Reed McNeil Izatt (born 10 October 1926 in

Logan, Utah Logan is a city in Cache County, Utah, United States. The 2020 census recorded the population was 52,778. Logan is the county seat of Cache County and the principal city of the Logan metropolitan area, which includes Cache County and Franklin ...

) is a Charles E. Maw Professor of Chemistry,

Emeritus ''Emeritus'' (; female: ''emerita'') is an adjective used to designate a retired chair, professor, pastor, bishop, pope, director, president, prime minister, rabbi, emperor, or other person who has been "permitted to retain as an honorary title ...

, at Brigham Young University in

Provo, Utah Provo ( ) is the fourth-largest city in Utah, United States. It is south of Salt Lake City along the Wasatch Front. Provo is the largest city and county seat of Utah County and is home to Brigham Young University (BYU). Provo lies between the ...

. His field of research was macrocyclic

chemistry Chemistry is the science, scientific study of the properties and behavior of matter. It is a natural science that covers the Chemical element, elements that make up matter to the chemical compound, compounds made of atoms, molecules and ions ...

and metal separation technologies.

Early life and education

Izatt was born in 1926 in

. His first ten years were spent on a ranch in Sumpter Valley, Oregon where he attended school in a two-room schoolhouse. He developed an interest in geology and astronomy. His family then returned to Logan, Utah and he graduated from Logan High School in 1944. On 6 June 1944, Izatt enrolled at Utah State Agricultural College (now Utah State University). In 1945 and 1946, Izatt served in the United States Army and from 1947 to 1949, he was a missionary in the United Kingdom for the Church of Jesus Christ of Latter-day Saints. While stationed at Fort Douglas, Izatt studied at the University of Utah and in 1951, he received a bachelor of science in

. Izatt took post graduate studies in chemistry at

Pennsylvania State University The Pennsylvania State University (Penn State or PSU) is a Public university, public Commonwealth System of Higher Education, state-related Land-grant university, land-grant research university with campuses and facilities throughout Pennsylvan ...

. He was mentored by W. Conard Fernelius and in 1954 received a doctorate degree.

Career

Izatt worked at the Mellon Institute for Industrial Research (now part of

Carnegie Mellon University Carnegie Mellon University (CMU) is a private research university in Pittsburgh, Pennsylvania. One of its predecessors was established in 1900 by Andrew Carnegie as the Carnegie Technical Schools; it became the Carnegie Institute of Technology ...

) for two years before taking a faculty position in the department of chemistry at Brigham Young University (BYU). He retired from BYU in 1993 as the Charles E. Maw Professor of Chemistry. Izatt and James J. Christensen, a chemical engineer, founded a thermochemical institute at BYU to promote and facilitate interdisciplinary research.

Awards

Izatt is a fellow of the

American Association for the Advancement of Science The American Association for the Advancement of Science (AAAS) is an American international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific respons ...

(1982). He was the BYU Annual Faculty Lecture in 1970. Izatt received the Utah Award (1971) (Salt Lake Section, American Chemical Society); the Huffman Award (1983) (Calorimetry Conference); the American Chemical Society Separations Science and Technology Award (1996); the

Utah Governor's Medal for Science and Technology The Utah Governor's Medal for Science and Technology is the highest civilian award bestowed by the U.S. state of Utah in those fields. It is awarded in the five categories of academia, science education, industry, government, and a special category. ...

(1990); and the First Annual Alumni Achievement Award (2001) (Utah State University Department of Chemistry and Biochemistry).

ISI Ranking

Reed M. Izatt's number in the ISI rankings is 68.

