The law of specific nerve energies, first proposed by
Johannes Peter Müller
Johannes Peter Müller (14 July 1801 – 28 April 1858) was a German physiologist, comparative anatomy, comparative anatomist, ichthyology, ichthyologist, and herpetology, herpetologist, known not only for his discoveries but also for his ability ...
in 1835, is that the nature of perception is defined by the pathway over which the sensory information is carried. Hence, the origin of the sensation is not important. Therefore, the difference in perception of seeing, hearing, and touch are not caused by differences in the stimuli themselves but by the different nervous structures that these stimuli excite. For example, pressing on the
eye elicits sensations of flashes of
light
Light or visible light is electromagnetic radiation that can be perceived by the human eye. Visible light is usually defined as having wavelengths in the range of 400–700 nanometres (nm), corresponding to frequencies of 750–420 tera ...
because the
neuron
A neuron, neurone, or nerve cell is an electrically excitable cell that communicates with other cells via specialized connections called synapses. The neuron is the main component of nervous tissue in all animals except sponges and placozoa. N ...
s in the
retina
The retina (from la, rete "net") is the innermost, light-sensitive layer of tissue of the eye of most vertebrates and some molluscs. The optics of the eye create a focused two-dimensional image of the visual world on the retina, which then ...
send a signal to the
occipital lobe
The occipital lobe is one of the four major lobes of the cerebral cortex in the brain of mammals. The name derives from its position at the back of the head, from the Latin ''ob'', "behind", and ''caput'', "head".
The occipital lobe is the vi ...
. Despite the sensory input's being mechanical, the experience is visual.
Quotation
Here is Müller's statement of the law, from ''Handbuch der Physiologie des Menschen für Vorlesungen'', 2nd Ed., translated by Edwin Clarke and Charles Donald O'Malley:
::''The same cause, such as electricity, can simultaneously affect all sensory organs, since they are all sensitive to it; and yet, every sensory nerve reacts to it differently; one nerve perceives it as light, another hears its sound, another one smells it; another tastes the electricity, and another one feels it as pain and shock. One nerve perceives a luminous picture through mechanical irritation, another one hears it as buzzing, another one senses it as pain. . . He who feels compelled to consider the consequences of these facts cannot but realize that the specific sensibility of nerves for certain impressions is not enough, since all nerves are sensitive to the same cause but react to the same cause in different ways. . . (S)ensation is not the conduction of a quality or state of external bodies to consciousness, but the conduction of a quality or state of our nerves to consciousness, excited by an external cause.''
Clarification
As the above quotation shows, Müller's law seems to differ from the modern statement of the law in one key way. Müller attributed the
quality
Quality may refer to:
Concepts
*Quality (business), the ''non-inferiority'' or ''superiority'' of something
*Quality (philosophy), an attribute or a property
*Quality (physics), in response theory
*Energy quality, used in various science discipli ...
of an experience to some specific quality of the energy in the nerves. For example, the visual experience from light shining into the eye, or from a poke in the eye, arises from some special quality of the energy carried by
optic nerve
In neuroanatomy, the optic nerve, also known as the second cranial nerve, cranial nerve II, or simply CN II, is a paired cranial nerve that transmits visual system, visual information from the retina to the brain. In humans, the optic nerve i ...
, and the auditory experience from sound coming into the ear, or from electrical stimulation of the
cochlea
The cochlea is the part of the inner ear involved in hearing. It is a spiral-shaped cavity in the bony labyrinth, in humans making 2.75 turns around its axis, the modiolus. A core component of the cochlea is the Organ of Corti, the sensory org ...
, arises from some different, special quality of the energy carried by the
auditory nerve
The cochlear nerve (also auditory nerve or acoustic nerve) is one of two parts of the vestibulocochlear nerve, a cranial nerve present in amniotes, the other part being the vestibular nerve. The cochlear nerve carries auditory sensory information ...
. In 1912,
Lord Edgar Douglas Adrian showed that all neurons carry the same energy, electrical energy in the form of
action potential
An action potential occurs when the membrane potential of a specific cell location rapidly rises and falls. This depolarization then causes adjacent locations to similarly depolarize. Action potentials occur in several types of animal cells, ...
s. That means that the quality of an experience depends on the part of the brain to which nerves deliver their action potentials (e.g., light from nerves arriving at the
visual cortex
The visual cortex of the brain is the area of the cerebral cortex that processes visual information. It is located in the occipital lobe. Sensory input originating from the eyes travels through the lateral geniculate nucleus in the thalamus and ...
and sound from nerves arriving at the
auditory cortex
The auditory cortex is the part of the temporal lobe that processes auditory information in humans and many other vertebrates. It is a part of the auditory system, performing basic and higher functions in hearing, such as possible relations to ...
).
In 1945,
Roger Sperry
Roger Wolcott Sperry (August 20, 1913 – April 17, 1994) was an American neuropsychologist, neurobiologist, cognitive neuroscientist, and Nobel laureate who, together with David Hunter Hubel and Torsten Nils Wiesel, won the 1981 Nobel Prize ...
showed that it is the location in the brain to which nerves attach that determines experience. He studied
amphibian
Amphibians are tetrapod, four-limbed and ectothermic vertebrates of the Class (biology), class Amphibia. All living amphibians belong to the group Lissamphibia. They inhabit a wide variety of habitats, with most species living within terres ...
s whose optic nerves cross completely, so that the left eye connects to the right side of the brain and the right eye connects to the left side of the brain. He was able to cut the optic nerves and cause them to regrow on the opposite side of the brain so that the left eye now connected to the left side of the brain and the right eye connected to the right side of the brain. He then showed that these animals made the opposite movements from the ones they would have made before the operation. For example, before the operation, the animal would move to the left to get away from a large object approaching from the right. After the operation, the animal would move to the right in response to the same large object approaching from the right. Sperry showed similar results in other animals including
mammal
Mammals () are a group of vertebrate animals constituting the class Mammalia (), characterized by the presence of mammary glands which in females produce milk for feeding (nursing) their young, a neocortex (a region of the brain), fur or ...
s (
rats), this work contributing to his
Nobel Prize
The Nobel Prizes ( ; sv, Nobelpriset ; no, Nobelprisen ) are five separate prizes that, according to Alfred Nobel's will of 1895, are awarded to "those who, during the preceding year, have conferred the greatest benefit to humankind." Alfr ...
in 1981.
References
#Norrsell U., Finger S. and Lajonchere C. (1999) Cutaneous sensory spots and the "law of specific nerve energies": history and development of ideas. ''Brain Research Bulletin, 48''(5): 457-465.
#Sperry, R. W. (1945). Restoration of vision after crossing of optic nerves and after transplantation of eye. ''Journal of Neurophysiology, 8'', 15-28.
#
Uexküll, Jakob von (1947). ''Der Sinn des Lebens: Gedanken über die Aufgaben der Biologie. (Mitgeteilt in einer Interpretation der zu Bonn 1824 gehaltenen Vorlesung des Johannes Müller 'Von dem Bedürfnis der Physiologie nach einer philosophischen Naturbetrachtung', mit einem Ausblick von Thure von Uexküll.)'' Godesberg: Verlag Helmut Küpper.
{{DEFAULTSORT:Law Of Specific Nerve Energies
Sensory systems
Biology theories