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Pontiac Fever
Pontiac fever is an acute, nonfatal respiratory disease caused by various species of Gram-negative bacteria in the genus ''Legionella''. It causes a mild upper respiratory infection that resembles acute influenza. Pontiac fever resolves spontaneously and often goes undiagnosed. Both Pontiac fever and the more severe Legionnaire's disease may be caused by the same bacteria, but Pontiac fever does not include pneumonia. Cause Species of ''Legionella'' known to cause Pontiac fever include ''Legionella pneumophila'', '' Legionella longbeachae'', ''Legionella feeleii'', ''Legionella micdadei'', and '' Legionella anisa''. Sources of the causative agents are aquatic systems and potting soil. The first outbreak caused by inhalation of aerosolized potting soil was discovered in New Zealand in January 2007. A total of 10 workers at a nursery came down with Pontiac fever. It was the first identification of ''L. longbeachae''. Pontiac fever does not spread from person to person. It is acquired ...
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Gram-negative Bacteria
Gram-negative bacteria are bacteria that do not retain the crystal violet stain used in the Gram staining method of bacterial differentiation. They are characterized by their cell envelopes, which are composed of a thin peptidoglycan cell wall sandwiched between an inner cytoplasmic cell membrane and a bacterial outer membrane. Gram-negative bacteria are found in virtually all environments on Earth that support life. The gram-negative bacteria include the model organism ''Escherichia coli'', as well as many pathogenic bacteria, such as ''Pseudomonas aeruginosa'', '' Chlamydia trachomatis'', and ''Yersinia pestis''. They are a significant medical challenge as their outer membrane protects them from many antibiotics (including penicillin), detergents that would normally damage the inner cell membrane, and lysozyme, an antimicrobial enzyme produced by animals that forms part of the innate immune system. Additionally, the outer leaflet of this membrane comprises a complex lipopol ...
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Pontiac, Michigan
Pontiac ( ') is a city in and the county seat of Oakland County in the U.S. state of Michigan. As of the 2020 census, the city had a total population of 61,606. A northern suburb of Metro Detroit, Pontiac is about northwest of Detroit. Founded in 1818, Pontiac was the second European-American organized settlement in Michigan near Detroit, after Dearborn. It was named after Pontiac, a war chief of the Ottawa Tribe, who occupied the area before the European settlers. The city was best known for its General Motors automobile manufacturing plants of the 20th century, which were the basis of its economy and contributed to the wealth of the region. These included Fisher Body, Pontiac East Assembly (a.k.a. Truck & Coach/Bus), which manufactured GMC products, and the Pontiac Motor Division. In the city's heyday, it was the site of the primary automobile assembly plant for the production of the famed Pontiac cars, a brand that was named after the city. The Pontiac brand itself was di ...
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Legionellosis
Legionnaires' disease is a form of atypical pneumonia caused by any species of ''Legionella'' bacteria, quite often '' Legionella pneumophila''. Signs and symptoms include cough, shortness of breath, high fever, muscle pains, and headaches. Nausea, vomiting, and diarrhea may also occur. This often begins 2–10 days after exposure. A legionellosis is any disease caused by ''Legionella'', including Legionnaires' disease (a pneumonia), Pontiac fever (a nonpneumonia illness), and Pittsburgh pneumonia, but Legionnaires' disease is the most common, so mentions of legionellosis often refer to Legionnaires' disease. The bacterium is found naturally in fresh water. It can contaminate hot water tanks, hot tubs, and cooling towers of large air conditioners. It is usually spread by breathing in mist that contains the bacteria. It can also occur when contaminated water is aspirated. It typically does not spread directly between people, and most people who are exposed do not become infect ...
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Industrial Hygiene
Occupational hygiene (United States: industrial hygiene (IH)) is the anticipation, recognition, evaluation, control, and confirmation (ARECC) of protection from hazards at work that may result in injury, illness, or affect the well being of workers. These hazards or stressors are typically divided into the categories biological, chemical, physical, ergonomic and psychosocial. The risk of a health effect from a given stressor is a function of the hazard multiplied by the exposure to the individual or group. For chemicals, the hazard can be understood by the dose response profile most often based on toxicological studies or models. Occupational hygienists work closely with toxicologists (see Toxicology) for understanding chemical hazards, physicists (see Physics) for physical hazards, and physicians and microbiologists for biological hazards (see Microbiology Tropical medicine Infection). Environmental and occupational hygienists are considered experts in exposure science and ex ...
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Building Biology
A building, or edifice, is an enclosed structure with a roof and walls standing more or less permanently in one place, such as a house or factory (although there's also portable buildings). Buildings come in a variety of sizes, shapes, and functions, and have been adapted throughout history for a wide number of factors, from building materials available, to weather conditions, land prices, ground conditions, specific uses, prestige, and aesthetic reasons. To better understand the term ''building'' compare the list of nonbuilding structures. Buildings serve several societal needs – primarily as shelter from weather, security, living space, privacy, to store belongings, and to comfortably live and work. A building as a shelter represents a physical division of the human habitat (a place of comfort and safety) and the ''outside'' (a place that at times may be harsh and harmful). Ever since the first cave paintings, buildings have also become objects or canvasses of much artistic ...
