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David Reimer
David Reimer (born Bruce Peter Reimer; 22 August 1965 – 4 May 2004) was a Canadian man born male but raised as a girl following medical advice and intervention after his penis was severely injured during a botched circumcision in infancy. The psychologist John Money oversaw the case and reported the reassignment as successful and as evidence that gender identity is primarily learned. The academic sexologist Milton Diamond later reported that Reimer's realization that he was not a girl crystallized between the ages of 9 and 11 years and that he was living as a male by age 15. Well known in medical circles for years anonymously as the "John/Joan" case, Reimer later went public with his story to help discourage similar medical practices. At age 38, he committed suicide after suffering severe depression. Life Infancy David Reimer was born in Winnipeg, Manitoba, on 22 August 1965, the elder of identical twin boys. He was originally named Bruce, and his identical twin was named ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Winnipeg
Winnipeg () is the capital and largest city of the province of Manitoba in Canada. It is centred on the confluence of the Red and Assiniboine rivers, near the longitudinal centre of North America. , Winnipeg had a city population of 749,607 and a metropolitan population of 834,678, making it the sixth-largest city, and eighth-largest metropolitan area in Canada. The city is named after the nearby Lake Winnipeg; the name comes from the Western Cree words for "muddy water" - “winipīhk”. The region was a trading centre for Indigenous peoples long before the arrival of Europeans; it is the traditional territory of the Anishinabe (Ojibway), Ininew (Cree), Oji-Cree, Dene, and Dakota, and is the birthplace of the Métis Nation. French traders built the first fort on the site in 1738. A settlement was later founded by the Selkirk settlers of the Red River Colony in 1812, the nucleus of which was incorporated as the City of Winnipeg in 1873. Being far inland, the local ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
This Hour Has Seven Days
''This Hour Has Seven Days'' was a CBC Television news magazine that ran from 1964 to 1966, offering viewers in-depth analysis of the major social and political stories of the previous week. The show, inspired by the BBC and NBC-TV satire series ''That Was the Week That Was'', was created by Patrick Watson and Douglas Leiterman as an avenue for a more stimulating and boundary-pushing brand of television journalism. CBC executives believed the controversial show went beyond the limits of journalistic ethics and cancelled the show, leading to allegations of political interference. The show set new standards of broadcast journalism in Canada and the United States, and many of its elements inspired the tabloid talk show genre in later decades. Overview Hosts and contributors ''This Hour Has Seven Days'' was initially hosted by John Drainie, Laurier LaPierre, and Carole Simpson (not to be confused with the now-retired ABC weekend news anchor of the same name); Simpson wa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Estrogen
Estrogen or oestrogen is a category of sex hormone responsible for the development and regulation of the female reproductive system and secondary sex characteristics. There are three major endogenous estrogens that have estrogenic hormonal activity: estrone (E1), estradiol (E2), and estriol (E3). Estradiol, an estrane, is the most potent and prevalent. Another estrogen called estetrol (E4) is produced only during pregnancy. Estrogens are synthesized in all vertebrates and some insects. Their presence in both vertebrates and insects suggests that estrogenic sex hormones have an ancient evolutionary history. Quantitatively, estrogens circulate at lower levels than androgens in both men and women. While estrogen levels are significantly lower in males than in females, estrogens nevertheless have important physiological roles in males. Like all steroid hormones, estrogens readily diffuse across the cell membrane. Once inside the cell, they bind to and activate estrogen r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Suicide
Suicide is the act of intentionally causing one's own death. Mental disorders (including depression, bipolar disorder, schizophrenia, personality disorders, anxiety disorders), physical disorders (such as chronic fatigue syndrome), and substance abuse (including alcoholism and the use of and withdrawal from benzodiazepines) are risk factors. Some suicides are impulsive acts due to stress (such as from financial or academic difficulties), relationship problems (such as breakups or divorces), or harassment and bullying. Those who have previously attempted suicide are at a higher risk for future attempts. Effective suicide prevention efforts include limiting access to methods of suicide such as firearms, drugs, and poisons; treating mental disorders and substance abuse; careful media reporting about suicide; and improving economic conditions. Although crisis hotlines are common resources, their effectiveness has not been well studied. The most commonly adopted m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
John Colapinto
John Colapinto (born in 1958) is a Canadian journalist, author and novelist and a staff writer at ''The New Yorker''. In 2000, he wrote the ''New York Times'' bestseller '' As Nature Made Him: The Boy Who Was Raised as a Girl'', which exposed the details of the David Reimer case, a boy who had undergone a sex change in infancy—a medical experiment long heralded as a success, but which was, in fact, a failure. Career Before working on staff at ''The New Yorker'', Colapinto's articles appeared in '' Vanity Fair'', ''Esquire'', '' Mademoiselle'', '' Us'', ''New York'' and ''The New York Times Magazine'', and in 1995 he became a contributing editor at ''Rolling Stone''. Writing For ''Rolling Stone'', Colapinto wrote feature stories on a variety of subjects including AIDS, kids and guns, heroin in the music business, and ''Penthouse'' magazine creator, Bob Guccione. In 1998, Colapinto published a 20,000 word feature story in ''Rolling Stone'' titled "The True Story of John/Joan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sexual Differentiation
