List Of Legionnaires' Disease Outbreaks
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Legionnaires' disease Legionnaires' disease is a form of atypical pneumonia caused by any species of ''Legionella'' bacteria, quite often ''Legionella pneumophila''. Signs and symptoms include cough, shortness of breath, high fever, myalgia, muscle pains, and headach ...
outbreaks; Legionnaire's is a potentially fatal
infectious disease An infection is the invasion of tissue (biology), tissues by pathogens, their multiplication, and the reaction of host (biology), host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmis ...
caused by
gram negative Gram-negative bacteria are bacteria that, unlike gram-positive bacteria, do not retain the crystal violet stain used in the Gram staining method of bacterial differentiation. Their defining characteristic is that their cell envelope consists of ...
, aerobic
bacteria Bacteria (; : bacterium) are ubiquitous, mostly free-living organisms often consisting of one Cell (biology), biological cell. They constitute a large domain (biology), domain of Prokaryote, prokaryotic microorganisms. Typically a few micr ...
belonging to the
genus Genus (; : genera ) is a taxonomic rank above species and below family (taxonomy), family as used in the biological classification of extant taxon, living and fossil organisms as well as Virus classification#ICTV classification, viruses. In bino ...
''
Legionella ''Legionella'' is a genus of gram-negative bacteria, gram-negative bacteria that can be seen using a silver stain or grown in a special media that contains cysteine, an amino acid. It is known to cause legionellosis (all illnesses caused by ''Legi ...
''. The first reported outbreak was in Philadelphia, Pennsylvania in 1976 during a Legionnaires Convention at the
Bellevue-Stratford Hotel The Bellevue-Stratford Hotel is a landmark building at 200 S. Broad Street (Philadelphia), Broad Street at the corner of Walnut Street (Philadelphia), Walnut Street in Center City, Philadelphia, Center City Philadelphia, Pennsylvania. Construct ...
. An outbreak is defined as two or more cases where the onset of illness is closely linked in time (weeks rather than months) ''and'' in space, where there is suspicion of, or evidence of, a common source of infection, with or without microbiological support (''i.e.'' common spatial location of cases from travel history).


Worldwide listings by year


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Governmental controls to prevent outbreaks


