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Job Dekker
Job Dekker is a Dutch biologist. Dekker is a professor in the Department of Systems Biology, and the Department of Biochemistry and Molecular Biotechnology at the University of Massachusetts Chan Medical School and an Investigator at the Howard Hughes Medical Institute. Dekker studied molecular genetics and biochemistry as an undergraduate at Utrecht University, where he also obtained a Ph.D. in Physiological Chemistry in 1997. During his postdoctoral studies in Nancy Kleckner’s lab at Harvard University, Dekker developed a method, called chromosome conformation capture, for identifying a matrix of the pair-wise interactions between different sites of chromatin and inferring the spatial folding of chromosomes from this information. Dekker's work has led to insights into how genomes are folded in three dimensions, the mechanisms that cells employ to fold chromosomes, and how chromosome folding contributes to gene regulation and chromosome segregation. Awarded the Edward Novits ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dutch People
The Dutch (Dutch: ) are an ethnic group and nation native to the Netherlands. They share a common history and culture and speak the Dutch language. Dutch people and their descendants are found in migrant communities worldwide, notably in Aruba, Suriname, Guyana, Curaçao, Argentina, Brazil, Canada,Based on Statistics Canada, Canada 2001 Censusbr>Linkto Canadian statistics. Australia, South Africa, New Zealand and the United States.According tFactfinder.census.gov The Low Countries were situated around the border of France and the Holy Roman Empire, forming a part of their respective peripheries and the various territories of which they consisted had become virtually autonomous by the 13th century. Under the Habsburgs, the Netherlands were organised into a single administrative unit, and in the 16th and 17th centuries the Northern Netherlands gained independence from Spain as the Dutch Republic. The high degree of urbanization characteristic of Dutch society was attained at a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene Regulation
Regulation of gene expression, or gene regulation, includes a wide range of mechanisms that are used by cells to increase or decrease the production of specific gene products (protein or RNA). Sophisticated programs of gene expression are widely observed in biology, for example to trigger developmental pathways, respond to environmental stimuli, or adapt to new food sources. Virtually any step of gene expression can be modulated, from transcriptional initiation, to RNA processing, and to the post-translational modification of a protein. Often, one gene regulator controls another, and so on, in a gene regulatory network. Gene regulation is essential for viruses, prokaryotes and eukaryotes as it increases the versatility and adaptability of an organism by allowing the cell to express protein when needed. Although as early as 1951, Barbara McClintock showed interaction between two genetic loci, Activator (''Ac'') and Dissociator (''Ds''), in the color formation of maize seeds, th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Year Of Birth Missing (living People)
A year or annus is the orbital period of a planetary body, for example, the Earth, moving in its orbit around the Sun. Due to the Earth's axial tilt, the course of a year sees the passing of the seasons, marked by change in weather, the hours of daylight, and, consequently, vegetation and soil fertility. In temperate and subpolar regions around the planet, four seasons are generally recognized: spring, summer, autumn and winter. In tropical and subtropical regions, several geographical sectors do not present defined seasons; but in the seasonal tropics, the annual wet and dry seasons are recognized and tracked. A calendar year is an approximation of the number of days of the Earth's orbital period, as counted in a given calendar. The Gregorian calendar, or modern calendar, presents its calendar year to be either a common year of 365 days or a leap year of 366 days, as do the Julian calendars. For the Gregorian calendar, the average length of the calendar year (the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
UMass Chan Medical School Faculty
The University of Massachusetts is the five-campus public university system and the only public research system in the Commonwealth of Massachusetts. The university system includes five campuses (Amherst, Boston, Dartmouth, Lowell, and a medical school in Worcester), a satellite campus in Springfield and also 25 campuses throughout California and Washington with the University of Massachusetts Global. The system administration is in Boston and Shrewsbury and is accredited by the New England Association of Schools and Colleges and across its campuses enrolls 75,065 students. Campuses The University of Massachusetts Amherst is the flagship and largest school in the UMass system. It was also the first one established, dating back to 1863, when it was founded as the Massachusetts Agricultural College. The University of Massachusetts Chan Medical School was founded in 1962, and is located in Worcester. The University of Massachusetts Boston, originally established in 1964, was mer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Utrecht University Alumni
Utrecht ( , , ) is the fourth-largest city and a municipality of the Netherlands, capital and most populous city of the province of Utrecht. It is located in the eastern corner of the Randstad conurbation, in the very centre of mainland Netherlands, about 35 km south east of the capital Amsterdam and 45 km north east of Rotterdam. It has a population of 361,966 as of 1 December 2021. Utrecht's ancient city centre features many buildings and structures, several dating as far back as the High Middle Ages. It has been the religious centre of the Netherlands since the 8th century. It was the most important city in the Netherlands until the Dutch Golden Age, when it was surpassed by Amsterdam as the country's cultural centre and most populous city. Utrecht is home to Utrecht University, the largest university in the Netherlands, as well as several other institutions of higher education. Due to its central position within the country, it is an important hub for both rail and road t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dutch Biochemists
