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was a Japanese doctor and medical scientist of the Meiji and Taishō periods. He is best known for publishing the first description of the disease that was later named
Hashimoto's thyroiditis Hashimoto's thyroiditis, also known as chronic lymphocytic thyroiditis and Hashimoto's disease, is an autoimmune disease in which the thyroid gland is gradually destroyed. Early on, symptoms may not be noticed. Over time, the thyroid may enlarg ...
.


Biography

Hashimoto was born on 5 May 1881, in the village of Iga-cho, Ayama-gun, in
Mie Prefecture is a prefecture of Japan located in the Kansai region of Honshu. Mie Prefecture has a population of 1,781,948 () and has a geographic area of . Mie Prefecture is bordered by Gifu Prefecture to the north, Shiga Prefecture and Kyoto Prefectur ...
as the third son of Kennosuke Hashimoto, a physician. Hashimoto's family traditionally served as physicians to the district's feudal lords for centuries. Hashimoto's grandfather, General Hashimoto, was the most famous physician in the prefecture in his time, after having studied Dutch medicine. Hashimoto began his primary education in 1886 and entered the in
Kyoto Kyoto (; Japanese: , ''Kyōto'' ), officially , is the capital city of Kyoto Prefecture in Japan. Located in the Kansai region on the island of Honshu, Kyoto forms a part of the Keihanshin metropolitan area along with Osaka and Kobe. , the c ...
, considered to be at the time a leading pre-university educational establishment. In 1903, he enrolled in Fukuoka Medical College in
Fukuoka is the sixth-largest city in Japan, the second-largest port city after Yokohama, and the capital city of Fukuoka Prefecture, Japan. The city is built along the shores of Hakata Bay, and has been a center of international commerce since anc ...
, a branch of the newly-established
Kyushu University , abbreviated to , is a Japanese national university located in Fukuoka, on the island of Kyushu. It was the 4th Imperial University in Japan, ranked as 4th in 2020 Times Higher Education Japan University Rankings, one of the top 10 Design ...
. He was amongst the first medical graduates when he graduated in 1907. He then entered the First Surgical Bureau and studied medicine under the direction of (1867–1945), the first Japanese neurosurgeon. While working on his M.D. thesis, he examined four histology samples from surgically excised thyroids and described his findings as 'struma lymphomatosa'. He published his findings in the German journal Archiv für Klinische Chirurgie as German was considered the
lingua franca A lingua franca (; ; for plurals see ), also known as a bridge language, common language, trade language, auxiliary language, vehicular language, or link language, is a language systematically used to make communication possible between groups ...
of academia during this time. Hashimoto also published two further papers on
erysipelas Erysipelas () is a relatively common bacterial infection of the superficial layer of the skin ( upper dermis), extending to the superficial lymphatic vessels within the skin, characterized by a raised, well-defined, tender, bright red rash, ...
and on penetrating
chest wall The thoracic wall or chest wall is the boundary of the thoracic cavity. Structure The bony skeletal part of the thoracic wall is the rib cage, and the rest is made up of muscle, skin, and fasciae. The chest wall has 10 layers, namely (from s ...
injuries. In 1912, Hashimoto traveled to
University of Göttingen The University of Göttingen, officially the Georg August University of Göttingen, (german: Georg-August-Universität Göttingen, known informally as Georgia Augusta) is a public research university in the city of Göttingen, Germany. Founded ...
in Germany to study pathology under the training of
Eduard Kaufmann Eduard Kaufmann (24 March 1860, Bonn – 15 December 1931, Göttingen) was a German physician. The disease Abderhalden–Kaufmann–Lignac syndrome is named for him. Career Kaufmann studied in Bonn and Berlin, and earned his doctorate from ...
, with particular emphasis on
tuberculosis Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, ...
of the urinary tract. In 1915, Hashimoto returned to Japan via England as the
First World War World War I (28 July 1914 11 November 1918), often abbreviated as WWI, was List of wars and anthropogenic disasters by death toll, one of the deadliest global conflicts in history. Belligerents included much of Europe, the Russian Empire, ...
was underway. In 1916, he came back to his hometown, Igamachi, and became the town doctor, setting up his own surgical clinic. As a surgeon and general practitioner, Hashimoto would frequently visit patients in their homes, often utilising a
rickshaw A rickshaw originally denoted a two- or three-wheeled passenger cart, now known as a pulled rickshaw, which is generally pulled by one person carrying one passenger. The first known use of the term was in 1879. Over time, cycle rickshaws (als ...
, regardless of distance. In critical patients, he would perform surgery at their homes with only trained nurses accompanying him. He was also known to not charge fees to his poor patients. During this time, Hashimoto was often seen studying medicine late in the evening and was regarded as a lifelong student. In December 1933, Hashimoto fell ill with
typhoid fever Typhoid fever, also known as typhoid, is a disease caused by '' Salmonella'' serotype Typhi bacteria. Symptoms vary from mild to severe, and usually begin six to 30 days after exposure. Often there is a gradual onset of a high fever over severa ...
and eventually died at home on 9 January 1934 at the age of 52.