Scientific work

Izatt and his colleagues, James J. Christensen and John L. Oscarson constructed and used a variety of novel high precision

calorimeters A calorimeter is an object used for calorimetry, or the process of measuring the heat of chemical reactions or physical changes as well as heat capacity. Differential scanning calorimeters, isothermal micro calorimeters, titration calorimeter ...

to study a number of host and guest chemical systems of both academic and commercial interest. Izatts thermodynamic results have been used in the development of macrocyclic and supramolecular chemistry, molecular recognition, heats of mixing,

nucleic acid Nucleic acids are biopolymers, macromolecules, essential to all known forms of life. They are composed of nucleotides, which are the monomers made of three components: a 5-carbon sugar, a phosphate group and a nitrogenous base. The two main cl ...

chemistry, metal

cyanide Cyanide is a naturally occurring, rapidly acting, toxic chemical that can exist in many different forms. In chemistry, a cyanide () is a chemical compound that contains a functional group. This group, known as the cyano group, consists of a ...

chemistry, chemical separations, amino acid microspecies formation, and high- temperature corrosion chemistry,

Macrocyclic chemistry

Izatt and Christensen made the first extensive thermodynamic study using titration calorimetry of the highly selective metal complexation properties of metal-cyclic polyether interactions. This work was followed by research correlating metal ion selectivity to macrocycle structure in a variety of

solvents A solvent (s) (from the Latin '' solvō'', "loosen, untie, solve") is a substance that dissolves a solute, resulting in a solution. A solvent is usually a liquid but can also be a solid, a gas, or a supercritical fluid. Water is a solvent for p ...

using a range of metal ions and

organic Organic may refer to: * Organic, of or relating to an organism, a living entity * Organic, of or relating to an anatomical organ Chemistry * Organic matter, matter that has come from a once-living organism, is capable of decay or is the product ...

amine cations. Using chiral macrocycles and chiral alkylammonium salts, Izatt and his colleagues were the first to establish host–guest chiral recognition in a given system by more than one experimental method (temperature-dependent ¹HNMR spectroscopy in CD₂Cl₂, titration calorimetry in methanol, and selective crystallization) and to report K, ΔH, and ΔS values for the interactions, thus quantitating the reactions. Subsequent x- ray

crystallographic Crystallography is the experimental science of determining the arrangement of atoms in crystalline solids. Crystallography is a fundamental subject in the fields of materials science and solid-state physics (condensed matter physics). The word ...

results provided a structural basis for the recognition. Use of fluorophores appended to macrocycles provides advantages over other techniques for selective and sensitive metal ion detection. Izatt demonstrated that certain 8-¬hydroxyquinoline derivatives attached to diazamacrocycles elicit a strong fluorescent response when complexed to selected closed-shell metal ions. That is, Hg²⁺, Cd²⁺, Zn²⁺ and Mg²⁺. The novelty of this work lies in the high-fluorescent selectivity these

ligands In coordination chemistry, a ligand is an ion or molecule (functional group) that binds to a central metal atom to form a coordination complex. The bonding with the metal generally involves formal donation of one or more of the ligand's electro ...

possess for the indicated metal ions in the presence of competing metal ions. The work presents the possibility of producing novel supported sensor systems capable of metal detection. In principle, detection limits could be well below parts per trillion (ng/mL). This level of detection coupled with the high metal ion selectivity imparted by the macrocyclic ligand could make these systems valuable in detecting target metal ions in environmental chemistry and as a means of continuously monitoring target metal ion concentrations in industrial streams.

Separations chemistry

Izatt and his colleagues were the first to attach macrocycles to a solid matrix and make highly selective metal separations. This achievement resulted in the establishment of IBC Advanced Technologies, Inc. (IBC) which commercialized the discovery.

Legacy

Commercialization of research results

In the 1960s, Izatt and Christensen developed high-precision titration

capable of simultaneously measuring equilibrium constants and heats for

chemical reactions A chemical reaction is a process that leads to the chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the positions of electrons in the forming and breaking ...

rapidly and with precision. These

were marketed worldwide through TRONAC, a chemical instrumentation company located in

. This calorimeter line was later acquired by TA Instruments. In 1988, IBC Advanced Technologies, Incorporated (IBC) was founded in Provo, Utah by Izatt, Bradshaw and Christensen. IBC commercialized work in chemical separations using an environmentally safe process based on molecular recognition technology (MRT).Izatt, N. et al ''Contributions of Professor Reed M. Izatt to molecular recognition technology: from laboratory to commercial application.'' Ind. Eng. Chem. Res. 2000 Vol 39 pp3405-3411 The MRT process enables the rapid and highly selective separation of metals from solutions even in the presence of complex matrices consisting of high concentrations of competing metals and high concentrations of acids or bases. This technology is important in the purification of precious, rare, and base metals during the refining process as well as in the recovery of these metals from spent products such as catalysts and electronics. IBC's MRT products are effective in the remediation of radioactive waste, selectively separating and concentrating radionuclides such as Cs, Sr, Tc, and Ra.Goken, G. et al ''Metal ion separations using superLig or anaLig materials encased in empore cartridges and disks.'' 1999.Bond A. et al ''Metal ion separation and preconcentration; progress and opportunities.'' ACS Symposium Series 716, American Chemical Society, Washington, D.C., Chapter 17, pp251-259. In addition, IBC's MRT products are used for analytical sample preparation and determination of metals, including toxic metals and radionuclides.

