The enzyme Inositol-polyphosphate 5-phosphatase (EC 3.1.3.56, systematic name 1D-''myo''-inositol-1,4,5-trisphosphate 5-phosphohydrolase; other names type I inositol-polyphosphate phosphatase, inositol trisphosphate phosphomonoesterase, InsP₃/Ins(1,3,4,5)P₄ 5-phosphatase, inosine triphosphatase, D-''myo''-inositol 1,4,5-triphosphate 5-phosphatase, D-''myo''-inositol 1,4,5-trisphosphate 5-phosphatase, L-''myo''-inositol 1,4,5-trisphosphate-monoesterase'', ''inositol phosphate 5-phosphomonoesterase, inositol-1,4,5-trisphosphate/1,3,4,5-tetrakisphosphate 5-phosphatase, Ins(1,4,5)P₃ 5-phosphataseD-''myo''-inositol(1,4,5)/(1,3,4,5)-polyphosphate 5-phosphatase, inositol 1,4,5-trisphosphate phosphatase, inositol polyphosphate-5-phosphatase, ''myo''-inositol-1,4,5-trisphosphate 5-phosphatase, inositol-1,4,5-trisphosphate 5-phosphatase) catalyses the following reaction : (1) D-''myo''-inositol 1,4,5-trisphosphate + H₂O

\rightleftharpoons

''myo''-inositol 1,4-bisphosphate +

phosphate In chemistry, a phosphate is an anion, salt, functional group or ester derived from a phosphoric acid. It most commonly means orthophosphate, a derivative of orthophosphoric acid . The phosphate or orthophosphate ion is derived from phospho ...

: (2) 1D-''myo''-inositol 1,3,4,5-tetrakisphosphate + H₂O

\rightleftharpoons

1D-''myo''-inositol 1,3,4-trisphosphate + phosphate One

mammalian Mammals () are a group of vertebrate animals constituting the class (biology), class Mammalia (), characterized by the presence of mammary glands which in Female#Mammalian female, females produce milk for feeding (nursing) their young, a ...

isoform A protein isoform, or "protein variant", is a member of a set of highly similar proteins that originate from a single gene or gene family and are the result of genetic differences. While many perform the same or similar biological roles, some isof ...

is known.

References

External links

* {{Portal bar, Biology, border=no EC 3.1.3