Scientific activities

In 1912, he published a paper, ''Kōjōsen rinpa-setsu shushō-teki henka ni kansuru kenkyū hōkoku'' or ''Zur Kenntnis der lymphomatösen Veränderung der Schilddrüse (Struma lymphomatosa)'' or (Report on
lymph Lymph (from Latin, , meaning "water") is the fluid that flows through the lymphatic system, a system composed of lymph vessels (channels) and intervening lymph nodes whose function, like the venous system, is to return fluid from the tissues ...
omatous
goiter A goitre, or goiter, is a swelling in the neck resulting from an enlarged thyroid gland. A goitre can be associated with a thyroid that is not functioning properly. Worldwide, over 90% of goitre cases are caused by iodine deficiency. The term is ...
) in "Archiv für klinische Chirurgie", Berlin, 1912:97:219-248. Years later, this paper was evaluated by English and American researchers, and the disease it described was recognized as an independent illness. In American medical books, it was named
Hashimoto's thyroiditis Hashimoto's thyroiditis, also known as chronic lymphocytic thyroiditis and Hashimoto's disease, is an autoimmune disease in which the thyroid gland is gradually destroyed. Early on, symptoms may not be noticed. Over time, the thyroid may enlarg ...
.


Personal life

Hashimoto married Yoshiko Miyake, the daughter of a naval doctor who studied
Japanese literature Japanese literature throughout most of its history has been influenced by cultural contact with neighboring Asian literatures, most notably China and its literature. Early texts were often written in pure Classical Chinese or , a Chinese-Japanes ...
at the Nara' Women's Higher College for Education. The couple had 4 children; one daughter (Hanako) and three sons (Ken'ichi, Haruo, Kazuo). He was a devout
Buddhist Buddhism ( , ), also known as Buddha Dharma and Dharmavinaya (), is an Indian religion or philosophical tradition based on teachings attributed to the Buddha. It originated in northern India as a -movement in the 5th century BCE, and ...
and was head of the Buddhist association at
Kyushu University , abbreviated to , is a Japanese national university located in Fukuoka, on the island of Kyushu. It was the 4th Imperial University in Japan, ranked as 4th in 2020 Times Higher Education Japan University Rankings, one of the top 10 Design ...
during his time as a student. On holidays, he was known to frequent
Osaka is a designated city in the Kansai region of Honshu in Japan. It is the capital of and most populous city in Osaka Prefecture, and the third most populous city in Japan, following Special wards of Tokyo and Yokohama. With a population of ...
or
Kyoto Kyoto (; Japanese: , ''Kyōto'' ), officially , is the capital city of Kyoto Prefecture in Japan. Located in the Kansai region on the island of Honshu, Kyoto forms a part of the Keihanshin metropolitan area along with Osaka and Kobe. , the c ...
by train and particularly enjoyed
Kabuki is a classical form of Japanese dance- drama. Kabuki theatre is known for its heavily-stylised performances, the often-glamorous costumes worn by performers, and for the elaborate make-up worn by some of its performers. Kabuki is thought ...
theatre and foreign book-shopping.


Hashimoto Street

To honor his achievements,
Kyushu University , abbreviated to , is a Japanese national university located in Fukuoka, on the island of Kyushu. It was the 4th Imperial University in Japan, ranked as 4th in 2020 Times Higher Education Japan University Rankings, one of the top 10 Design ...
named a road on its
Maidashi is a district of Higashi-ku, Fukuoka, in Fukuoka Prefecture, Japan. It is divided into six ''chōme'', numbered 1 to 6, with a total population of 8,813 and 5,341 households (as of 31 August 2011). The postal code for addresses in Maidashi is ...
campus "Hashimoto Street".


References

{{DEFAULTSORT:Hashimoto, Hakaru 1881 births 1934 deaths 20th-century Japanese physicians Deaths from typhoid fever Japanese Buddhists Japanese endocrinologists Japanese pathologists Kyushu University alumni People from Mie Prefecture