Phase Genomics is an American biotechnology company based in Seattle, Washington. The company develops proximity ligation kits and Hi-C sequencing technology used to analyze chromosomes. Phase Genomics sells proximity ligation kits, scientific services, and computational analyses.

History

The company was founded by Ivan Liachko and Shawn Sullivan in 2015. It was originally housed in the CoMotion biotech

incubator An incubator is anything that performs or facilitates various forms of incubation, and may refer to: Biology and medicine * Incubator (culture), a device used to grow and maintain microbiological cultures or cell cultures * Incubator (egg), a de ...

at University of Washington before relocating to a separate facility. It develops proximity ligation kits and Hi-C sequencing technology used to analyze chromosomes. The company sells proximity ligation kits, scientific services, and computational analyses.

Research

Phase Genomics developed a library preparation kit for the Hi-C sequencing method previously developed by researchers

Job Dekker Job Dekker is a Dutch biologist. Dekker is a professor in the Department of Systems Biology, and the Department of Biochemistry and Molecular Biotechnology at the University of Massachusetts Chan Medical School and an Investigator at the Howard Hu ...

and Eric Lander. The kits are used to study the architecture of genomes. In 2018, Phase Genomics received a $1.5 million

SBIR The Small Business Innovation Research (or SBIR) program is a U.S. government funding program, coordinated by the Small Business Administration, intended to help certain small businesses conduct research and development (R&D). Funding takes the ...

grant from the National Institute of Allergy and Infectious Diseases (NIAID) to research antimicrobial resistance using Hi-C technology. In January 2020, it was awarded an additional $1.5 million from NIAID for phase 2 SBIR funding. In 2019, Phase Genomics received $200,000 from the

Bill & Melinda Gates Foundation The Bill & Melinda Gates Foundation (BMGF), a merging of the William H. Gates Foundation and the Gates Learning Foundation, is an American private foundation founded by Bill Gates and Melinda French Gates. Based in Seattle, Washington, it was l ...

to improve computational methods of extracting

genomic Genomics is an interdisciplinary field of biology focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, three-dim ...

data in microbiome samples. Later in 2019, the company was awarded $325,000 from the

U.S. Department of Energy The United States Department of Energy (DOE) is an executive department of the U.S. federal government that oversees U.S. national energy policy and manages the research and development of nuclear power and nuclear weapons in the United States. ...

to research algae biofuels using proximity litigation technology for metagenome assembly. In 2020, Phase Genomics received 2 grants totaling $3.9 million from the National Human Genome Research Institute and the Eunice Kennedy Shriver National Institute of Child Health and Human Development. The 3-year grants fund research on

chromosomal abnormalities A chromosomal abnormality, chromosomal anomaly, chromosomal aberration, chromosomal mutation, or chromosomal disorder, is a missing, extra, or irregular portion of chromosomal DNA. These can occur in the form of numerical abnormalities, where ther ...

causing cancer, infertility, and reproductive issues. In June 2021, the company released a platform for discovering new viruses in microbiome samples.

References

External links

* {{Authority control Biotechnology companies established in 2015 Genomics companies 2015 establishments in Washington (state) Companies based in Seattle Biotechnology companies of the United States