittsburgh
* Ray Tesser, professional football player—Titusville, Pennsylvania, Titusville
* Walter Tewksbury, Olympian track and field athlete—Ashley, Pennsylvania, Ashley
* Jaimie Thomas, professional football player— Harrisburg
* Myles Thomas, professional baseball player—State College, Pennsylvania, State College
* Carol Semple Thompson, amateur golfer—Sewickley, Pennsylvania, Sewickley
* Jim Thorpe, various—Carlisle, only connected posthumously to Jim Thorpe, Pennsylvania, Jim Thorpe
* Jim Tomsula, professional football coach—Homestead, Pennsylvania, Homestead
* Wallace Triplett, professional football player—Cheltenham Township, Montgomery County, Pennsylvania, Cheltenham Township
* Charley Trippi, HOF professional football player—Pittston, Pennsylvania, Pittston
* Bob Tucker (American football), Bob Tucker, professional football player—Hazleton, Pennsylvania, Hazleton
* Emlen Tunnell, HOF professional football player—Bryn Mawr, Pennsylvania, Bryn Mawr
* Dave Twardzik, professional basketball player—Middletown, Dauphin County, Pennsylvania, Middletown
* R.J. Umberger, professional hockey player—Pittsburgh
* Johnny Unitas, HOF professional football player—Pittsburgh
* Mickey Vernon, professional baseball player—Marcus Hook, Pennsylvania, Marcus Hook
* Iosif Vitebskiy (born 1938), Soviet Ukrainian Olympic medalist and world champion épée fencer and fencing coach—Philadelphia
* Honus Wagner, HOF professional baseball player—Chartiers Township, Pennsylvania, Chartiers Township
* Dion Waiters, professional basketball player—Philadelphia
* Christian Walker (baseball), Christian Walker, professional baseball player— Norristown
* Neil Walker (baseball), Neil Walker, professional baseball player—Pittsburgh
* Art Wall Jr., professional golfer—Honesdale, Pennsylvania, Honesdale
* Rasheed Wallace, professional basketball player—Philadelphia
* Ed Walsh, HOF professional baseball player—Plains Township, Pennsylvania, Plains Township
* Joe Walton, professional football coach—Beaver Falls, Pennsylvania, Beaver Falls
* Hakim Warrick, professional basketball player—Philadelphia
* Earl Watford, professional football player—Philadelphia
* Kenny Watson (American football), Kenny Watson, professional football player—Harrisburg
* Ricky Watters, professional football player—Harrisburg
* Bobby Weaver, Olympic gold medal freestyle wrestler– Easton
* Reggie Wells, professional football player—South Park, Pennsylvania, South Park
* Johnny Weir, professional and Olympic figure skater—Coatesville, Pennsylvania, Coatesville
* Randy White (American football), Randy White, HOF professional football player—Pittsburgh
* Brian Williams (center), Brian Williams, professional football player—Mt. Lebanon, Pennsylvania, Mt. Lebanon
*Earl Williams (basketball player), Early Williams (born 1951), American-Israeli basketball player
* Lauryn Williams, Summer and Winter Olympic medalist—Rochester, Pennsylvania, Rochester
* Josh Wilson (baseball), Josh Wilson, professional baseball player—Mt. Lebanon
* Kris Wilson (American football), Kris Wilson, professional football player—Harrisburg
* Coy Wire, professional football player—Camp Hill, Pennsylvania, Camp Hill—Cedar Cliff
* Stefen Wisniewski, professional football player—Pittsburgh
* Lee Woodall, professional football player—Carlisle, Pennsylvania, Carlisle
* Tom Woodeshick, professional football player—Wilkes-Barre
* John Woodruff (athlete), John Woodruff, Olympic gold medalist in track and field—Connellsville, Pennsylvania, Connellsville
* Blidi Wreh-Wilson, professional football player—Edinboro, Pennsylvania, Edinboro
* Frank Wycheck, professional football player—Philadelphia
*Michael Young (basketball, born 1994), Michael Young (born 1994), basketball player for Ironi Nahariya of the Israeli Basketball Premier League—Pittsburgh
* Stephen Zack (born 1992), basketball player
* Maddie Ziegler, actor, featured dancer on ''Dance Moms''— Murrysville
* Mackenzie Ziegler, actor, featured dancer on ''Dance Moms''—Murrysville