International macrocyclic chemistry symposia

In 1977, Izatt and Christensen organized the first ''

Symposium In ancient Greece, the symposium ( grc-gre, συμπόσιον ''symposion'' or ''symposio'', from συμπίνειν ''sympinein'', "to drink together") was a part of a banquet that took place after the meal, when drinking for pleasure was acc ...

on Macrocylic Compounds'' in Provo, Utah. In 1985, this and related symposia were incorporated into the ''International Symposium on Macrocyclic Chemistry (ISMC)''.Izatt, R. et al. ''Contributions of the International Symposium on Macrocyclic Chemistry to the development of macrocyclic chemistry.'' in ''Macrocyclic Chemistry: Current and Future Perspectives.'' Gloe, K., (ed.) Springer, Dordrecht, The Netherlands, 2005, Chapter 1, pp. 1-14. In 2006, ISMC was expanded to include supramolecular chemistry and the name was changed to International Symposium on Macrocyclic and Supramolecular Chemistry (ISMSC).

International Izatt-Christensen award

Since 1991, the International Izatt-Christensen award is presented annually at the ISMC (until 2005) and ISMSC (from 2006) meetings. The award recognizes excellence in macrocyclic and supramolecular chemistry and is regarded as the highest international award in these areas. Recipients include: *

Jean-Pierre Sauvage Jean-Pierre Sauvage (; born 21 October 1944) is a French coordination chemist working at Strasbourg University. He graduated from the National School of Chemistry of Strasbourg (now known as ECPM Strasbourg), in 1967. He has specialized in ...

(1991) * Eiichi Kimura (1992) *

J. Fraser Stoddart Sir James Fraser Stoddart (born 24 May 1942) is a British-American chemist who is Board of Trustees Professor of Chemistry and head of the Stoddart Mechanostereochemistry Group in the Department of Chemistry at Northwestern University in ...

(1993) * Daryle H. Busch (1994) * David N. Reinhoudt (1995) * George W. Gokel (1996) * Alan M. Sargeson (1997) *

Seiji Shinkai is a Japanese chemist and professor of Kyushu University, and emeritus professor. Early life Shinkai was born in Fukuoka prefecture, Japan, in 1944. He completed his B.S. in 1967 and Ph.D. in 1972 from Kyushu University. Career and research ...

(1998) * Fritz Vögtle (1999) * Jerry L. Atwood (2000) *

Jonathan Sessler Jonathan Sessler (born 20 May 1956 in Urbana, Illinois) is a professor of chemistry at The University of Texas at Austin. He is notable for his pioneering work on expanded porphyrins and their applications to biology and medicine. He is a co-f ...

(2001) * David Gutsche (2002) *

Jeremy Sanders Jeremy Keith Morris Sanders (born 3 May 1948) is a British chemist and Emeritus Professor in the Department of Chemistry at the University of Cambridge. He is also Editor-in-Chief of Royal Society Open Science. He is known for his contributio ...

(2003) * Makoto Fujita (2004) *

Kenneth Raymond Kenneth Norman Raymond (born January 7, 1942) is a bioinorganic and coordination chemist. He is Chancellor's Professor of Chemistry at University of California, Berkeley, Professor of the Graduate School, the Director of the Seaborg Center in t ...

(2005) * Roeland Nolte (2006) * David Leigh (2007) * Akira Harada (2008) *

Omar M. Yaghi Omar M. Yaghi ( ar, عمر مونّس ياغي; born February 9, 1965) is the James and Neeltje Tretter Chair Professor of Chemistry at the University of California, Berkeley, the Founding Director of the Berkeley Global Science Institute, and a ...