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American Legion
The American Legion, commonly known as the Legion, is a non-profit organization of U.S. war War is an intense armed conflict between states, governments, societies, or paramilitary groups such as mercenaries, insurgents, and militias. It is generally characterized by extreme violence, destruction, and mortality, using regular o ... veterans headquartered in Indianapolis, Indiana. It is made up of state, U.S. territory, and overseas departments, and these are in turn made up of local posts. The organization was formed on March 15, 1919, in Paris, France, by a thousand Officer (armed forces), officers and men of the American Expeditionary Forces (A. E. F.), and it was Congressional charter, chartered on September 16, 1919, by the United States Congress. The Legion played the leading role in the drafting and passing of the Servicemen's Readjustment Act of 1944, commonly known as the "G.I. Bill". In addition to organizing commemorative events, members provide assistanc ...
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Lochgoilhead
Lochgoilhead ( gd, Ceann Loch Goibhle, IPA: ˆkʰʲaun̴̪ˈɫ̪ɔxˈkɤilÉ™ is a village on the Cowal peninsula, in Argyll and Bute, Scottish Highlands. It is located within the Loch Lomond and The Trossachs National Park and is widely considered to be one of the most beautiful areas in Argyll and in Scotland as a whole. Location The village is surrounded by several Corbetts in the Arrochar Alps, including Benn Donich, The Brack and Cnoc Coinnich and local waterways are the River Goil and the Donich Water. The area has been inhabited for over 10,000 years, with the original name for the area being 'Kil nam brathairan' from the Gaelic for 'Church of the brothers'. There are Neolithic remains in the area, including nearby cup marks and a well-preserved corn kiln. The area is associated with the history of Clan Campbell, who drove the Lamonts from the area in the fourteenth century. Lochgoilhead used to be an important stop on the route between Glasgow and Inverary, as tra ...
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1976 Philadelphia Legionnaires' Disease Outbreak
The 1976 Legionnaires disease outbreak, occurring in the late summer in Philadelphia, Pennsylvania, United States was the first occasion in which a cluster of a particular type of pneumonia cases were determined to be caused by the ''Legionella pneumophila'' bacteria. Previous outbreaks were retroactively diagnosed as being most probably caused by Legionella bacteria. Background On July 21, 1976, the American Legion opened its annual three-day convention at the Bellevue-Stratford Hotel in Philadelphia, Pennsylvania. More than 2,000 Legionnaires, mostly men, attended the convention. The date and city were chosen to coincide with America's celebration of the 200th anniversary of the signing of the US Declaration of Independence at Philadelphia in 1776. On July 27, three days after the convention ended, Legionnaire Ray Brennan, a 61-year-old retired US Air Force captain and an American Legion bookkeeper, died at his home of an apparent heart attack. Brennan had returned home from ...
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Aerosolization
Aerosolization is the process or act of converting some physical substance into the form of particles small and light enough to be carried on the air i.e. into an aerosol. Aerosolization refers to a process of intentionally oxidatively converting and suspending particles or a composition in a moving stream of air for the purpose of delivering the oxidized particles or composition to a particular location. The term is often used in medicine to refer specifically to the production of airborne particles (e.g. tiny liquid droplets) containing infectious virus or bacteria. The infectious organism is said to be ''aerosolized''. This can occur when an infected individual coughs, sneezes exhales, or vomits, but can also arise from flushing a toilet, or disturbing dried contaminated feces. Treatment of some respiratory diseases relies on aerosolization of a liquid medication using a nebulizer, which is then breathed in for direct transport to the lungs. In the context of chemical and biolo ...
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Legionella
''Legionella'' is a genus of pathogenic gram-negative bacteria that includes the species '' L. pneumophila'', causing legionellosis (all illnesses caused by ''Legionella'') including a pneumonia-type illness called Legionnaires' disease and a mild flu-like illness called Pontiac fever. ''Legionella'' may be visualized with a silver stain or cultured in cysteine-containing media such as buffered charcoal yeast extract agar. It is common in many environments, including soil and aquatic systems, with at least 50 species and 70 serogroups identified. These bacteria, however, are not transmissible from person to person; furthermore, most people exposed to the bacteria do not become ill. Most outbreaks are traced to poorly maintained cooling towers. The side chains of the cell wall carry the bases responsible for the somatic antigen specificity of these organisms. The chemical composition of these side chains both with respect to components and arrangement of the different sugars de ...
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Legionella Anisa
''Legionella anisa'' is a Gram-negative bacterium, one of more than 40 species in the family Legionellaceae. After ''Legionella pneumophila'', this species has been isolated most frequently from water samples. This species is also one of the several pathogenic forms of ''Legionella'' having been associated with rare clinical cases of illness including Pontiac fever and Legionnaires' disease. History This species was first isolated from water during a nosocomial outbreak in the United States between March 1980 and June 1981. The type strain of ''L. anisa'' is WA-316-C3 (ATCC 35292). The first reported clinical detection was in 1986, with a female patient in Victoria, Australia, who presented with pneumonia. Similar to other ''Legionella'' species, person-to-person transmission has not been documented. Structure Like other ''Legionella'' species, ''L. anisa'' is a thin, aerobic, pleomorphic, flagellated, non-spore-forming, Gram-negative bacterium. A distinguishing characteristic ...
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Legionella Micdadei
''Legionella micdadei'' is a Gram-negative bacterium from the genus ''Legionella'', which stains acid-fast Acid-fastness is a physical property of certain bacterial and eukaryotic cells, as well as some sub-cellular structures, specifically their resistance to decolorization by acids during laboratory staining procedures. Once stained as part of a sam .... It stains weakly, but loses this trait upon being grown in culture. ''Tatlockia micdadei'' is an alternative term for ''L. micdadei'', the Pittsburgh pneumonia agent and TATLOCK strain.McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc. It is named after Joseph E. McDade, who first isolated ''L. pneumophila''. References Legionellales {{Legionellales-stub ...
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