Authors, playwrights, and writers

* Edward Abbey—Indiana, Pennsylvania, Indiana
* Louisa May Alcott—Germantown, Philadelphia, Pennsylvania, Germantown
* Lloyd Alexander—Philadelphia
* George Anastasia—Philadelphia
* Maxwell Anderson-Atlantic, Pennsylvania, Atlantic
* Poul Anderson—Bristol, Pennsylvania, Bristol
* Janet Asimov—Ashland, Pennsylvania, Ashland
* Mary Canfield Ballard—Troy, Pennsylvania, Troy
* Samuel Barber— West Chester
* Donald Barthelme—Philadelphia
* Ellen Bass—Philadelphia
* John Batchelor—Bryn Mawr, Pennsylvania, Bryn Mawr / Lower Merion Township, Montgomery County, Pennsylvania, Lower Merion Township
* Mary Temple Bayard—Waynesburg, Pennsylvania, Waynesburg
* Adaline Hohf Beery–Hanover, Pennsylvania, Hanover
* Stan and Jan Berenstain—Philadelphia
* Ben Bova—Philadelphia
* Mary D. R. Boyd—Philadelphia
* Mrs. Findley Braden, Anna Braden—Montgomery, Pennsylvania, Montgomery
* Pearl S. Buck—Perkasie
* Charles Brockden Brown—Philadelphia
* Bebe Moore Campbell—Philadelphia
* Francesca Anna Canfield–—Philadelphia
* Rachel Carson— Springdale
* Diana Cavallo—Philadelphia
* Stephen Chbosky—Pittsburgh
* Helen Taggart Clark–Northumberland, Pennsylvania, Northumberland
* Mary M. Cohen—Philadelphia
* Marc Connelly— McKeesport
* Michael Connelly—Philadelphia
* Margaret Deland—Allegheny, Pennsylvania, Allegheny
* Annie Dillard—Pittsburgh
* Ella Hamilton Durley–Harrisville, Pennsylvania, Harrisville
* Tristan Egolf— Lancaster
* Robert Fagles—Philadelphia, Pennsylvania, Philadelphia
* Stephen Flaherty—Pittsburgh
* Harvey Flink—Centre Hall
* Tom Flynn (author), Tom Flynn— Erie
* Nancy Friday—Pittsburgh
* David Fulmer—Northumberland, Pennsylvania, Northumberland
* Todd Gallagher—Greensburg, Pennsylvania, Greensburg
* Walter B. Gibson—Philadelphia
* Carmen Gentile—New Kensington, Pennsylvania, New Kensington
* Jim Goad—Ridley Park, Pennsylvania, Ridley Park
* H.D. (Hilda Doolittle)— Bethlehem
* Oscar Hammerstein II—Doylestown, Pennsylvania, Doylestown
* Lucy Hamilton Hooper—Philadelphia
* Emeline Harriet Howe—West Hickory, Pennsylvania, West Hickory
* Kristin Hunter—Philadelphia
* Woody Jackson—Oil City, Pennsylvania, Oil City
* Thomas Allibone Janvier—Philadelphia
* Robert T. Jeschonek— Johnstown
* Kait Kerrigan—Kingston, Pennsylvania, Kingston
* Dean Koontz—Shippensburg, Pennsylvania, Everett
* David Leavitt—Pittsburgh
* Marguerite St. Leon Loud-Wysox, Pennsylvania, Wysox
* Bree Lowdermilk—Wallingford, Pennsylvania, Wallingford
* John D. MacDonald—Sharon
* Edith May (poet), Edith May—Philadelphia
* David McCullough—Pittsburgh
* Henry Meyer (poet), Henry Meyer—Centre County, Pennsylvania, Centre County
* James A. Michener—Doylestown, Pennsylvania, Doylestown
* Jason Miller (playwright), Jason Miller— Scranton
* Susanne Vandegrift Moore– Bucks County
* James Morrow—Philadelphia
* Lance Morrow—Philadelphia
* John O'Hara—Pottsville, Pennsylvania, Pottsville
* Ralph Peters—Pottsville, Pennsylvania, Pottsville / Schuylkill Haven, Pennsylvania, Schuylkill Haven
* Robert W. Peterson (writer), Robert W. Peterson—Warren, Pennsylvania, Warren
* Darryl Ponicsan—Shenandoah, Pennsylvania, Shenandoah
* Ezra Pound—Wyncote, Pennsylvania, Wyncote
* Conrad Richter—Pine Grove, Schuylkill County, Pennsylvania, Pine Grove
* Mary Rinehart—Pittsburgh
* Julia H. Scott–Sheshequin Township, Bradford County, Pennsylvania, Sheshequin
* Lisa Scottoline—Philadelphia
* Sara Shepard—Downingtown, Pennsylvania, Downingtown
* Dora Adele Shoemaker—Philadelphia
* Luella Dowd Smith–Sheffield, Massachusetts, Sheffield
* Martin Cruz Smith— Reading
* Stephen Sondheim—Doylestown, Pennsylvania, Doylestown
* Jerry Spinelli— Norristown
* Jerry Stahl—Pittsburgh
* Gertrude Stein—Allegheny, Pennsylvania, Allegheny
* Gerald Stern—Pittsburgh
* Wallace Stevens— Reading
* Ida Tarbell—Titusville, Pennsylvania, Titusville
* Bayard Taylor—Chester County, Pennsylvania, Chester County
* Eva Griffith Thompson–Jennersville, Pennsylvania, Jennersville
* John Updike— Reading
* Ellen Oliver Van Fleet—Troy, Pennsylvania, Troy
* Judith Vollmer—Pittsburgh
* Sarah Stokes Walton—Philadelphia
* Jeannette H. Walworth–—Philadelphia
* Joseph Wambaugh–—East Pittsburgh, Pennsylvania, East Pittsburgh
* Catharine H. Waterman—Philadelphia
* Lauren Weisberger—Allentown, Pennsylvania, Allentown
* John Edgar Wideman—Pittsburgh
* Marianne Wiggins— Lancaster
* August Wilson—Pittsburgh
* Owen Wister—Philadelphia
* Jeffrey Zaslow—Broomall, Pennsylvania, Broomall
* Calvin Ziegler—Rebersburg, Pennsylvania, Rebersburg

Computer scientists and mathematicians

* Scott Aaronson—Philadelphia
* John Backus—Philadelphia
* David A. Bader— Bethlehem
* Brendan Eich—Pittsburgh
* Martin Charles Golumbic— Erie
* Emil Grosswald—Narberth, Pennsylvania, Narberth
* William Draper Harkins—Titusville, Pennsylvania, Titusville
* Chad Hurley—Birdsboro, Pennsylvania, Birdsboro
* Oliver Dimon Kellogg—Linwood, Pennsylvania, Linwood
* Alan Kotok—Philadelphia
* Michael L. Littman—Philadelphia
* Alan Perlis—Pittsburgh
* Hilary Putnam—Philadelphia
* Jeffrey Shallit—Philadelphia
* George Stibitz—York, Pennsylvania, York
* E. Roy Weintraub—Philadelphia

Conservationists

* Charles Almanzo Babcock, Charles Babcock—Oil City, Pennsylvania, Oil City
* Rachel Carson— Springdale
* Paul R. Ehrlich—Germantown, Philadelphia, Germantown
* Inky Moore—Newville, Pennsylvania, Newville
* Joseph Rothrock—McVeytown, Pennsylvania, McVeytown
* Howard Zahniser—Franklin, Pennsylvania, Franklin

Criminals

* Mumia Abu-Jamal—Philadelphia
* George Banks (spree killer), George Banks—Wilkes-Barre
* Richard Baumhammers—Pittsburgh
* Angelo Bruno—Philadelphia
* Andrew Thomas DelGiorno—Philadelphia
* Mickey Duffy—Philadelphia
* Ira Einhorn—Philadelphia
* Caleb Fairley—Gulph Mills, Pennsylvania, Gulph Mills
* George Feigley—Harrisburg
* Eric Frein—Canadensis, Pennsylvania, Canadensis
* Kermit Gosnell—Philadelphia
* Gary M. Heidnik—Philadelphia
* Max Hoff (mobster), Maxie "Boo Boo" Hoff—Philadelphia
* Eddie James—Bristol, Pennsylvania, Bristol
* Joseph Kallinger—Philadelphia
* Timothy Krajcir—West Mahanoy Township, Schuylkill County, Pennsylvania, West Mahanoy
* Alec Devon Kreider—Lancaster County, Pennsylvania, Lancaster County
* Ignatius Lanzetta—Philadelphia
* Leo Lanzetta—Philadelphia
* John LaRocca—Indiana County, Pennsylvania, Indiana County
* Joey Merlino—Philadelphia
* Charles Carl Roberts— Lancaster
* Jerry Sandusky—Washington, Pennsylvania, Washington
* Frank Sheeran, Frank "The Irishman" Sheeran—Darby, Pennsylvania, Darby
* Sundance Kid—Mont Clare, Pennsylvania, Mont Clare
* Philip Testa—Philadelphia
* Salvatore Testa—Philadelphia

