Irène Landau
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Irène Landau is a French
parasitologist Parasitology is the study of parasites, their hosts, and the relationship between them. As a biological discipline, the scope of parasitology is not determined by the organism or environment in question but by their way of life. This means it f ...
and
professor emeritus ''Emeritus'' (; female: ''emerita'') is an adjective used to designate a retired chair, professor, pastor, bishop, pope, director, president, prime minister, rabbi, emperor, or other person who has been "permitted to retain as an honorary title ...
at the
National Museum of Natural History, France The French National Museum of Natural History, known in French as the ' (abbreviation MNHN), is the national natural history museum of France and a ' of higher education part of Sorbonne Universities. The main museum, with four galleries, is loc ...
(MNHN) and
Centre national de la recherche scientifique The French National Centre for Scientific Research (french: link=no, Centre national de la recherche scientifique, CNRS) is the French state research organisation and is the largest fundamental science Basic research, also called pure research o ...
. Landau initially studied medicine, obtaining her medical qualifications in
Paris Paris () is the capital and most populous city of France, with an estimated population of 2,165,423 residents in 2019 in an area of more than 105 km² (41 sq mi), making it the 30th most densely populated city in the world in 2020. S ...
in 1958 and a certificate in tropical medicine in 1963. She changed to focus on parasitology research, joining the lab of Lucien Brumpt in 1964 as a research assistant, and a year later relocating to
Alain Chabaud Alain Chabaud (13 March 1923 – 11 March 2013) was a French parasitologist, mainly a specialist of nematodes and sporozoa. He was the Director of the Laboratoire de Zoologie (Vers) in the Muséum National d'Histoire Naturelle in Paris from 1960 to ...
's group at the MNHN. She was promoted in 1966 to senior lecturer and made group head of studying the ''Plasmodium'' genus. She briefly worked in London in the 1960s in the group of
Cyril Garnham Percy Cyril Claude Garnham Companion of the Order of St Michael and St George, CMG Fellow of the Royal Society, FRS (15 January 1901 – 25 December 1994), was a British Biology, biologist and parasitologist. On his 90th birthday, he was calle ...
at the
London School of Hygiene & Tropical Medicine The London School of Hygiene and Tropical Medicine (LSHTM) is a public research university in Bloomsbury, central London, and a member institution of the University of London that specialises in public health and tropical medicine. The inst ...
, where she met and begun collaborating with
Wallace Peters Wallace Peters (April 1, 1924 – December 2018) was a British entomologist and parasitologist. He is noted for his work on malaria and won the Joseph Augustin LePrince Medal for outstanding work in the field of malariology in 1994. He also won Ge ...
and Robert Killick-Kendrick. During a research trip to the
Central African Republic The Central African Republic (CAR; ; , RCA; , or , ) is a landlocked country in Central Africa. It is bordered by Chad to the north, Sudan to the northeast, South Sudan to the southeast, the DR Congo to the south, the Republic of th ...
in 1964/5 Landau isolated and described the rodent
malaria Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. S ...
parasite ''
Plasmodium chabaudi ''Plasmodium chabaudi'' is a parasite of the genus ''Plasmodium'' subgenus ''Vinckeia''. As in all ''Plasmodium'' species, ''P. chabaudi'' has both vertebrate and insect hosts. The vertebrate hosts for this parasite are rodents. Taxonomy This ...
'' (naming it after her supervisor) from local ''
Thamnomys rutilans The shining thicket rat (''Grammomys poensis'') is a species of rodent in the family Muridae. Distribution and habitat It is found in Angola, Burundi, Cameroon, Central African Republic, Republic of the Congo, Democratic Republic of the Congo ...
'' thicket rats. She brought these samples with her to London, and together with Killick-Kendrich they isolated and identified another new rodent malaria species. The species was similar to ''
Plasmodium berghei ''Plasmodium berghei'' is a species in the genus ''Plasmodium'' subgenus ''Vinckeia''. It is a protozoan parasite that causes malaria in certain rodents. Originally, isolated from thicket rats in Central Africa, ''P. berghei'' is one of four '' ...