(2009) * Luigi Fabbrizzi (2010) *

Andrew D. Hamilton Andrew David Hamilton (born 3 November 1952) is a British American chemist and academic who is the 16th and current President of New York University. From 2009 to 2015, he served as the Vice-Chancellor of the University of Oxford. Before leadi ...

(2011) * Kimoon Kim (2012) *

Eric V. Anslyn Eric V. Anslyn (born June 9, 1960, Santa Monica, California) is an American chemist , University Distinguished Teaching Professor, and Welch Regents Chair in Chemistry at the University of Texas at Austin. He previously held the Norman Hackerma ...

(2013) * Mir Wais Hosseini (2014) * Paul D. Beer (2015) * Hanadi Sleiman (2016) * Harry L. Anderson (2017) *

Philip A. Gale Philip Alan Gale (born 1969) is a British chemist, Deputy Dean of Science and Professor of Chemistry at the Faculty of Science, University of Technology Sydney. He is notable for his work on the supramolecular chemistry of anions. Gale was bor ...

(2018) * Luisa De Cola (2019) * Mitsuhiko Shionoya (2020) * Ivan Huc (2021)

Endowed Reed M. Izatt and James J. Christensen awards

In 2007, Izatt created an endowment at Brigham Young University to reward faculty excellence in research in the Department of Chemistry and Biochemistry and in the Department of Chemical Engineering, and to provide funds to invite an eminent scientist or engineer from the worldwide community to present two lectures to the combined Departments of Chemistry and Biochemistry, and Chemical Engineering, one more universal in nature for the general public and the second more technical in nature for faculty and students. Recipients of the Reed M. Izatt Faculty Excellence in Research Award in Chemistry include: * Milton L. Lee (2008) * Paul B. Savage (2010) * Adam T. Woolley (2012) The Reed M. Izatt and James J. Christensen lecturers include: *

(15–16 November 2007) * Gabor A. Somorjai (21–22 January 2009) *

George M. Whitesides George McClelland Whitesides (born August 3, 1939) is an American chemist and professor of chemistry at Harvard University. He is best known for his work in the areas of nuclear magnetic resonance spectroscopy, organometallic chemistry, molecula ...

(3–4 November 2009) *

Robert Byron Bird Robert Byron Bird (February 5, 1924 – November 13, 2020) was an American chemical engineer and professor emeritus in the Department of Chemical Engineering at the University of Wisconsin-Madison. He was known for his research in transport pheno ...

(17–18 November 2010) *

Richard N. Zare Richard Neil Zare (born November 19, 1939, in Cleveland, Ohio) is the Marguerite Blake Wilbur Professor in Natural Science and a Professor of Chemistry at Stanford University. Throughout his career, Zare has made a considerable impact in physic ...

(7–8 February 2012) *

Robert Langer Robert Samuel Langer Jr. FREng (born August 29, 1948) is an American chemical engineer, scientist, entrepreneur, inventor and one of the twelve Institute Professors at the Massachusetts Institute of Technology. He was formerly the Germeshau ...

(6–7 February 2013) * Mario Capecchi (23–24 January 2014) * Alexis T. Bell (19 March 2015) *

R. Graham Cooks Robert Graham Cooks is the Henry Bohn Hass Distinguished Professor of Chemistry in the Aston Laboratories for Mass Spectrometry at Purdue University. He is an ISI Highly Cited Chemist, with over 1,000 publications and an H-index of 134. Educatio ...

(20-21 March 2017) * Franklin Orr (19-20 October 2017) *

Geraldine L. Richmond Geraldine Lee Richmond (born January 17, 1953 in Salina, Kansas) is an American chemist and Physical chemistry, physical chemist who is serving as the Under Secretary of Energy for Science in the US Department of Energy. Richmond was confirmed to ...

(26-27 February 2019) *

Thomas F. Edgar Thomas Flynn Edgar (born April 17, 1945) is an American chemical engineer. He was elected a member of the National Academy of Engineering in 2014 for contributions to mathematical modeling, optimization, and automatic control of chemical an ...

(19-20 February 2020)

References

External links