Educators

* Robert Balling, professor of geography, Arizona State University—Uniontown, Pennsylvania, Uniontown
* Algernon Sydney Biddle (1847–1891), lawyer and law professor at the University of Pennsylvania Law School
* Francis Bohlen (1868–1942), Algernon Sydney Biddle professor of law at the University of Pennsylvania Law School
* Derek Bok, 25th President of Harvard University—Bryn Mawr, Pennsylvania, Bryn Mawr
* Adda Burch (1869-1929), teacher-missionary at Concepción College (Concepción, Chile), Concepción College, Concepción, Chile
* Daniel Chamovitz, biologist, author of ''What a Plant Knows'', and President of Ben Gurion University of the Negev
* Harold W. Dodds, 15th President of Princeton University—Utica, Pennsylvania, Utica
* Steven Drizin, lawyer and law professor at the Northwestern University Pritzker School of Law
* Thomas Messinger Drown, fourth President of Lehigh University—Philadelphia
* C. Clement French, sixth president of Washington State University—Philadelphia
* Thomas F. George, chancellor and professor of chemistry and physics, University of Missouri–St. Louis—Philadelphia
* Leonard Hayflick, Professor of Anatomy, University of California, San Francisco—Philadelphia
* Susan Henking—Paoli, president of Shimer College
* John W. Heston, second president of Washington State University, Washington State; third president of South Dakota State University, South Dakota State; fourth president of Dakota State University, Dakota State—Bellefonte
* John Heuser, Professor of Biophysics, Washington University School of Medicine—Pittsburgh
* John Honnold (1915-2011), law professor at the University of Pennsylvania Law School
* Andrew H. Knoll, Andrew Knoll, Fisher Professor of Natural History and Professor of Earth and Planetary Sciences, Harvard University—West Reading, Pennsylvania, West Reading
* Noyes Leech (1921–2010), law professor at the University of Pennsylvania Law School
* Philip Morrison, Institute Professor Emeritus and professor of physics emeritus, Massachusetts Institute of Technology—Pittsburgh
* Julia Anna Orum (1843-1904), principal, Philadelphia School of Elocution
* Christopher Stuart Patterson (1842–1924), Dean of the University of Pennsylvania Law School
* Wendell Pritchett, Chancellor of Rutgers University–Camden, Interim Dean and Presidential Professor at the University of Pennsylvania Law School, and Provost of the University of Pennsylvania
* Curtis R. Reitz (born 1929), Algernon Sydney Biddle Professor of Law at the University of Pennsylvania Law School—Reading
* Louis B. Schwartz (1913-2003), law professor at the University of Pennsylvania Law School—Philadelphia
* David R. Soll, David Soll, biology professor, University of Iowa—Philadelphia
* Clyde Summers (1918-2010), labor lawyer and law professor at the University of Pennsylvania Law School—Germantown
* Bernard Wolfman (1924–2011), Dean of the University of Pennsylvania Law School and law professor—Philadelphia
* John Yoo, Professor of Law at the University of California, Berkeley—Philadelphia

Engineers and inventors

* James Henry Carpenter— Reading, Berks County, Pennsylvania, Berks County
* Edgar Cortright—Hastings, Pennsylvania, Hastings
* Sidney Darlington—Pittsburgh
* William C. Davis Jr.—Shinglehouse, Pennsylvania, Shinglehouse
* Henry Deringer—Easton, Pennsylvania, Johnstown
* Nance Dicciani—Philadelphia
* J. Presper Eckert—Philadelphia
* Jesse Fell—Wilkes-Barre
* Matthias N. Forney, Matthias Forney—Hanover, Pennsylvania, Hanover
* Benjamin Franklin—Boston, Massachusetts
* Daniel French (inventor), Daniel French—Brownsville, Pennsylvania, Brownsville and Philadelphia
* Robert Fulton—Little Britain Township, Lancaster County, Pennsylvania, Little Britain
* Frank Hastings Griffin—Chester
* Mary Hallock-Greenewalt—Philadelphia
* George H. Heilmeier—Philadelphia
* John Kanzius—Washington, Pennsylvania, Washington
* Samuel Kier—Conemaugh Township, Indiana County, Pennsylvania, Conemaugh Township
* Thomas Midgley Jr.—Beaver Falls, Pennsylvania, Beaver Falls
* William C. Pfefferle—Philadelphia
* Alan Pritsker—Philadelphia
* Henry Miller Shreve—Brownsville, Pennsylvania, Brownsville
* Jacob Snider—Philadelphia
* Frederick Winslow Taylor—Philadelphia
* William Hultz Walker—Pittsburgh
* Nathaniel Wyeth (inventor), Nathaniel Wyeth—Chadds Ford Township, Delaware County, Pennsylvania, Chadds Ford

Entrepreneurs, industrialists, and business executives

* John Aglialoro—Philadelphia
* Peter Angelos—Pittsburgh
* James Ford Bell—Philadelphia
* Manoj Bhargava—Philadelphia
* Steve Bisciotti—Philadelphia
* Mary Boone— Erie
* Amar Bose—Philadelphia
* Norman Braman— West Chester / Philadelphia
* Washington Atlee Burpee—Philadelphia
* Andrew Carnegie—Allegheny, Pennsylvania, Allegheny
* Joan Carter—Pittsburgh
* Kayla Collins— Reading
* Henry Pomeroy Davison—Troy, Pennsylvania, Troy
* Mark Donovan (American football), Mark Donovan—–Pittsburgh
* David Edgerton—–Lebanon, Pennsylvania, Lebanon
* Ella M. George—–Beaver Falls, Pennsylvania, Beaver Falls
* Alex Grass—– Scranton
* Clement Griscom—–Philadelphia
* Mahlon Haines—–York, Pennsylvania, York
* Joseph A. Hardy III, Joe Hardy—–Pittsburgh
* Maggie Hardy Knox—–Pittsburgh
* Richard Hayne—–Philadelphia
* Milton S. Hershey—–Derry Church (Hershey, Pennsylvania, Hershey)
* George Washington Hill—–Philadelphia
* Anna Morris Holstein—–Muncy, Pennsylvania, Muncy
* Alfred Hunt (steel magnate), Alfred Hunt—– Bethlehem, Brownsville, Pennsylvania, Brownsville and Philadelphia
* Lee Iacocca—Allentown, Pennsylvania, Allentown
* Bennett S. LeBow—Philadelphia
* Larry Lucchino—Pittsburgh
* David Montgomery (baseball), David Montgomery—Philadelphia
* Robert Nardelli—Old Forge, Lackawanna County, Pennsylvania, Old Forge
* Amedeo Obici—Wilkes-Barre
* Asa Packer—Jim Thorpe, Pennsylvania, Jim Thorpe (originally called Mauch Chunk)
* H.B. Reese—Derry Church (Hershey, Pennsylvania, Hershey)
* Frank E. Resnik, Frank Resnik—Unity Township, Westmoreland County, Pennsylvania, Unity Township
* Brian L. Roberts, Brian Roberts—Philadelphia
* Art Rooney—Coulterville
* Art Rooney II—Pittsburgh
* Richard Mellon Scaife—Pittsburgh
* Charles M. Schwab—Williamsburg, Pennsylvania, Williamsburg / Loretto, Pennsylvania, Loretto
* James Sinegal—Pittsburgh
* Jeffrey Skilling—Pittsburgh
* Jim Stamatis—Lehigh Valley
* John P. Surma, John Surma—Pittsburgh
* David Tepper—Pittsburgh
* Thomas Usher— Reading
* Jerry Wolman—Shenandoah, Pennsylvania, Shenandoah
* Joseph Wharton—Philadelphia
* Isaiah Vansant Williamson—Bensalem Township
* Samuel Van Leer— Reading

