Leonard Rowntree
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Leonard George Rowntree (1883–1959) was a
Canadian Canadians (french: Canadiens) are people identified with the country of Canada. This connection may be residential, legal, historical or cultural. For most Canadians, many (or all) of these connections exist and are collectively the source of ...
physician and medical researcher who was credited with founding the research tradition at the
Mayo Clinic The Mayo Clinic () is a nonprofit American academic medical center focused on integrated health care, education, and research. It employs over 4,500 physicians and scientists, along with another 58,400 administrative and allied health staff, ...
. He is most well known for pioneering kidney research including the Rowntree test for kidney function; dialysis; the
intravenous pyelogram Pyelogram (or pyelography or urography) is a form of imaging of the renal pelvis and ureter. Types include: * Intravenous pyelogram – In which a contrast solution is introduced through a vein into the circulatory system. * Retrograde pyelogram ...
and
plasmapheresis Plasmapheresis (from the Greek πλάσμα, ''plasma'', something molded, and ἀφαίρεσις ''aphairesis'', taking away) is the removal, treatment, and return or exchange of blood plasma or components thereof from and to the blood circulati ...
. Rowntree was awarded the
Medal for Merit The Medal for Merit was, during the period it was awarded, the highest civilian decoration of the United States. It was awarded by the President of the United States to civilians who "distinguished themselves by exceptionally meritorious conduct i ...
in 1946.


Early life

Rowntree was born in
London, Ontario London (pronounced ) is a city in southwestern Ontario, Canada, along the Quebec City–Windsor Corridor. The city had a population of 422,324 according to the 2021 Canadian census. London is at the confluence of the Thames River, approximate ...
, on April 10, 1883. He entered
University of Western Ontario The University of Western Ontario (UWO), also known as Western University or Western, is a Public university, public research university in London, Ontario, London, Ontario, Canada. The main campus is located on of land, surrounded by resident ...
medical school in 1901, graduating in 1905 with the gold medal. He interned at Victoria Hospital and then entered general practice in
Camden, New Jersey Camden is a city in and the county seat of Camden County, in the U.S. state of New Jersey. Camden is part of the Delaware Valley metropolitan area and is located directly across the Delaware River from Philadelphia, Pennsylvania. At the 2020 ...
. A year later he attended a lecture given by
William Osler Sir William Osler, 1st Baronet, (; July 12, 1849 – December 29, 1919) was a Canadian physician and one of the "Big Four" founding professors of Johns Hopkins Hospital. Osler created the first Residency (medicine), residency program for spec ...
in
Philadelphia Philadelphia, often called Philly, is the largest city in the Commonwealth of Pennsylvania, the sixth-largest city in the U.S., the second-largest city in both the Northeast megalopolis and Mid-Atlantic regions after New York City. Sinc ...
. He approached Osler about his career.


