Joy Wolfram
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Joy Wolfram (born 1989) is a Finnish nanoscientist. She is known for her pioneering work in nanomedicine concerning the treatment of cancer,
cardiovascular The blood circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the entire body of a human or other vertebrate. It includes the cardiovascular system, or vascular system, tha ...
diseases and other life-threatening illnesses. She is an Associate Professor at the
University of Queensland , mottoeng = By means of knowledge and hard work , established = , endowment = A$224.3 million , budget = A$2.1 billion , type = Public research university , chancellor = Peter Varghese , vice_chancellor = Deborah Terry , city = B ...
, in the school of Chemical Engineering and the
Australian Institute for Bioengineering and Nanotechnology The University of Queensland's Australian Institute for Bioengineering and Nanotechnology (AIBN) was established in 2003. It is one of four stand-alone research institutions at the university with more than 500 researchers, students and support ...
. She was the forefront of the
Extracellular Vesicles Extracellular vesicles (EVs) are lipid bilayer-delimited particles that are naturally released from almost all types of cell but, unlike a cell, cannot replicate. EVs range in diameter from near the size of the smallest physically possible unilame ...
and
Nanomedicine Nanomedicine is the medical application of nanotechnology. Nanomedicine ranges from the medical applications of nanomaterials and biological devices, to nanoelectronic biosensors, and even possible future applications of molecular nanotech ...
laboratory at Mayo Clinic. She is also an affiliate faculty member at
Houston Methodist Hospital Houston Methodist Hospital is the flagship quaternary care hospital of Houston Methodist academic medical center. Located in the Texas Medical Center in Houston, Texas, Houston Methodist Hospital was established in 1919 during the height of the ...
's Department of Nanomedecine. Wolfram sits as a scientific advisor and as a board member of several
biotechnology Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used ...
companies around the world.


Personal life

Wolfram was born and raised in Finland. Her father is Ben Wolfram and her mother is artist Maria Wolfram. Wolfram's interest in science started at 11 years old after seeing the swab cultures of her dog's infection seeded in bacterial plates. She was fascinated that she asked the veterinarian if she may have culture supplies, and the veterinarian refused but later decided to give her in private. Wolfram then built her miniature microbiology laboratory. Her first experiment was swabbing shelves in their refrigerator. The bacterial plates were later covered with different shapes and various colors, and she thought it was cool even after it horrified her family as she announced that their fridge was crawling with bacteria. In 2018, Wolfram's friend, Rebecca, succumbed to recurring cancer. The experience further motivated her on her cancer treatment research via nanotechnology.


Education

In 2010, Wolfram graduated with a master's degree in Biology from the
University of Helsinki The University of Helsinki ( fi, Helsingin yliopisto, sv, Helsingfors universitet, abbreviated UH) is a public research university located in Helsinki, Finland since 1829, but founded in the city of Turku (in Swedish ''Åbo'') in 1640 as the ...
. She was also a part-time researcher at the University's Institute of
Biotechnology Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used ...
. In 2016, Wolfram earned a Ph.D. in Nanotechnology from the
University of Chinese Academy of Sciences The University of the Chinese Academy of Sciences (UCAS; ) is a public university for graduate education, under the direct leadership of the Chinese Academy of Sciences (CAS). The predecessors of UCAS are the Graduate University of the Chinese ...
.