Film directors, producers, and screenwriters

* M. K. Asante—Philadelphia
* Joe Augustyn—Philadelphia
* Donald P. Bellisario—Cokeburg, Pennsylvania, Cokeburg
* Shane Black—Pittsburgh
* Richard Brooks—Philadelphia
* Chris Columbus (filmmaker), Chris Columbus—Spangler, Pennsylvania, Spangler
* Rusty Cundieff—Pittsburgh
* Lee Daniels—Philadelphia
* Brian De Palma—Philadelphia
* Caleb Deschanel—Philadelphia
* Neal Dodson—York
* David M. Evans—Wilkes-Barre, Pennsylvania, Wilkes-Barre
* Peter Farrelly—Phoenixville, Pennsylvania, Phoenixville
* Jonathan Frakes—Bellefonte, Pennsylvania, Bellefonte
* Antoine Fuqua—Pittsburgh
* Todd Gallagher—Greensburg, Pennsylvania, Greensburg
* Rowdy Herrington—Pittsburgh
* Marshall Herskovitz—Philadelphia
* Tigre Hill—Philadelphia
* Tamar Simon Hoffs— Johnstown
* Todd Holland—Meadville, Pennsylvania, Meadville
* David Hollander—Pittsburgh
* Kevin Hooks—Philadelphia
* David Howard (director), David Howard—Philadelphia
* Tamara Jenkins—Philadelphia
* Clark Johnson—Philadelphia
* Deborah Kaplan—Abington Township, Montgomery County, Pennsylvania, Abington
* Irvin Kershner—Philadelphia
* Randal Kleiser—Philadelphia
* Harold F. Kress—Pittsburgh
* Charles Leavitt—Pittsburgh
* Richard Lester—Philadelphia
* Herschell Gordon Lewis—Pittsburgh
* Steven Lisberger—Philadelphia
* Sidney Lumet—Philadelphia
* Abby Mann—Philadelphia / East Pittsburgh, Pennsylvania, East Pittsburgh
* Kathleen Marshall—Pittsburgh
* Elaine May—Philadelphia
* Melanie Mayron—Philadelphia
* Adam McKay—Malvern, Pennsylvania, Malvern
* Nancy Meyers—Philadelphia
* Jason Miller (playwright), Jason Miller— Scranton
* David Mirkin—Philadelphia
* Clifford Odets—Philadelphia
* Eric Red—Pittsburgh
*James Rolfe—Philadelphia
* Richard Rossi—Pittsburgh
* Alvin Sargent—Philadelphia
* Tom Savini—Pittsburgh
* Edwin Sherin— Harrisburg
* M. Night Shyamalan—Philadelphia
* Jerry Stahl—Pittsburgh
* Joseph Strick—Braddock, Pennsylvania, Braddock
* Andrew Kevin Walker— Altoona / Mechanicsburg, Pennsylvania, Mechanicsburg
* Paul Wendkos—Philadelphia
* Sam Wood—Philadelphia
* Bud Yorkin—Washington, Pennsylvania, Washington

Musicians

; A–G

* Christina Aguilera—Pittsburgh
* Josh Balz ex keyboardist, Motionless in White
* Marian Anderson—Philadelphia
* Mark Andes—Philadelphia
* Frankie Avalon—Philadelphia
* Samuel Barber—West Chester
* Gabby Barrett--Pittsburgh
* Franny Beecher— Norristown
* George Benson—Pittsburgh
* Les Brown (bandleader), Les Brown—Lykens
* Benjamin Burnley—Wilkes Barre
* Bilal (American singer), Bilal—Philadelphia
* Joe Bonsall—Philadelphia
* Glenn Branca— Harrisburg
* Solomon Burke—Philadelphia
* Vanessa Carlton—Milford, Pennsylvania, Milford
* Sabrina Carpenter—Quakertown, Pennsylvania, Quakertown
* Cassidy (rapper), Cassidy—Philadelphia
* Danny Cedrone—Philadelphia
* Chubby Checker—Philadelphia
* Lou Christie—Moon Township, Pennsylvania, Moon Township
* Todd Tamanend Clark—Greensboro, Pennsylvania, Greensboro
* Stanley Clarke—Philadelphia
* Vinnie Colaiuta—Brownsville, Pennsylvania, Brownsville
* John Coltrane—Philadelphia
* Perry Como—Canonsburg, Pennsylvania, Canonsburg
* Joey Covington—Johnstown
* Crobot (rock band)—Pottsville, Pennsylvania, Pottsville
* Jim Croce—South Philadelphia, Pennsylvania, South Philadelphia
* Patrick Dahlheimer—York, Pennsylvania, York
* Bobby Dall—Mechanicsburg, Pennsylvania, Mechanicsburg
* Lacy J. Dalton—Bloomsburg, Pennsylvania, Bloomsburg
* Daya (singer), Daya—Pittsburgh
* Jimmy Dorsey—Shenandoah, Pennsylvania, Shenandoah
* Tommy Dorsey—Shenandoah, Pennsylvania, Shenandoah
* Jimmy DeGrasso— Bethlehem
* Esteban (musician), Esteban—Pittsburgh
* Kevin Eubanks—Philadelphia
* Jackie Evancho—Pittsburgh
* Eve (entertainer), Eve—Philadelphia
* Renée Fleming—Indiana, Pennsylvania, Indiana
* Stephen Foster—Pittsburgh
* James Moyer Franks—Trappe, Pennsylvania, Trappe
* Freeway (rapper), Freeway—Philadelphia
* James Allen Gähres— Harrisburg
* Joe Genaro, The Dead Milkmen—Wagontown, Pennsylvania, Wagontown
* Stan Getz—Philadelphia
* Adam Goldstein, Adam "DJ AM" Goldstein—Philadelphia
* Chad Gracey—York, Pennsylvania, York
* Johnny Grande—Philadelphia
* Anthony Green (musician), Anthony Green—Doylestown, Pennsylvania, Doylestown
* Justin Guarini—Doylestown, Pennsylvania, Doylestown

