Jack Martin Cuzick (born 11 August 1948) is an American-born British academic, director of the Wolfson Institute of Preventive Medicine in London and head of the Centre for Cancer Prevention. He is the John Snow Professor of Epidemiology at the Wolfson Institute,

Queen Mary University of London , mottoeng = With united powers , established = 1785 – The London Hospital Medical College1843 – St Bartholomew's Hospital Medical College1882 – Westfield College1887 – East London College/Queen Mary College , type = Public researc ...

Education and early life

Cuzick was born in

Hawthorne, California Hawthorne is a city in the Los Angeles metropolitan area, located in southwestern Los Angeles County, California. It is part of a seventeen-city region commonly called the South Bay. As of the 2020 US census, Hawthorne had a population of 88, ...

and attended

El Segundo High School El Segundo High School, or ESHS, is a four-year public high school located in El Segundo, California. It is the only secondary school incorporated by El Segundo Unified School District. First built in 1927, the school campus contains 5 main build ...

. He was awarded a Bachelor of Science degree in Mathematics and Physics in 1970 by the Harvey Mudd College and a Ph.D. in mathematics by

Claremont Graduate School The Claremont Graduate University (CGU) is a private, all-graduate research university in Claremont, California. Founded in 1925, CGU is a member of the Claremont Colleges which includes five undergraduate ( Pomona College, Claremont McKenna C ...

in 1974.

Research and career

He worked on the mathematical analysis of clinical trial methodology at

Columbia University Columbia University (also known as Columbia, and officially as Columbia University in the City of New York) is a private research university in New York City. Established in 1754 as King's College on the grounds of Trinity Church in Manhatt ...

in New York City in the late 1970s and moved to

Oxford University Oxford () is a city in England. It is the county town and only city of Oxfordshire. In 2020, its population was estimated at 151,584. It is north-west of London, south-east of Birmingham and north-east of Bristol. The city is home to the ...

in 1978 to work with cancer epidemiologist

Richard Doll Sir William Richard Shaboe Doll (28 October 1912 – 24 July 2005) was a British physician who became an epidemiologist in the mid-20th century and made important contributions to that discipline. He was a pioneer in research linking smoking ...

. He is involved in the collection and analysis of data for cancer prevention and screening, particularly for breast, cervical and

bowel cancer Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum (parts of the large intestine). Signs and symptoms may include blood in the stool, a change in bowel m ...

s. He is best known for his role conducting the IBIS trials of

tamoxifen Tamoxifen, sold under the brand name Nolvadex among others, is a selective estrogen receptor modulator used to prevent breast cancer in women and treat breast cancer in women and men. It is also being studied for other types of cancer. It has b ...

and

aromatase inhibitors Aromatase inhibitors (AIs) are a class of drugs used in the treatment of breast cancer in postmenopausal women and in men, and gynecomastia in men. They may also be used off-label to reduce estrogen conversion when supplementing testosterone ...

for

chemoprevention Chemoprevention (also chemoprophylaxis) refers to the administration of a medication for the purpose of preventing disease or infection. Antibiotics, for example, may be administered to patients with disorders of immune system function to preven ...

of breast cancer in women with high risk of developing the disease. For this research, Cuzick's team won

Cancer Research UK Cancer Research UK (CRUK) is the world's largest independent cancer research organization. It is registered as a charity in the United Kingdom and Isle of Man, and was formed on 4 February 2002 by the merger of The Cancer Research Campaign and t ...

's Translational Cancer Research Prize in 2014,

Honours and awards

* 2017 Cancer Research UK Lifetime Achievement in Cancer Research Prize * 2016 Elected Fellow of the Royal Society. * 2015 Cuzick received the American Cancer Society Medal of Honor. * 2014 Cancer Research UK Translational Cancer Research Team Prize * 2003 Elected Fellow of the

Academy of Medical Sciences The Academy of Medical Sciences is an organisation established in the UK in 1998. It is one of the four UK National Academies, the others being the British Academy, the Royal Academy of Engineering and the Royal Society. Its mission is to adv ...

* Cuzick was appointed

Commander of the Order of the British Empire The Most Excellent Order of the British Empire is a British order of chivalry, rewarding contributions to the arts and sciences, work with charitable and welfare organisations, and public service outside the civil service. It was established ...

(CBE) in the 2017 New Year Honours for services to cancer prevention and screening.

References

External links

* 1948 births Living people People from Hawthorne, California Cancer epidemiologists British medical researchers Academics of Queen Mary University of London Fellows of the Royal Society Commanders of the Order of the British Empire El Segundo High School alumni Naturalised citizens of the United Kingdom {{UK-med-bio-stub