'', and it was named ''
Plasmodium yoelii ''Plasmodium yoelii'' is a parasite of the genus ''Plasmodium'' subgenus ''Vinckeia''. As in all ''Plasmodium'' species, ''P. yoelii'' has both vertebrate and insect Insects (from Latin ') are pancrustacean hexapod invertebrates of the c ...
'' in homage to the malarial researcher Meir Yoeli. To this day both species are used extensively in malaria research. Peters, Landau and Killick-Kendrick styled themselves as the 'plasmodiacs'. When visiting Elizabeth U Canning at
Silwood Park Silwood Park is the rural campus of Imperial College London, England. It is situated near the village of Sunninghill, near Ascot in Berkshire. Since 1986, there have been major developments on the site with four new college buildings. Adjacent ...
in the 1970s she snuck a royal python over to England on her flight. The snake was reportedly kept as a pet in the department for many years. Also in the 1970s, Landau visited the Wellcome Parasitology Institute in
Belém Belém (; Portuguese for Bethlehem; initially called Nossa Senhora de Belém do Grão-Pará, in English Our Lady of Bethlehem of Great Pará) often called Belém of Pará, is a Brazilian city, capital and largest city of the state of Pará in t ...
to study the recently discovered
Saurocytozoon ''Saurocytozoon'' is a genus of parasitic alveolates. They infect reptiles and are thought to be transmitted by mosquitoes. Only two species have been described to date. Their relationship with the other members of this order is not presently cle ...
s with
Ralph Lainson Ralph Lainson OBE, FRS (21 February 1927 – 5 May 2015) was a British parasitologist who studied leishmaniasis in Brazil. He was the first to publish a record of Chagas disease. Life Lainson was born in Upper Beeding, Sussex on 21 February 1927 ...
. It was after the respected British parasitologist that Landau later named the Lankesterellidae genus '' Lainsonia.'' She submitted her PhD thesis in 1972, entitled La diversité des mecanismes assurant la perennite de l'infection chez les sporozoaires coccidiomorphes coccidiomorphic sporozoites">Coccidia.html" ;"title="he variety of mechanisms that ensure the persistence of infection in Coccidia">coccidiomorphic sporozoites''. She advanced to co-director of the lab in 1987 before becoming full director of the lab of protozoology and comparative parasitology in 1989. In 1994 she was promoted to a full professor. Her and Chabaud were awarded the 1999 Émile Brumpt prize for their contributions to parasitology. Landau has continued to work on Apicomplexa parasites into the present day. She recently published (in collaboration with Francisco J. Ayala, Gregory Karadjian and Linda Duval) a description of the jumbled
mitochondrial genome Mitochondrial DNA (mtDNA or mDNA) is the DNA located in mitochondria, cellular organelles within eukaryotic cells that convert chemical energy from food into a form that cells can use, such as adenosine triphosphate (ATP). Mitochondrial D ...
s of ''
Nycteria ''Nycteria'' is a genus of protozoan parasites that belong to the phylum Apicomplexa. It is composed of vector-borne haemosporidian parasites that infect a wide range of mammals such as primates, rodents and bats. Its vertebrate hosts are bats. ...
'' parasites (which infect '' Nycteridae'' bats), explaining why ''
cytochrome b Cytochrome b within both molecular and cell biology, is a protein found in the mitochondria of eukaryotic cells. It functions as part of the electron transport chain and is the main subunit of transmembrane cytochrome bc1 and b6f complexes. F ...
'' sequencing of the parasites has been unsuccessful.


References

{{DEFAULTSORT:Landau, Irène French parasitologists French National Centre for Scientific Research scientists French women biologists National Museum of Natural History (France) people Malariologists