; H–M

* Hair Rocket—Philadelphia indie rock band
* Lzzy Hale—Red Lion, York County, Pennsylvania, Red Lion
* Daryl Hall—Pottstown, Pennsylvania, Pottstown
* Mary Hallock-Greenewalt—Philadelphia
* Dan Hartman— Harrisburg
* Phyllis Hyman—Pittsburgh
* Donnie Iris—Ellwood City, Pennsylvania, Ellwood City
* Keith Jarrett—Allentown, Pennsylvania, Allentown
* DJ Jazzy Jeff—Philadelphia
* Joan Jett—Philadelphia
* Allan Jones (actor), Allan Jones—Old Forge, Lackawanna County, Pennsylvania, Old Forge
* Wiz Khalifa—Pittsburgh
* Jason Karaban— Norristown
* Tom Keifer—Springfield
* Chris Kirkpatrick ('N Sync)—Clarion, Pennsylvania, Clarion
* Richie Kotzen—Reading
* Ed Kowalczyk—York, Pennsylvania, York
* Kurupt—Philadelphia
* Jeff LaBar—Darby, Pennsylvania, Darby
* Patti LaBelle—Philadelphia, Pennsylvania, Philadelphia
* Mario Lanza—Philadelphia
* Rodney Linderman, The Dead Milkmen—Wagontown, Pennsylvania, Wagontown
* Lil Peep (Gustav Elijah Åhr)—Allentown, Pennsylvania, Allentown
* Lil Skies—Waynesboro, Pennsylvania, Waynesboro
* Lil Uzi Vert—Philadelphia
* Lisa Lopes—Philadelphia
* Kellee Maize—Pittsburgh
* Henry Mancini—Aliquippa, Pennsylvania, Aliquippa
* Fred Mascherino— Philadelphia, Coatesville, Pennsylvania, Coatesville
* Al Martino—Philadelphia
* Pat Martino—Philadelphia
* Billy May—Pittsburgh
* Dan McKeown—Philadelphia
* Meek Mill—Philadelphia
* Mac Miller—Pittsburgh
* Garnet Mimms—Philadelphia
* Bret Michaels—Butler
* Mirah—Philadelphia
* Irene Molloy—Doylestown, Pennsylvania, Doylestown
* Patrick Monahan— Erie
* Chris Motionless— Scranton
* Musiq Soulchild—Philadelphia

; N–Z

* Jaco Pastorius— Norristown
* Billy Paul—Philadelphia
* Teddy Pendergrass—Philadelphia
* Christina Perri—Bensalem Township, Bucks County, Pennsylvania, Bensalem
* Pink (singer), Pink—Doylestown, Pennsylvania, Doylestown
* Jack Pleis—Philadelphia
* Questlove—Philadelphia
* Sun Ra—Philadelphia
* Trent Reznor—Mercer, Pennsylvania, Mercer
* PnB Rock—Philadelphia
* Rikki Rockett—Mechanicsburg, Pennsylvania, Mechanicsburg
* Asher Roth—Morrisville, Bucks County, Pennsylvania, Morrisville
* Todd Rundgren—Upper Darby, Pennsylvania, Upper Darby
* Bobby Rydell—Philadelphia
* Ira D. Sankey—New Castle, Pennsylvania, New Castle
* Santigold, Santogold—Philadelphia
* Schooly D—Philadelphia
* Jill Scott (singer), Jill Scott—Philadelphia
* Shanice—Pittsburgh
* Beanie Sigel—Philadelphia
* Langhorne Slim (Sean Scolnick (Langhorne Slim)—Langhorne, Pennsylvania, Langhorne
* Will Smith—Philadelphia
* Ivy Sole—Philadelphia
* Jack Stauber—Erie
* Leopold Stokowski—Philadelphia
* Taylor Swift— Reading
* Tammi Terrell—Philadelphia
* McCoy Tyner—Philadelphia
* Bobby Vinton—Canonsburg, Pennsylvania, Canonsburg
* Chris Vrenna— Erie
* John Walker (organist), John Walker— Johnstown
* Dean Ween—New Hope
* Gene Ween—Philadelphia
* M. E. Willson—Penfield
* Denison Witmer, Lancaster
* Michael J. Woodard—Philadelphia
* Syreeta Wright—Pittsburgh

Natural scientists and physicians

* Edward Goodrich Acheson, Edward Acheson—Washington, Pennsylvania, Washington
* Anurag Agrawal (ecologist), Anurag Agrawal—Allentown, Pennsylvania, Allentown
* Christian B. Anfinsen, Christian Anfinsen—Monessen, Pennsylvania, Monessen
* Alexander Dallas Bache—Philadelphia
* Albert C. Barnes, Albert Barnes—Philadelphia
* Michael Behe— Altoona
* Elmer Keiser Bolton, Elmer Bolton—Frankford, Philadelphia, Frankford
* James Bond (ornithologist), James Bond—Philadelphia
* James Curtis Booth, James Booth—Philadelphia
* Herbert Boyer—Derry, Pennsylvania, Derry
* Robert Stanley Breed, Robert Breed—Brooklyn Township, Susquehanna County, Pennsylvania, Brooklyn Township
* Michael Stuart Brown—Wyncote, Pennsylvania, Wyncote
* Sean M. Carroll—Philadelphia
* Rachel Carson— Springdale
* Daniel Chamovitz—Aliquippa
* Britton Chance—Wilkes-Barre, Pennsylvania, Wilkes-Barre
* Ralph J. Cicerone, Ralph Cicerone—New Castle, Pennsylvania, New Castle
* Edward Drinker Cope, Edward Cope—Philadelphia
* James F. Crow—Phoenixville, Pennsylvania, Phoenixville
* George Delahunty—Upper Darby
* John Thompson Dorrance, John Dorrance—Bristol, Pennsylvania, Bristol
* Alice Catherine Evans, Alice Evans—Neath
* John Fries Frazer, John Frazer—Philadelphia
* Frederick Augustus Genth, Frederick Genth—Philadelphia
* Frederick Grinnell (biologist), Frederick Grinnell—Philadelphia
* Robert Hare (chemist), Robert Hare—Philadelphia
* William Draper Harkins, William Harkins—Titusville, Pennsylvania, Titusville
* Philip Showalter Hench, Philip Hench—Pittsburgh
* Berwind P. Kaufmann, Berwind Kaufmann—Philadelphia
* Charles David Keeling, Charles Keeling— Scranton
* John Kopchick—Punxsutawney, Pennsylvania, Punxsutawney
* Stephanie Kwolek—New Kensington, Pennsylvania, New Kensington
* Edward B. Lewis, Edward Lewis—Wilkes-Barre
* Stephen J. Lippard, Stephen Lippard—Pittsburgh
* William Madia—Wilkinsburg, Pennsylvania, Wilkinsburg
* Daniel Mazia— Scranton
* Samuel George Morton—Philadelphia
* Jack Myers (biologist), Jack Myers—Damascus Township, Wayne County, Pennsylvania, Damascus Township
* Charles G. Overberger, Charles Overberger—Barnesboro, Pennsylvania, Barnesboro
* Mary Engle Pennington, Mary Pennington—Philadelphia
* Anna M. Longshore Potts–Attleboro (now Langhorne, Pennsylvania, Langhorne)
* George C. Prendergast, George Prendergast—Philadelphia
* John Quackenbush—Kingston, Pennsylvania, Kingston
*David L. Reich—Philadelphia
* Theodore William Richards, Theodore Richards—Germantown, Philadelphia, Germantown
* Charles M. Rick, Charles Rick— Reading
* Anita Roberts—Pittsburgh
* James Blythe Rogers, James Rogers—Philadelphia
* William Barton Rogers, William Rogers—Philadelphia
* Henry Augustus Rowland—Honesdale, Pennsylvania, Honesdale
* Beth Shapiro—Allentown, Pennsylvania, Allentown
* Alex Shigo—Duquesne, Pennsylvania, Duquesne
* Lester Shubin—Philadelphia
* Neil Shubin—Philadelphia
* Daniel Simberloff—Wilson, Pennsylvania, Wilson
* Edgar Fahs Smith, Edgar Smith—York, Pennsylvania, York
* Howard Martin Temin, Howard Temin—Philadelphia
* Claude Alvin Villee Jr.— Lancaster
* Bernardhus Van Leer (1687–1790), one of the first doctors in New York
* William Hultz Walker, William Walker—Pittsburgh
* Michael Welner—Pittsburgh
* Caspar Wistar (physician), Caspar Wistar—Philadelphia
* Rake Yohn— West Chester
* Roger Arliner Young, Roger Young—Burgettstown, Pennsylvania, Burgettstown