Academic career

Osler recommended Rowntree to
Johns Hopkins Hospital The Johns Hopkins Hospital (JHH) is the teaching hospital and biomedical research facility of the Johns Hopkins School of Medicine, located in Baltimore, Maryland, U.S. It was founded in 1889 using money from a bequest of over $7 million (1873 mo ...
where he worked with John J. Abel, a prominent pharmacologist. Abel introduced him to phthalein, from which he and J. T. Geraghty developed the Rowntree test of renal function. With Norman Keith of Toronto, Rowntree invented a method to calculate blood and plasma volume using a red dye dilution method. Abel and Rowntree also developed the first artificial kidney, also known as dialysis, in 1913. From 1915 to 1918, Rowntree was head of medicine at the
University of Minnesota The University of Minnesota, formally the University of Minnesota, Twin Cities, (UMN Twin Cities, the U of M, or Minnesota) is a public university, public Land-grant university, land-grant research university in the Minneapolis–Saint Paul, Tw ...
. The next year the team described plasmapheresis. In 1918, he joined the US Army where he led studies of
aviation medicine Aviation medicine, also called flight medicine or aerospace medicine, is a preventive or occupational medicine in which the patients/subjects are pilots, aircrews, or astronauts. The specialty strives to treat or prevent conditions to which aircr ...
. That year
William James Mayo William James Mayo (June 29, 1861 – July 28, 1939) was a physician and surgeon in the United States and one of the seven founders of the Mayo Clinic. He and his brother, Charles Horace Mayo, both joined their father's private medical practic ...
saved his life by performing surgery on him for a perforated ulcer. In 1920, Rowntree was made Head of Section and Professor of Medicine of the Mayo Foundation. He recruited what became known as the "Rowntree group" to the
Mayo Clinic The Mayo Clinic () is a nonprofit American academic medical center focused on integrated health care, education, and research. It employs over 4,500 physicians and scientists, along with another 58,400 administrative and allied health staff, ...
including Norman Keith of Toronto, Samuel Amberg of Chicago, and Reginald Fitz of Boston, all of whom had been collaborators with his at Hopkins, and later Henry Helmholtz, George Brown, Walter Alvarez, Russell Wilder, Stanley McVicar, Albert M. Snell, Jay Bargen, Carl Greene,
Philip Hench Philip Showalter Hench (February 28, 1896 – March 30, 1965) was an American physician. Hench, along with his Mayo Clinic co-worker Edward Calvin Kendall and Swiss chemist Tadeus Reichstein was awarded the Nobel Prize for Physiology or Medicine ...
, Bayard Horton. During his 12 years at the clinic, he published more than 100 articles, primarily in the fields of endocrine disease, water metabolism, and hepatology including the treatment of
Addison's disease Addison's disease, also known as primary adrenal insufficiency, is a rare long-term endocrine disorder characterized by inadequate production of the steroid hormones cortisol and aldosterone by the two outer layers of the cells of the adrenal ...
with adrenal extracts and the radiological technique to xray the kidneys known as the
intravenous pyelogram Pyelogram (or pyelography or urography) is a form of imaging of the renal pelvis and ureter. Types include: * Intravenous pyelogram – In which a contrast solution is introduced through a vein into the circulatory system. * Retrograde pyelogram ...
Rowntree left the Mayo clinic in 1932 to continue his illustrious career in medicine as director of the Philadelphia Institute for Medical Research. During WW II, Rowntree with two colleagues presented information on the physical status of
Selective Service The Selective Service System (SSS) is an independent agency of the United States government that maintains information on U.S. citizens and other U.S. residents potentially subject to military conscription (i.e., the draft) and carries out contin ...
registrants; he also considered the information's implications for health needs.


History of Medicine

In 1911, Rowntree explored the sites of
James Parkinson James Parkinson (11 April 175521 December 1824) was an English surgeon, apothecary, geologist, palaeontologist and political activist. He is best known for his 1817 work ''An Essay on the Shaking Palsy'', in which he was the first to describe ...
's life in
London London is the capital and largest city of England and the United Kingdom, with a population of just under 9 million. It stands on the River Thames in south-east England at the head of a estuary down to the North Sea, and has been a majo ...
. He commented that Parkinson had been forgotten even though he had described the eponymous condition known as
Parkinson's disease Parkinson's disease (PD), or simply Parkinson's, is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms usually emerge slowly, and as the disease worsens, non-motor symptoms becom ...
Rowntree's life of James Parkinson has been the basis of biographies since then.


Awards and distinctions

Rowntree was elected an honorary member of the
Harvey Club of London The Harvey Club of London is the oldest currently active medical club in Canada. It was founded by Drs. James W. Crane and C.M. Crawford in 1919 in London, Ontario. The club was initially founded as a way for practicing physicians to stay abreast ...
in 1922. The
University of Western Ontario The University of Western Ontario (UWO), also known as Western University or Western, is a Public university, public research university in London, Ontario, London, Ontario, Canada. The main campus is located on of land, surrounded by resident ...
awarded him an honorary Doctor of Science degree in 1916 and established the annual Rowntree prize to the best essay on the history of medicine by a medical student. In 1944, he won the Banting Medal of the
American Diabetes Association The American Diabetes Association (ADA) is a United States-based nonprofit that seeks to educate the public about diabetes and to help those affected by it through funding research to manage, cure and prevent diabetes (including type 1 diabetes, ...
. In 1946, President
Harry Truman Harry S. Truman (May 8, 1884December 26, 1972) was the 33rd president of the United States, serving from 1945 to 1953. A leader of the Democratic Party, he previously served as the 34th vice president from January to April 1945 under Franklin ...
awarded Rowntree the
Medal for Merit The Medal for Merit was, during the period it was awarded, the highest civilian decoration of the United States. It was awarded by the President of the United States to civilians who "distinguished themselves by exceptionally meritorious conduct i ...
for his work as chief of the medical division of the
Selective Service System The Selective Service System (SSS) is an Independent agencies of the United States government, independent agency of the Federal government of the United States, United States government that maintains information on U.S. Citizenship of the Unite ...
from 1940 to 1945.


References

{{DEFAULTSORT:Rowntree, Leonard 1883 births 1959 deaths 20th-century Canadian physicians Canadian medical researchers Physicians of the Mayo Clinic University of Western Ontario alumni