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Howard Wilbur Jones, Jr. (December 30, 1910 – July 31, 2015) was an American gynecological surgeon and
in vitro fertilization In vitro fertilisation (IVF) is a process of fertilisation where an egg is combined with sperm in vitro ("in glass"). The process involves monitoring and stimulating an individual's ovulatory process, removing an ovum or ova (egg or eggs) ...
(IVF) specialist. Jones and his wife, Georgeanna Seegar Jones, were two of the earliest reproductive medicine specialists in the United States. They established the reproductive medicine center that was responsible for the birth of the first IVF baby in the U.S. He wrote articles on the
beginning of human personhood The beginning of human personhood is the moment when a human is first recognized as a person. There are differences of opinion as to the precise time when human personhood begins and the nature of that status. The issue arises in a number of fi ...
and testified before legislators on the same subject. He was one of the early physicians to perform sex reassignment surgeries. Jones was on the faculty at
Johns Hopkins School of Medicine The Johns Hopkins University School of Medicine (JHUSOM) is the medical school of Johns Hopkins University, a private research university in Baltimore, Maryland. Founded in 1893, the School of Medicine shares a campus with the Johns Hopkins Hospi ...
from the 1940s until his mandatory retirement from the institution in 1978. He and his wife moved to Virginia and were affiliated with
Eastern Virginia Medical School Eastern Virginia Medical School (EVMS) is a public medical school in Norfolk, Virginia. Founded by grassroots efforts in the Southeastern part of Virginia known as Hampton Roads, EVMS is not affiliated with an undergraduate institution and co ...
(EVMS). Jones retired in the 1990s, but he continued to write and spent time at EVMS until shortly before his death.


Early life

Jones was born in
Baltimore Baltimore ( , locally: or ) is the List of municipalities in Maryland, most populous city in the U.S. state of Maryland, fourth most populous city in the Mid-Atlantic (United States), Mid-Atlantic, and List of United States cities by popula ...
to Howard Wilbur Jones, Sr. and Edith Ruth Marling Jones on December 30, 1910. Even though he lived in the city, Jones was educated for a few years in a rural public school to avoid the city public school system. When Jones was a child, he went on house calls and hospital visits with his father, who was a physician. Jones's father died when he was 13 years old. Jones's mother moved him to a private school after the death of his father. He earned an undergraduate degree from
Amherst College Amherst College ( ) is a private liberal arts college in Amherst, Massachusetts. Founded in 1821 as an attempt to relocate Williams College by its then-president Zephaniah Swift Moore, Amherst is the third oldest institution of higher educatio ...
in 1931 and a medical degree from
Johns Hopkins School of Medicine The Johns Hopkins University School of Medicine (JHUSOM) is the medical school of Johns Hopkins University, a private research university in Baltimore, Maryland. Founded in 1893, the School of Medicine shares a campus with the Johns Hopkins Hospi ...
in 1935. Jones completed a residency in surgery and then joined the U.S. Army during
World War II World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the vast majority of the world's countries—including all of the great powers—forming two opposin ...
, leading an Auxiliary Surgical Group team in Patton's Third Army. After the war, Jones was invited to complete a second residency in gynecology.