Politics, government, and military

; A–M

* Claude Allen, assistant to the President for domestic policy under George W. Bush—Philadelphia
* Jason Altmire, author and U.S. Representative—Lower Burrell
* Henry H. Arnold, Henry "Hap" Arnold, U.S. Army and U.S. Air Force General—Gladwyne, Pennsylvania, Gladwyne
* John C. Bell Jr., 33rd Governor of Pennsylvania—Philadelphia
* Joe Biden, current President of the United States, 47th Vice President of the United States (2009–2017), longtime U.S. Senator from Delaware (1973–2009)—Scranton
* Robert Bork, Solicitor General, Attorney General, Judge of the D.C. Circuit Court of Appeals, Supreme Court nominee—Pittsburgh
* John Boyd (military strategist), John Boyd, United States Air Force, USAF fighter pilot and The Pentagon, Pentagon consultant, developer of the OODA loop— Erie
* Martin Grove Brumbaugh, 26th Governor of Pennsylvania—Huntingdon County, Pennsylvania, Huntingdon County
* James Buchanan, 15th President of the United States—Cove Gap, Pennsylvania, Cove Gap
* Smedley Butler, U.S. Marine Corps General— West Chester
* Frank Carlucci, U.S. Secretary of Defense under Ronald Reagan—Scranton
* Samuel Carpenter, first Treasurer 1704, Deputy Governor to William Penn—Philadelphia
* Ashton Carter, U.S. Secretary of Defense under Barack Obama—Philadelphia
* Bob Casey Jr., US Senator, son of former Governor—Scranton
* Robert P. Casey, 42nd Governor of Pennsylvania—Scranton
* Benjamin Chew, Chief Justice of Supreme Court of Pennsylvania, state Attorney General—Philadelphia
* Joseph Clancy (Secret Service), Joseph Clancy, Director of Secret Service under Barack Obama—Philadelphia
* Mark B. Cohen, Democratic chairman, Human Services Committee, Pennsylvania House of Representatives
* William Thaddeus Coleman Jr., William Coleman, U.S. Secretary of Transportation under Gerald Ford—Philadelphia
* Tom Corbett, 46th Governor of Pennsylvania—Philadelphia
* George M. Dallas, 11th Vice President of the United States—Philadelphia
* James J. Davis, U.S. Secretary of Labor, U.S. Senator—Pittsburgh
* James H. Duff, U.S. Senator and 34th Governor—Carnegie, Pennsylvania, Carnegie
* R. Budd Dwyer, treasurer, State Senator and Representative— Harrisburg
* George Howard Earle III, 30th Governor of Pennsylvania—Montgomery County, Pennsylvania, Montgomery County
* Peter Feaver, National Security Council member for Presidency of Bill Clinton, Clinton and Presidency of George W. Bush, Bush administrations— Bethlehem
* Bob Filner, Mayor of San Diego—Pittsburgh
* John Stuchell Fisher, 29th Governor of Pennsylvania—South Mahoning Township, Pennsylvania, South Mahoning Twp.
* Benjamin Franklin, scientist, diplomat, teacher, and founding father of the United States— Philadelphia
* Frank Gaffney, Deputy Assistant Secretary of Defense under Ronald Reagan—Pittsburgh
* Newt Gingrich, Speaker of the U.S. House of Representatives—Harrisburg
* Alexander Haig, Secretary of State, White House Chief of Staff, NATO Supreme Commander—Philadelphia
* Winfield Scott Hancock, Union Civil War commander—Montgomeryville, Pennsylvania, Montgomeryville
* Orrin Hatch, Republican senator from Utah—Pittsburgh
* Michael Hayden (general), Michael Hayden, Director of CIA under George W. Bush—Pittsburgh
* William G. Hundley, criminal defense attorney—Pittsburgh
* Harold L. Ickes, Secretary of Interior under Franklin D. Roosevelt— Altoona
* Arthur James (politician), Arthur James, 31st Governor of Pennsylvania—Plymouth, Pennsylvania, Plymouth
* Michael Johns (policy analyst), Michael Johns, U.S. Presidential speechwriter—Emmaus, Pennsylvania, Emmaus
* George Joulwan, U.S. Army General—Pottsville, Pennsylvania, Pottsville
* John Kasich, Congressman from Ohio (1983–2001), 69th List of Governors of Ohio, Governor of Ohio, presidential candidate in 2016 United States presidential election, 2016 and 2000 United States presidential election, 2000—Pittsburgh
* Donald Kohn, Vice Chairman of Federal Reserve—Philadelphia
* Alf Landon, Governor of Kansas and presidential candidate—West Middlesex, Pennsylvania, West Middlesex
* Andrew L. Lewis Jr., Andrew Lewis, Secretary of Transportation under Ronald Reagan—Philadelphia
* Richard Marcinko, Navy Seal, commanded Seal Team Six—Lansford, Pennsylvania, Lansford
* George Marshall, Secretary of Defense under Harry S. Truman—Uniontown
* Edward Martin (Pennsylvania politician), Edward Martin, U.S. Senator and 32nd Governor of Pennsylvania—Ten Mile, Pennsylvania, Ten Mile
* Betsy McCaughey, Lieutenant Governor of state of New York—Pittsburgh
* John J. McCloy, Assistant Secretary of War during World War II—Philadelphia
* H. R. McMaster, National Security Advisor, U.S. Army Lt. General—Philadelphia
* Royal Meeker, advisor to President Woodrow Wilson—Quaker Lake
* Thomas Mifflin, first Governor of Pennsylvania—Philadelphia