Career and research

Wolfram was an
Amgen Amgen Inc. (formerly Applied Molecular Genetics Inc.) is an American multinational biopharmaceutical company headquartered in Thousand Oaks, California. One of the world's largest independent biotechnology companies, Amgen was established in T ...
Scholar and she participated in a research at
Karolinska Institute The Karolinska Institute (KI; sv, Karolinska Institutet; sometimes known as the (Royal) Caroline Institute in English) is a research-led Medical school, medical university in Solna Municipality, Solna within the Stockholm urban area of Sweden. ...
in 2009 regarding a novel protein that increases the migration of cancer cells. The program solidified her desire to study translational cancer. She has been a visiting scholar at the Department of Molecular and Cellular Biology Research, Sunnybrook Health Sciences Centre,
Toronto Toronto ( ; or ) is the capital city of the Canadian province of Ontario. With a recorded population of 2,794,356 in 2021, it is the most populous city in Canada and the fourth most populous city in North America. The city is the anch ...
,
Canada Canada is a country in North America. Its ten provinces and three territories extend from the Atlantic Ocean to the Pacific Ocean and northward into the Arctic Ocean, covering over , making it the world's second-largest country by tot ...
, in 2010, investigating antiangiogenic receptor tyrosine kinase inhibitors. Wolfram began working as a research fellow for cancer and nanomedicine at the Houston Methodist Hospital in 2011. As she obtained her Ph.D. degree in 2016 she became a postdoctoral fellow. Wolfram worked as an Associate Research Professor at the Wenzhou Institute of Biomaterials and Engineering from 2017–2019. In 2017, she began holding affiliate faculty positions at the Houston Methodist's Department of Nanomedicine and at the
University of North Florida The University of North Florida (UNF) is a public research university in Jacksonville, Florida. It is part of the State University System of Florida and is accredited by the Commission on Colleges of the Southern Association of Colleges and Sc ...
's Department of Biology. In the same year she also became as an Assistant Professor of Medicine at Mayo Clinic, where she has been the director of the Nanomedicine and Extracellular Vesicles Laboratory until January 2022. Her research programs are dedicated for the detection, diagnosis and treatment of various diseases. Her research aims to produce nanomedicine with increased therapeutic properties to suppress side effects. Wolfram had come up with strategies for modulating the immune system to allow accurate drug delivery to tumors, particularly through the use of
chloroquine Chloroquine is a medication primarily used to prevent and treat malaria in areas where malaria remains sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medi ...
or through the body's own nanoparticles. In her
TED TED may refer to: Economics and finance * TED spread between U.S. Treasuries and Eurodollar Education * ''Türk Eğitim Derneği'', the Turkish Education Association ** TED Ankara College Foundation Schools, Turkey ** Transvaal Education Depa ...
talk Wolfram notes that there are over 10 clinically approved nanoparticles for treating cancer. Despite her young age, she has already authored over 60 publications on nanoscale strategies for cancer and other life-threatening diseases, received more than 30 awards and given many important conference talks around the world. As of March 2023, she has an h-index of 40. She was also named Finnish Expatriate of the Year in 2021.


Other activities

Wolfram is an advocate for increasing diversity in science, especially with underrepresented gender and racial minorities. She is also active in community outreach programs. Since 2016, she has been the representative of the Education and Outreach Unit of the National Cancer Institute's Center for Immunotherapeutic Transport Oncophysics at the Houston Methodist Research Institute.


Honors & awards

*Award for Excellence in Scientific Productivity, Houston Methodist Research Institute, 2016 *Amgen Scholars Ten to Watch List,
Amgen Amgen Inc. (formerly Applied Molecular Genetics Inc.) is an American multinational biopharmaceutical company headquartered in Thousand Oaks, California. One of the world's largest independent biotechnology companies, Amgen was established in T ...
Foundation, 2016 *Junior Investigator Travel Award, Sage Assembly, 2017 *Internationally Accomplished Finn, Finland, 2017 *Judge Travel Award, Annual Biomedical Research Conference for Minority Students, 2018 *Big Impact in Bio, Amgen Foundation, 2018 *Finland's Ten Outstanding Young Persons in The World, Junior Chamber International Finland, 2019 *
Forbes 30 Under 30 ''Forbes'' 30 Under 30 is a set of lists of people under 30 years old issued annually by ''Forbes'' magazine and some of its regional editions. The American lists recognize 600 business and industry figures, with 30 selected in twenty industries ...
, US & Canada, 2019 *Shortlisted for Nature Research Award,
Nature Publishing Group Nature Portfolio (formerly known as Nature Publishing Group and Nature Research) is a division of the international scientific publishing company Springer Nature that publishes academic journals, magazines, online databases, and services in scie ...
, 2019 *Rising Star in Cancer Research, The Scientist, 2020


References

{{DEFAULTSORT:Wolfram, Joy 1989 births Living people University of Helsinki alumni 20th-century American scientists 21st-century women scientists 20th-century biologists Finnish women scientists


External links


Wolfram Group

Google Scholar