IQ motif and Sec7 domain 2 is a
protein that in humans is encoded by the ''IQSEC2''
gene.
Function
The IQSEC2 gene encodes a
guanine nucleotide exchange factor for the ARF family of
GTP-binding proteins (see for example
ARF1
ADP-ribosylation factor 1 is a protein that in humans is encoded by the ''ARF1'' gene.
Function
ADP-ribosylation factor 1 (ARF1) is a member of the human ARF gene family. The family members encode small guanine nucleotide-binding proteins that ...
).
Clinical significance
It is associated with
X-Linked mental retardation
X-linked intellectual disability refers to medical disorders associated with X-linked recessive inheritance that result in intellectual disability.
As with most X-linked disorders, males are more heavily affected than females. Females with one aff ...
1.
References
Further reading
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Human proteins
{{gene-X-stub