; N–Z

* Janet Napolitano, U.S. Secretary of Homeland Security—Pittsburgh
* Benjamin Netanyahu, Prime Minister of Israel—Cheltenham Township, Pennsylvania, Cheltenham Township
* Clarence Charles Newcomer (1923–2005), US District Judge of the United States District Court for the Eastern District of Pennsylvania
* John Olver, U.S. Representative from Massachusetts—Honesdale, Pennsylvania, Honesdale
* Alexander Mitchell Palmer, U.S. Attorney General, director of controversial Palmer Raids—White Haven, Pennsylvania, White Haven
* Rand Paul, U.S. Senator (R-KY)—Pittsburgh
* Ron Paul, U.S. House of Representatives (R-TX)—Pittsburgh
* Samuel W. Pennypacker, 23rd Governor of Pennsylvania—Phoenixville, Pennsylvania, Phoenixville
* Robert Reich, Secretary of Labor under Bill Clinton— Scranton
* Ed Rendell, 45th Governor of Pennsylvania—Philadelphia
* George S. Rentz, World War II Navy Chaplain and Navy Cross awardee—Lebanon, Pennsylvania, Lebanon
* Tom Ridge, Governor, first Secretary of Homeland Security—Munhall, Pennsylvania, Munhall
* Alice Rivlin, Director of the Office of Management and Budget under Bill Clinton, Vice Chair of the Federal Reserve System—Philadelphia
* John Roll, federal judge slain in 2011 Tucson shooting in Arizona—Pittsburgh
* Dan Rooney, U.S. United States Ambassador to Ireland, Ambassador to Ireland—Pittsburgh
* Betsy Ross, credited maker of original American flag—Philadelphia
* Bayard Rustin, activist, organizer of social movements for civil rights, socialism, nonviolence, and gay rights— West Chester
* Richard Schweiker, Congressman, Senator, and United States Secretary of Health and Human Services, Secretary of Health and Human Services under Ronald Reagan— Norristown
* Joe Sestak, Navy Admiral and Congressman—Secane, Pennsylvania, Secane
* Raymond P. Shafer, Governor of Pennsylvania—New Castle, Pennsylvania, New Castle
* Jeanne Shaheen, U.S. Senator and Governor of New Hampshire—Selinsgrove, Pennsylvania, Selinsgrove
* Don Sherwood (politician), Don Sherwood, U.S. Representative (R-PA)—Tunkhannock, Pennsylvania, Tunkhannock
* D. Brooks Smith, federal judge on United States Court of Appeals for the Third Circuit, Court of Appeals— Altoona
* Carl Andrew Spaatz, WWII general and first Chief of Staff of the U.S. Air Force— Boyertown
* Arlen Specter, U.S. Senator (R-PA)—Philadelphia
* William Cameron Sproul, 27th Governor of Pennsylvania—Lancaster County, Pennsylvania, Lancaster County
* Thaddeus Stevens, Constitutional activist— Gettysburg
* William A. Stone, 22nd Governor of Pennsylvania—Wellsboro, Pennsylvania, Wellsboro
* Edwin Sydney Stuart, 24th Governor of Pennsylvania—Philadelphia
* Lawrence Summers, Director of United States National Economic Council, National Economic Council under Barack Obama—Penn Valley, Pennsylvania, Penn Valley
*Gregory Tony (born 1978), Broward County Sheriff's Office, Sheriff of Broward County, Florida-Philadelphia
* Charlemagne Tower, lawyer, mining magnate and landowner—Pottsville, Pennsylvania, Pottsville
* Samuel Van Leer, Pennsylvania Irons works owner and a United States Army officer—Chester County, Pennsylvania, Chester County
* Tom Vilsack, U.S. Secretary of Agriculture, Governor of Iowa—Pittsburgh
* Alfred L. Wilson, U.S. Army Medal of Honor recipient—Fairchance, Pennsylvania, Fairchance
* Curtin Winsor Jr., U.S. United States Ambassador to Costa Rica, Ambassador to Costa Rica under Ronald Reagan—Philadelphia
* Richard Winters, 101st Airborne, 506th E Company, World War II— Lancaster

Radio and television

* Jodi Applegate, broadcast journalist—Moon Township, Pennsylvania, Moon Township
* Michael Barkann, radio talk show host, television host—Newtown Square, Pennsylvania, Newtown Square
* Chuck Barris, television host and producer—Philadelphia
* John Batchelor, radio talk show host—Bryn Mawr, Pennsylvania, Bryn Mawr / Lower Merion Township, Montgomery County, Pennsylvania, Lower Merion Township
* Jaiden Nichols, youtuber— Pittsburgh
* Ron Bennington, radio personality and comedian, ''Ron and Fez, The Ron and Fez Show''—Philadelphia
* Jerry Blavat, disc jockey—Philadelphia
* Neal Boortz, libertarian Radio personality, radio talk show host—Bryn Mawr, Pennsylvania, Bryn Mawr
* Michael Buffer, ring announcer known for his trademarked catchphrase, "Let's get ready to rumble!"—Philadelphia / Roslyn, Pennsylvania, Roslyn
* Steve Burns, original host of the kids' show ''Blue's Clues''— Boyertown
* Steve Capus, former president of NBC News—Bryn Mawr, Pennsylvania, Bryn Mawr
* Todd Christensen, sports broadcaster for the MountainWest Sports Network—Bellefonte, Pennsylvania, Bellefonte
* Myron Cope, former Pittsburgh Steelers radio personality—Pittsburgh
* Regis Cordic, former radio personality; actor in ''Columbo'', ''Gunsmoke''—Pittsburgh
* Jim Cramer, television personality—Wyndmoor, Pennsylvania, Wyndmoor
* Bill Cullen, television personality—Pittsburgh
* Sharon Epperson, correspondent for CNBC—Pittsburgh
* Howard Eskin, Philadelphia-based sports radio personality—Philadelphia
* Debra Fox, television anchor—Pittsburgh
* Pauline Frederick (journalist), Pauline Frederick, newspaper, TV, and radio journalist—Gallitzin, Pennsylvania, Gallitzin
* Alan Freed, radio disc jockey who coined the term "Rock and Roll"—Windber, Pennsylvania, Windber
* Courtney Friel, entertainment reporter for Fox News— Norristown
* Louis Glackens, illustrator—Philadelphia
* Jon & Kate Plus 8, Jon & Kate Gosselin, reality TV personalities (Jon & Kate Plus 8), family of 10 with sextuplets and twins—Wyomissing, Pennsylvania, Wyomissing
* Andy Gresh, talk show host, television host, color commentator—Brownsville, Pennsylvania, Brownsville
* Marc Lamont Hill, BET News correspondent, CNN political commentator—Philadelphia
* Marilyn Horne, opera singer—Bradford, Pennsylvania, Bradford
* Abby Huntsman, co-host of ''Fox & Friends Weekend''—Philadelphia
* Suzy Kolber, television sportscaster—Upper Dublin Township, Pennsylvania, Upper Dublin Township
* Andrea Kremer, television sportscaster—Philadelphia
* Carson Kressley, TV personality, ''Queer Eye (2003 TV series), Queer Eye'', ''How to Look Good Naked''—Allentown, Pennsylvania, Allentown
* Mark Levin, radio talk show host, conservatism in the United States, conservative political commentator—Cheltenham Township, Montgomery County, Pennsylvania, Cheltenham Township
* Joe Lunardi, college basketball analyst for ESPN—Philadelphia
* Meredith Marakovits, New York Yankees clubhouse reporter for the YES Network—Walnutport, Pennsylvania, Walnutport
* Bam Margera, reality television personality and skateboarder—West Chester
* Chris Matthews, political commentator, MSNBC's ''Hardball with Chris Matthews, Hardball''—Philadelphia
* Billy Mays, TV direct-response marketing, direct-response advertising salesman and star of Discovery Channel, Discovery Channel's ''Pitchmen''—McKees Rocks, Pennsylvania, McKees Rocks
* Michael Medved, talk radio host, conservatism in the United States, conservative commentator, film critic—Philadelphia
* Jeanne Moos, broadcast journalist for CNN—Pittsburgh
* Clayton Morris, co-host of ''Fox & Friends Weekend''—Spring Township, Berks County, Pennsylvania, Spring Township
* Charlie O'Donnell, radio/TV announcer, primarily on game shows—Philadelphia
* Beth Ostrosky, model, judge on American Broadcasting Company, ABC's ''True Beauty (American TV series), True Beauty'' and host of G4 (U.S. TV channel), G4's ''Filter (TV series), Filter''—Pittsburgh
* Victoria Pedretti, actress in The Haunting of Hill House (TV series), The Haunting series and You (TV series), You — Fairless Hills
* Billy Porter (entertainer), Billy Porter, actor in ''Pose (TV series), Pose'' and Broadway performer in ''Kinky Boots (musical), Kinky Boots''— Pittsburgh
* Jack Posobiec, correspondent for One America News Network— Norristown
* Fred Rogers, television personality, ''Mr. Rogers' Neighborhood''—Latrobe, Pennsylvania, Latrobe
* Norman Rose, radio announcer (NBC, NBC's ''Dimension X (radio program), Dimension X'' and ''CBS Radio Mystery Theater'')—Philadelphia
* Ryan Sampson, radio personality, The Morning Mash Up Sirius XM Hits 1—Titusville, Pennsylvania, Titusville
* Ray Scott (sportscaster), Ray Scott, sportscaster for the Green Bay Packers— Johnstown
* Steve Scully, host of C-SPAN's ''Washington Journal''— Erie
* Paul Shannon, host of Adventuretime, WTAE Channel 4—Pennsylvania, Crafton
* Dick Stockton, sportscaster for Fox Sports (USA), Fox Sports and Turner Sports—Philadelphia
* Andrea Tantaros, political analyst and commentator on Fox News and Fox Business Network—Allentown, Pennsylvania, Allentown
* Jake Tapper, anchor for CNN, ''The Lead with Jake Tapper'', ''State of the Union with Jake Tapper, State of the Union''—Philadelphia
* Jesse Watters, commentator for Fox News, host of ''Watters' World''—Philadelphia
* Kristen Welker, broadcast journalist for NBC News—Philadelphia
* Maddie Ziegler, actor, featured dancer on ''Dance Moms''— Murrysville

