InterMine is an
open source
Open source is source code that is made freely available for possible modification and redistribution. Products include permission to use the source code, design documents, or content of the product. The open-source model is a decentralized sof ...
data warehouse system, licensed under the
LGPL 2.1. InterMine is used to create
databases of biological data accessed by sophisticated web query tools. InterMine can be used to create databases from a single data set or can integrate multiple sources of data. Support is provided for several common biological formats and there is a framework for adding other data. InterMine includes a user-friendly web interface that works 'out of the box' and can be easily customised.
InterMine makes it easy to integrate multiple data sources into a single data warehouse. It has a core data model based on the
sequence ontology
The Sequence Ontology (SO) is an ontology
In metaphysics, ontology is the philosophical study of being, as well as related concepts such as existence, becoming, and reality.
Ontology addresses questions like how entities are grouped int ...
and supports several biological data formats, allowing sysadmins to configure which organisms or data files are required. It is easy to extend the data model and integrate other data, with a web service API, clients in seven different languages, and an
XML
Extensible Markup Language (XML) is a markup language and file format for storing, transmitting, and reconstructing arbitrary data. It defines a set of rules for encoding documents in a format that is both human-readable and machine-readable. T ...
format to help import custom data.
As an active open source project, InterMine maintains
developer mailing listand thoroug
developeran
user documentation
Supported data formats
*
Chado
The Japanese tea ceremony (known as or ) is a Japanese cultural activity involving the ceremonial preparation and presentation of , powdered green tea, the procedure of which is called . While in the West it is known as "tea ceremony", it is sel ...
*
GFF3
In bioinformatics, the general feature format (gene-finding format, generic feature format, GFF) is a file format used for describing genes and other features of DNA, RNA and protein sequences.
GFF Versions
The following versions of GFF exist:
...
*
FASTA
FASTA is a DNA and protein sequence alignment software package first described by David J. Lipman and William R. Pearson in 1985. Its legacy is the FASTA format which is now ubiquitous in bioinformatics.
History
The original FASTA program ...
*
GO & gene association files
*
UniProt
UniProt is a freely accessible database of protein sequence and functional information, many entries being derived from genome sequencing projects. It contains a large amount of information about the biological function of proteins derived from ...
XML
* PSI XML (protein interactions,
Protein Structure Initiative
The Protein Structure Initiative (PSI) was a USA based project that aimed at accelerating discovery in structural genomics and contribute to understanding biological function. Funded by the U.S. National Institute of General Medical Sciences (NIGMS ...
)
*
InParanoid orthologs
*
Ensembl
Ensembl genome database project is a scientific project at the European Bioinformatics Institute, which provides a centralized resource for geneticists, molecular biologists and other researchers studying the genomes of our own species and other v ...
Clients
Web clients allow users to access the data programatically with minimal effort, and are available fo
perlpythonrubyjavascriptJava an
R Data can also be queried via
native Android app
Web application
The InterMine web application allows creation of custom bioinformatics queries, includes template queries (web forms to run 'canned' queries). Users can upload and operate on lists of data. It is possible to configure/create widgets to analyse lists with graphs and enrichment statistics.
An admin user can publish new template queries, change report pages and create public lists at any time without any programming. Many aspects of the web app can be configured and branded.
Current projects (not exhaustive list)
An up-to-date list of projects can be viewed at th
InterMine Registry
*
Generic Model Organism Database
The Generic Model Organism Database (GMOD) project provides biological research communities with a toolkit of open-source software components for visualizing, annotating, managing, and storing biological data. The GMOD project is funded by the Unit ...
modENCODE
FlyMineHumanMineRatMineYeastMineTargetMineMitoMinerMouseMineZebrafishMineWormMineINDIGOThaleMineTargetMinePhytoMineMedicMineBovineMineHymenopteraMineSoyMineBeanMineChickpeaMineLegumeMinePeanutMineShaareWheat3BminePlanMineGrapeMineRepetDBXenMineCHOMine
References
{{Reflist
External links
InterMineDepartment of Genetics, University of CambridgeWellcome TrustInterMine API Documentation
Bioinformatics software
Biological databases
Data warehousing products
Genetics in the United Kingdom
Science and technology in Cambridgeshire
South Cambridgeshire District