Career

Jones and his wife joined the faculty at Johns Hopkins on a part-time basis in 1948. He was the initial treating physician of
Henrietta Lacks Henrietta Lacks (born Loretta Pleasant; August 1, 1920 – October 4, 1951) Note: Some sources report her birthday as August 2, 1920, vs. August 1, 1920. was an African-American woman whose cancer cells are the source of the HeLa cell line ...
when she presented to Johns Hopkins with cancer in 1951. Jones took a biopsy of Lacks's tumor and sent samples to his laboratory colleagues. The cells, later known as
HeLa cells HeLa (; also Hela or hela) is an immortalized cell line used in scientific research. It is the oldest and most commonly used human cell line. The line is derived from cervical cancer cells taken on February 8, 1951, named after Henrietta L ...
, grew at an astonishing rate in the lab and were shipped and sold to researchers for various purposes. Research with the cells helped to facilitate medical breakthroughs, including the vaccines for
polio Poliomyelitis, commonly shortened to polio, is an infectious disease caused by the poliovirus. Approximately 70% of cases are asymptomatic; mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe s ...
and
human papillomavirus Human papillomavirus infection (HPV infection) is caused by a DNA virus from the ''Papillomaviridae'' family. Many HPV infections cause no symptoms and 90% resolve spontaneously within two years. In some cases, an HPV infection persists and res ...
, though controversy later arose because the cells were being used without the knowledge of Lacks or her family. Jones's role in the Lacks case was described in the book '' The Immortal Life of Henrietta Lacks''. In 1960, the Joneses left private practice to join the Johns Hopkins faculty full-time. While there, Howard Jones participated in sex reassignment surgeries. In 1967, when sexual identity specialist
John Money John William Money (8 July 1921 – 7 July 2006) was a New Zealand psychologist, sexologist and author known for his research into sexual identity and Sex determination and differentiation (human), biology of gender. He was one of the first ...
recommended sex reassignment for a child named
David Reimer David Reimer (born Bruce Peter Reimer; 22 August 1965 – 4 May 2004) was a Canadian man born male but raised as a girl following medical advice and intervention after his penis was severely injured during a botched circumcision in infancy. ...
, Jones performed the surgery. Reimer, who had suffered a severe penile injury during a circumcision, was 22 months old when Jones removed his testicles, shaped his scrotal tissue to look like labia and repositioned his urethral opening. Money declared the procedure a success. The case became controversial when
Milton Diamond Milton Diamond (born March 6, 1934) is an American Professor Emeritus of anatomy and reproductive biology at the University of Hawaiʻi at Mānoa. After a career in the study of human sexuality, Diamond retired from the university in December 200 ...
published a 1997 follow-up study revealing Reimer experienced gender identity problems and lived as a man in adulthood. Reimer ultimately committed suicide at the age of 38. In the 1960s, he was able to participate in experiments involving sperm and
oocyte An oocyte (, ), oöcyte, or ovocyte is a female gametocyte or germ cell involved in reproduction. In other words, it is an immature ovum, or egg cell. An oocyte is produced in a female fetus in the ovary during female gametogenesis. The female ...
s with Robert Edwards, the doctor whose work later created the world's first test tube baby. In 1978, Jones faced
mandatory retirement Mandatory retirement also known as forced retirement, enforced retirement or compulsory retirement, is the set age at which people who hold certain jobs or offices are required by industry custom or by law to leave their employment, or retire. As ...
from Johns Hopkins. The Joneses moved to Virginia and established the Jones Institute for Reproductive Medicine at the
Eastern Virginia Medical School Eastern Virginia Medical School (EVMS) is a public medical school in Norfolk, Virginia. Founded by grassroots efforts in the Southeastern part of Virginia known as Hampton Roads, EVMS is not affiliated with an undergraduate institution and co ...
(EVMS). They created an
in vitro fertilization In vitro fertilisation (IVF) is a process of fertilisation where an egg is combined with sperm in vitro ("in glass"). The process involves monitoring and stimulating an individual's ovulatory process, removing an ovum or ova (egg or eggs) ...
(IVF) program at EVMS, which resulted in the 1981 birth of Elizabeth Jordan Carr, the first test tube baby in the country. Before his first successful IVF treatment, the clinic experienced 41 failed attempts at IVF. After his wife developed
Alzheimer's disease Alzheimer's disease (AD) is a neurodegeneration, neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in short-term me ...
in the late 1990s, Jones officially retired from his institute so that he could care for her. However, as of 2013, Jones still spent a few hours per day at EVMS and was writing his twelfth book. In February 2012, Jones successfully appealed to Virginia legislators to stop a bill that would have declared life to begin at conception. Jones said that the bill would have interfered with medical treatment for infertility. Jones has been recognized with a Distinguished Service Award from the
American Congress of Obstetricians and Gynecologists The American College of Obstetricians and Gynecologists (ACOG) is a professional association of physicians specializing in obstetrics and gynecology in the United States. Several Latin American countries are also represented within Districts of ...
. He was named a Fellow ad eundem of the
Royal College of Obstetricians and Gynaecologists The Royal College of Obstetricians and Gynaecologists (RCOG) is a professional association based in London, United Kingdom. Its members, including people with and without medical degrees, work in the field of obstetrics and gynaecology, that is ...
in 1986. Jones and his wife received Distinguished Alumnus Awards from
Johns Hopkins University Johns Hopkins University (Johns Hopkins, Hopkins, or JHU) is a private university, private research university in Baltimore, Maryland. Founded in 1876, Johns Hopkins is the oldest research university in the United States and in the western hem ...
in 1997.


Personal life

In 2011, Jones wrote an article for ''The Yale Journal for Humanities in Medicine'' on his keys to a long life. "First, I am the result of a tremendous shuffling of genetic material, which included some 3 billion potential variables. I got lucky. My combination seems to confer longevity," he said. He also wrote that his career and his family life had been enjoyable and rewarding, which had enhanced his longevity. Jones was married for 64 years before his wife's 2005 death. A son, Howard Jones, III, became the chairman of obstetrics and gynecology at
Vanderbilt University Medical Center The Vanderbilt University Medical Center (VUMC) is a medical provider with multiple hospitals in Nashville, Tennessee, as well as clinics and facilities throughout Middle Tennessee. VUMC is an independent non-profit organization, but maintains acad ...
in 2009. A daughter, Georgeanna Jones Klingensmith, is a pediatric endocrinologist in Denver.


Death

Jones died of respiratory failure on July 31, 2015 at the age of 104. He had been hospitalized at the Sentara Heart Hospital for the two weeks preceding his death.


Selected publications


Articles

* *


Books

* Jones, Howard W., Jr. (2015)
"Howard & Georgeanna".
Williamsburg, VA: Jamestowne Bookworks. * Jones, Howard W., Jr. (2014)
"In Vitro Fertilization Comes to America: Memoir of a Medical Breakthrough".
Williamsburg, VA: Jamestowne Bookworks. * Jones, Howard W., Jr. (2013)
''Personhood Revisited: Reproductive Technology, Bioethics, Religion and the Law''.
Minneapolis: Langdon Street Press. * Crockin, Susan L., and Jones, Howard W., Jr. (2010)
''Legal Conceptions: The Evolving Law and Policy of Assisted Reproductive Technologies''.
Baltimore:
Johns Hopkins University Press The Johns Hopkins University Press (also referred to as JHU Press or JHUP) is the publishing division of Johns Hopkins University. It was founded in 1878 and is the oldest continuously running university press in the United States. The press publi ...
.


References

{{DEFAULTSORT:Jones, Howard W. American gynecologists 1910 births 2015 deaths Amherst College alumni Eastern Virginia Medical School faculty Johns Hopkins School of Medicine alumni Johns Hopkins Hospital physicians American centenarians Men centenarians Surgeons specializing in transgender medicine