Religion

* Tony Campolo—Philadelphia
* Fanny DuBois Chase—Great Bend, Pennsylvania, Great Bend
* Walter Ciszek—Shenandoah, Pennsylvania, Shenandoah
* Harvey Cox—Malvern, Pennsylvania, Malvern
* Mary Helen Peck Crane–Wilkes-Barre, Pennsylvania, Wilkes-Barre
* Amy Eilberg—Philadelphia
* Demetrius Augustine Gallitzin, Prince Demetrius Gallitzin—Cambria County, Pennsylvania, Cambria County
* Washington Gladden—Pottsgrove, Pennsylvania, Pottsgrove
* Lillian Resler Harford–Mount Pleasant, Pennsylvania, Mount Pleasant
* Barry W. Lynn, Barry Lynn— Harrisburg / Bethlehem
* Jeanette DuBois Meech–Frankford, Philadelphia, Frankford
* Bruce M. Metzger, Bruce Metzger—Middletown, Dauphin County, Pennsylvania, Middletown
* Mary A. Miller–Allegheny, Pennsylvania, Allegheny
* David Miscavige— Bucks County
* Joseph Murgas—Wilkes Barre, Pennsylvania, Wilkes Barre / Slovakia
* Michael Novak— Johnstown
* Charles Taze Russell— Pittsburgh
* Jeremiah WRev. Jeremiah Wright—Philadelphia

Social scientists and academics

* Russell L. Ackoff—Philadelphia
* Clayton Alderfer—Sellersville, Pennsylvania, Sellersville
* Gary Becker—Pottsville, Pennsylvania, Pottsville
* Julian Bond—Philadelphia
* Edwin Boring—Philadelphia
* Leonard Burman—Philadelphia
* Paul Cameron—Pittsburgh
* Henry Charles Carey—Philadelphia
* Leonard Carmichael—Philadelphia
* James McKeen Cattell— Easton
* Noam Chomsky—Philadelphia
* Randolph Cohen—Philadelphia
* Leda Cosmides—Philadelphia
* Robert Costanza—Pittsburgh
* Albert Ellis—Pittsburgh
* Joshua Fishman—Philadelphia
* W. Nelson Francis—Philadelphia
* Harry Frankfurt—Langhorne, Pennsylvania, Langhorne
* Walter Jackson Freeman II, Walter Freeman—Philadelphia
* Howard Gardner— Scranton
* Henry George—Philadelphia
* Douglas Holtz-Eakin—Pittsburgh
* Noel Ignatiev—Philadelphia
* Jane Jacobs— Scranton
* Jacob Robert Kantor, Jacob Kantor— Harrisburg
* William Williams Keen, William Keen—Philadelphia
* Sally Kohn—Allentown, Pennsylvania, Allentown
* Donald N. Levine—New Castle, Pennsylvania, New Castle
* Edward B. Lewis—Wilkes-Barre
* Esther J. Trimble Lippincott–Kimberton, Pennsylvania, Kimberton
* John McWhorter—Philadelphia
* Margaret Mead—Philadelphia / Doylestown, Pennsylvania, Doylestown
* Robert K. Merton—Philadelphia
* Albert Jay Nock— Scranton
* Hilary Putnam—Philadelphia
* Robert Reich— Scranton
* David Riesman—Philadelphia
* Clinton Rossiter—Philadelphia
* Michael Rubin—Philadelphia
* B. F. Skinner—Susquehanna Depot, Pennsylvania, Susquehanna
* Jude Wanniski—Pottsville, Pennsylvania, Pottsville
* Walter E. Williams, Walter Williams—Philadelphia
* Alan Wolfe—Philadelphia
* Michael Yates (economist), Michael Yates—Pittsburgh
* Robert Yerkes—Breadysville, Bucks County

See also

* List of people from Erie, Pennsylvania
*List of people from the Lehigh Valley
* List of people from Lancaster County, Pennsylvania
* List of people from Philadelphia
* List of people from the Pittsburgh metropolitan area
* List of people from York, Pennsylvania

Notes

References

External links

"Famous People from the Lehigh Valley
" ''The Morning Call'', August 18, 2006

{{authority control

Lists of people from Pennsylvania,