Regulations and ordinances

The guidance issued by the UK government's Health and Safety Executive (HSE) now recommends that microbiological monitoring for wet cooling systems, using a dipslide, should be performed weekly. The guidance now also recommends that routine testing for legionella bacteria in wet cooling systems be carried out at least quarterly, and more frequently when a system is being commissioned, or if the bacteria have been identified on a previous occasion. Further non-statutory UK guidance from the Water Regulations Advisory Scheme now exists for pre-heating of water in applications such as
solar water heating Solar water heating (SWH) is water heating, heating water by sunlight, using a solar thermal collector. A variety of configurations are available at varying cost to provide solutions in different climates and latitudes. SWHs are widely used for ...
systems. The City of
Garland, Texas Garland is a city in the U.S. state of Texas, located within Dallas County, Texas, Dallas County with portions extending into Collin County, Texas, Collin and Rockwall County, Texas, Rockwall counties. It is located northeast of Dallas and is a ...
,
United States The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic of 50 U.S. state, states and a federal capital district, Washington, D.C. The 48 ...
requires yearly testing for legionella bacteria at cooling towers at apartment buildings.
Malta Malta, officially the Republic of Malta, is an island country in Southern Europe located in the Mediterranean Sea, between Sicily and North Africa. It consists of an archipelago south of Italy, east of Tunisia, and north of Libya. The two ...
requires twice yearly testing for ''Legionella'' bacteria at cooling towers and water fountains.
Malta Malta, officially the Republic of Malta, is an island country in Southern Europe located in the Mediterranean Sea, between Sicily and North Africa. It consists of an archipelago south of Italy, east of Tunisia, and north of Libya. The two ...
prohibits the installation of new cooling towers and evaporative condensers at health care facilities and schools. The Texas Department of State Health Services has provided guidelines for hospitals to detect and prevent the spread of
nosocomial infection A hospital-acquired infection, also known as a nosocomial infection (from the Greek , meaning "hospital"), is an infection that is acquired in a hospital or other healthcare facility. To emphasize both hospital and nonhospital settings, it is s ...
due to legionella. The European Working Group for Legionella Infections (EWGLI) was established in 1986 within the
European Union The European Union (EU) is a supranational union, supranational political union, political and economic union of Member state of the European Union, member states that are Geography of the European Union, located primarily in Europe. The u ...
framework to share knowledge and experience about potential sources of ''Legionella'' and their control. This group has published guidelines about the actions to be taken to limit the number of colony forming units (i.e., the "aerobic count") of micro-organisms per mL at 30 °C (minimum 48 hours incubation): Almost all natural water sources contain ''Legionella'' and their presence should not be taken as an indication of a problem. The tabled figures are for total aerobic plate count, cfu/ml at 30 °C (minimum 48 hours incubation) with colony count determined by the pour plate method according to ISO 6222(21) or spread plate method on yeast extract agar. Legionella isolation can be conducted using the method developed by the US Center for Disease Control using buffered charcoal yeast extract agar with antibiotics. Copper-Silver ionization is an effective industrial control and prevention process to eradicate ''Legionella'' in potable water distribution systems and cooling towers found in health facilities, hotels, nursing homes and most large buildings. In 2003, ionization became the first such hospital disinfection process to have fulfilled a proposed four-step modality evaluation; by then it had been adopted by over 100 hospitals. Additional studies indicate ionization is superior to thermal eradication. A 2011 study by Lin, Stout and Yu found Copper-Silver ionization to be the only Legionella control technology which has been validated through a 4-step scientific approach. It was previously believed that transmission of the bacterium was restricted to much shorter distances. A team of French scientists reviewed the details of an epidemic of Legionnaires' disease that took place in
Pas-de-Calais The Pas-de-Calais (, ' strait of Calais'; ; ) is a department in northern France named after the French designation of the Strait of Dover, which it borders. It has the most communes of all the departments of France, with 890, and is the ...
in northern France in 2003–2004. There were 86 confirmed cases during the outbreak, of whom 18 died. The source of infection was identified as a cooling tower in a
petrochemical Petrochemicals (sometimes abbreviated as petchems) are the chemical products obtained from petroleum by refining. Some chemical compounds made from petroleum are also obtained from other fossil fuels, such as coal or natural gas, or renewable s ...
plant, and an analysis of those affected in the outbreak revealed that some infected people lived as far as 6–7 km from the plant. A study of Legionnaires' disease cases in May 2005 in
Sarpsborg Sarpsborg ( or ), historically Borg, is a List of cities in Norway, city and Municipalities of Norway, municipality in Østfold Counties of Norway, county, Norway. The administrative centre of the municipality is the city of Sarpsborg. Sarpsbor ...
,
Norway Norway, officially the Kingdom of Norway, is a Nordic countries, Nordic country located on the Scandinavian Peninsula in Northern Europe. The remote Arctic island of Jan Mayen and the archipelago of Svalbard also form part of the Kingdom of ...
concluded that: "The high velocity, large drift, and high humidity in the air scrubber may have contributed to the wide spread of ''Legionella'' species, probably for >10 km." In 2010 a study by the UK
Health Protection Agency The Health Protection Agency (HPA) was a non-departmental public body in England. It was set up by the UK government in 2003 to protect the public from threats to their health from infectious diseases and environmental hazards. The HPA's role w ...
reported that 20% of cases may be caused by infected windscreen washer systems filled with pure water. The finding came after researchers spotted that professional drivers are five times more likely to contract the disease. No cases of infected systems were found whenever a suitable washer fluid was used. Temperature affects the survival of ''Legionella'' as follows:
* : Disinfection range * At : Legionellae die within 2 minutes * At : They die within 32 minutes * At : They die within 5 to 6 hours * Above : They can survive but do not multiply * : Ideal growth range * : Growth range * Below : They can survive but are dormant
Removing
slime Slime or slimy may refer to: Science and technology Biology * Slime coat, the coating of mucus covering the body of all fish * Slime mold, an informal name for several eukaryotic organisms * Biofilm, or slime, a syntrophic community of micr ...
, which can carry legionellae when airborne, may be an effective control process.


See also

* Legionnaire's Disease *
Pontiac fever Pontiac fever is an acute, nonfatal respiratory disease caused by various species of Gram-negative bacteria in the genus ''Legionella''. It causes a mild upper respiratory infection that resembles acute influenza. Pontiac fever resolves spontaneo ...
*
1976 Philadelphia Legionnaires' disease outbreak The 1976 Legionnaires' disease outbreak, occurring in the late summer in Philadelphia, Pennsylvania, United States at an annual American Legion convention, was the first occasion in which a Disease cluster, cluster of a particular type of pneumo ...


References


External links

* {{DEFAULTSORT:Legionnaires' disease outbreaks American Legion Building biology Legionellosis Outbreaks Legionellosis Outbreaks Industrial hygiene
Outbreaks In epidemiology, an outbreak is a sudden increase in occurrences of a disease when cases are in excess of normal expectancy for the location or season. It may affect a small and localized group or impact upon thousands of people across an entire ...
Legionnaires' disease outbreaks Lists of disease outbreaks 2005 disasters in Canada 2012 disasters in Canada