This is a list of human

pseudogene Pseudogenes are nonfunctional segments of DNA that resemble functional genes. Most arise as superfluous copies of functional genes, either directly by DNA duplication or indirectly by Reverse transcriptase, reverse transcription of an mRNA trans ...

s that are known to be disabled genes. *

WNT3A Protein Wnt-3a is a protein that in humans is encoded by the ''WNT3A'' gene. The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have are critical in tissue homeostasis, embryonic de ...

pseudogene, associated with the growth of a tail * NCF1C pseudogene, associated with a type of white blood cell. It makes part of the

neutrophil Neutrophils (also known as neutrocytes or heterophils) are the most abundant type of granulocytes and make up 40% to 70% of all white blood cells in humans. They form an essential part of the innate immune system, with their functions varying in ...

NADPH Nicotinamide adenine dinucleotide phosphate, abbreviated NADP or, in older notation, TPN (triphosphopyridine nucleotide), is a cofactor used in anabolic reactions, such as the Calvin cycle and lipid and nucleic acid syntheses, which require NAD ...

oxidase enzyme, which makes

superoxide In chemistry, a superoxide is a compound that contains the superoxide ion, which has the chemical formula . The systematic name of the anion is dioxide(1−). The reactive oxygen ion superoxide is particularly important as the product of the ...

anion. *

GULO ''Gulo'' is a genus of carnivoran mammals in the family Mustelidae. It contains one extant species, the wolverine (''G. gulo''), as well as several extinct ones. Fossil evidence suggests that this genus appeared in North America and later sprea ...

pseudogene, associated with the production of Vitamin C * IRGM pseudogene, associated with the immune system *

hHaA KRT41P, formerly KRTHAP1 (also known as ΨhHaA, ''h'' prefix for "human") is a human pseudogene that used to code for a keratin. It is believed to be responsible for fur-like body hair Body hair, or androgenic hair, is the terminal hair that ...

pseudogene, associated with fur-like body hair: see

hypertrichosis Hypertrichosis is an abnormal amount of hair growth over the body. The two distinct types of hypertrichosis are generalized hypertrichosis, which occurs over the entire body, and localized hypertrichosis, which is restricted to a certain area. H ...

* DEFT1P pseudogene, associated with the immune system *

Urate oxidase The enzyme urate oxidase (UO), uricase or factor-independent urate hydroxylase, absent in humans, catalyzes the oxidation of uric acid to 5-hydroxyisourate: :Uric acid + O2 + H2O → 5-hydroxyisourate + H2O2 : 5-hydroxyisourate + H2O → al ...

pseudogene, associated with the processing of uric acid *

Photolyase Photolyases () are DNA repair enzymes that repair damage caused by exposure to ultraviolet light. These enzymes require visible light (from the violet/blue end of the spectrum) both for their own activation and for the actual DNA repair. The DN ...

pseudogene, associated with repairing DNA damaged by UV radiation ** Photolyase is no longer encoded for despite obvious advantages. Instead, this gene is mutated to encode for

cryptochrome Cryptochromes (from the Greek κρυπτός χρώμα, "hidden colour") are a class of flavoproteins found in plants and animals that are sensitive to blue light. They are involved in the circadian rhythms and the sensing of magnetic fields i ...

References

{{DEFAULTSORT:Disabled human pseudogenes

Pseudo The prefix pseudo- (from Greek ψευδής, ''pseudes'', "false") is used to mark something that superficially appears to be (or behaves like) one thing, but is something else. Subject to context, ''pseudo'' may connote coincidence, imitation, ...