Dutch commonly refers to: * Something of, from, or related to the Netherlands * Dutch people () * Dutch language () Dutch may also refer to: Places * Dutch, West Virginia, a community in the United States * Pennsylvania Dutch Country People Ethnic groups * Germanic peoples, the original meaning of the term ''Dutch'' in English ** Pennsylvania Dutch, a group of early Germanic immigrants to Pennsylvania *Dutch people, the Germanic group native to the Netherlands Specific people * Dutch (nickname), a list of people * Johnny Dutch (born 1989), American hurdler * Dutch Schultz (1902–1935), American mobster born Arthur Simon Flegenheimer * Dutch Mantel, ring name of American retired professional wrestler Wayne Maurice Keown (born 1949) * Dutch Savage, ring name of professional wrestler and promoter Frank Stewart (1935–2013) Arts, entertainment, and media Fictional characters * Dutch (''Black Lagoon''), an African-American character from the Japanese manga and anime ''Black L ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Academy Of Medicine
The National Academy of Medicine (NAM), formerly called the Institute of Medicine (IoM) until 2015, is an American nonprofit, non-governmental organization. The National Academy of Medicine is a part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Sciences (NAS), National Academy of Engineering (NAE), and the National Research Council (NRC). The National Academy of Medicine provides national and international advice on issues relating to health, medicine, health policy, and biomedical science. It aims to provide unbiased, evidence-based, and authoritative information and advice concerning health and science policy to policy-makers, professionals, leaders in every sector of society, and the public at large. Operating outside the framework of the U.S. federal government, it relies on a volunteer workforce of scientists and other experts, operating under a formal peer-review system. As a national academy, the organization ann ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Academy Of Sciences
The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the National Academy of Medicine (NAM). As a national academy, new members of the organization are elected annually by current members, based on their distinguished and continuing achievements in original research. Election to the National Academy is one of the highest honors in the scientific field. Members of the National Academy of Sciences serve '' pro bono'' as "advisers to the nation" on science, engineering, and medicine. The group holds a congressional charter under Title 36 of the United States Code. Founded in 1863 as a result of an Act of Congress that was approved by Abraham Lincoln, the NAS is charged with "providing independent, objective advice to the nation on matters related to science and technology. ... to provide scien ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biochemical Society
The Biochemical Society is a learned society in the United Kingdom in the field of biochemistry, including all the cellular and molecular biosciences. Structure It currently has around 7000 members, two-thirds in the UK. It is affiliated with the European body, Federation of European Biochemical Societies (FEBS). The Society's current President (2016) is Sir David Baulcombe. The Society's headquarters are in London. History The society was founded in 1911 by Benjamin Moore, W.D. Halliburton and others, under the name of the Biochemical Club. It acquired the existing ''Biochemical Journal'' in 1912. The society name changed to the Biochemical Society in 1913. In 2005, the headquarters of the society moved from Portland Place to purpose-built offices in Holborn. In 2009, the headquarters moved again to Charles Darwin House, near Gray's Inn Road. Past presidents include Professor Ron Laskey, Sir Philip Cohen, and Sir Tom Blundell. Awards The society makes a number of merit a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Edward Novitski Prize
The Edward Novitski Prize is awarded by the Genetics Society of America (GSA) to recognize an extraordinary level of creativity and intellectual ingenuity in solving significant problems in genetics research. Named in honor of Drosophila geneticist Edward Novitski (1918-2006), the award recognizes scientific achievement that stands out from the body of innovative work, that is deeply impressive to creative masters in the field, and that solves a difficult problem in genetics. It recognizes the beautiful and intellectually ingenious experimental design and execution involved in genetics scientific discovery. The prize, established by the Novitski family, includes an engraved medal. Award recipients Source: * 2008 Thomas J. Silhavy * 2009 Rodney J. Rothstein and Kent Golic * 2010 * 2011 Abby F. Dernburg * 2012 Dana Carroll * 2013 Jonathan K. Pritchard * 2014 Charles Boone * 2015 Sue Biggins * 2016 Leonid Kruglyak, HHMI and University of California, Los Angeles * 2017 Jon ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chromosome Segregation
Chromosome segregation is the process in eukaryotes by which two sister chromatids formed as a consequence of DNA replication, or paired homologous chromosomes, separate from each other and migrate to opposite poles of the nucleus. This segregation process occurs during both mitosis and meiosis. Chromosome segregation also occurs in prokaryotes. However, in contrast to eukaryotic chromosome segregation, replication and segregation are not temporally separated. Instead segregation occurs progressively following replication. Mitotic chromatid segregation During mitosis chromosome segregation occurs routinely as a step in cell division (see mitosis diagram). As indicated in the mitosis diagram, mitosis is preceded by a round of DNA replication, so that each chromosome forms two copies called chromatids. These chromatids separate to opposite poles, a process facilitated by a protein complex referred to as cohesin. Upon proper segregation, a complete set of chromatids ends up in eac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chromosomes
A chromosome is a long DNA molecule with part or all of the genetic material of an organism. In most chromosomes the very long thin DNA fibers are coated with packaging proteins; in eukaryotic cells the most important of these proteins are the histones. These proteins, aided by chaperone proteins, bind to and condense the DNA molecule to maintain its integrity. These chromosomes display a complex three-dimensional structure, which plays a significant role in transcriptional regulation. Chromosomes are normally visible under a light microscope only during the metaphase of cell division (where all chromosomes are aligned in the center of the cell in their condensed form). Before this happens, each chromosome is duplicated (S phase), and both copies are joined by a centromere, resulting either in an X-shaped structure (pictured above), if the centromere is located equatorially, or a two-arm structure, if the centromere is located distally. The joined copies are now called sis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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