Isometamidium chloride is a

triazene Triazene is an unsaturated inorganic compound having the chemical formula N3 H3. It has one double bond and is the second-simplest member of the azene class of hydronitrogen compounds, after diimide. Triazenes are a class of organic compounds ...

trypanocidal agent A trypanocidal agent is an antiprotozoal agent that acts upon trypanosome parasites. Examples include: * Aminoquinuride * benzonidazole * blasticidin S * DAPI * diminazene * diminazene aceturate * eflornithine * ethidium * isometamidium chlor ...

used in veterinary medicine. It consists of a single

Ethidium bromide Ethidium bromide (or homidium bromide, chloride salt homidium chloride) is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis. It i ...

like subunit linked to a fragment of the

diminazene Diminazene (INN; also known as diminazen) is an anti-infective medication for animals that is sold under a variety of brand names. It is effective against certain protozoa such as ''Babesia'', ''Trypanosoma'', and '' Cytauxzoon''. The drug may a ...

molecule.

Resistance

The

Gibe River The Gibe River (also Great Gibe River) is by far the largest tributary of the Omo River in Ethiopia and typically flowing south-southeast. The confluence of the large Gibe River at with the smaller Wabe River forms the even larger Omo River. Cons ...

Valley in southwest

Ethiopia Ethiopia, , om, Itiyoophiyaa, so, Itoobiya, ti, ኢትዮጵያ, Ítiyop'iya, aa, Itiyoppiya officially the Federal Democratic Republic of Ethiopia, is a landlocked country in the Horn of Africa. It shares borders with Eritrea to the ...

showed universal resistance between July 1989 and February 1993. This likely indicates a permanent loss of function in this area against the tested target, '' T. congolense'' isolated from

Boran Boran (also spelled Buran, Middle Persian: ; New Persian: پوران‌دخت, ''Pūrāndokht'') was Sasanian queen (or '' banbishn'') of Iran from 630 to 632, with an interruption of some months. She was the daughter of king (or ''shah'') Kho ...

cattle.

References

Amidines Antiparasitic agents Quaternary ammonium compounds {{antiinfective-drug-stub