Sexual differentiation is the process of development of the sex differences between males and females from an undifferentiated zygote. Sex determination is often distinct from sex differentiation; sex determination is the designation for the development stage towards either male or female, while sex differentiation is the pathway towards the development of the phenotype. In many species, testicular or ovarian differentiation begins with appearance of Sertoli cells in males and granulosa cells in females. As male and female individuals develop from embryos into mature adults, sex differences at many levels develop, such as genes, chromosomes, gonads, hormones, anatomy, and psyche. Beginning with determination of sex by genetic and/or environmental factors, humans and other organisms proceed down different pathways of differentiation as they grow and develop. These processes are not fixed, and can change over one organism's lifetime or over many generations evolutionarily. S ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Scientific Control
A scientific control is an experiment or observation designed to minimize the effects of variables other than the independent variable (i.e. confounding variables). This increases the reliability of the results, often through a comparison between control measurements and the other measurements. Scientific controls are a part of the scientific method. Controlled experiments Controls eliminate alternate explanations of experimental results, especially experimental errors and experimenter bias. Many controls are specific to the type of experiment being performed, as in the molecular markers used in SDS-PAGE experiments, and may simply have the purpose of ensuring that the equipment is working properly. The selection and use of proper controls to ensure that experimental results are valid (for example, absence of confounding variables) can be very difficult. Control measurements may also be used for other purposes: for example, a measurement of a microphone's background noise ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gender Of Rearing
Sex assignment (sometimes known as gender assignment) is the discernment of an infant's sex at or before birth. A relative, midwife, nurse or physician inspects the external genitalia when the baby is delivered and, in more than 99.95% of births, sex is assigned without ambiguity. Assignment may also be done prior to birth through prenatal sex discernment. The sex assignment at or before birth usually aligns with a child's anatomical sex and phenotype. The number of births where the baby is intersex—where they do not fit into typical definitions of male and female at birth—has been reported to be as low as 0.018%, but is often estimated at around 0.2%. The number of births with ambiguous genitals is in the range of 0.02% to 0.05%. These conditions may complicate sex assignment. Other intersex conditions involve atypical chromosomes, gonads or hormones. Reinforcing sex assignments through surgical or hormonal interventions is often considered to violate the individual's hu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sex Assignment
Sex assignment (sometimes known as gender assignment) is the discernment of an infant's sex at or before birth. A relative, midwife, nurse or physician inspects the external genitalia when the baby is delivered and, in more than 99.95% of births, sex is assigned without ambiguity. Assignment may also be done prior to birth through prenatal sex discernment. The sex assignment at or before birth usually aligns with a child's anatomical sex and phenotype. The number of births where the baby is intersex—where they do not fit into typical definitions of male and female at birth—has been reported to be as low as 0.018%, but is often estimated at around 0.2%. The number of births with ambiguous genitals is in the range of 0.02% to 0.05%. These conditions may complicate sex assignment. Other intersex conditions involve atypical chromosomes, gonads or hormones. Reinforcing sex assignments through surgical or hormonal interventions is often considered to violate the individual's ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Testicle
A testicle or testis (plural testes) is the male reproductive gland or gonad in all bilaterians, including humans. It is homologous to the female ovary. The functions of the testes are to produce both sperm and androgens, primarily testosterone. Testosterone release is controlled by the anterior pituitary luteinizing hormone, whereas sperm production is controlled both by the anterior pituitary follicle-stimulating hormone and gonadal testosterone. Structure Appearance Males have two testicles of similar size contained within the scrotum, which is an extension of the abdominal wall. Scrotal asymmetry, in which one testicle extends farther down into the scrotum than the other, is common. This is because of the differences in the vasculature's anatomy. For 85% of men, the right testis hangs lower than the left one. Measurement and volume The volume of the testicle can be estimated by palpating it and comparing it to ellipsoids of known sizes. Another method is to use cal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Orchidectomy
Orchiectomy (also named orchidectomy, and sometimes shortened as orchi or orchie) is a surgical procedure in which one or both testicles are removed. The surgery is performed as treatment for testicular cancer, as part of surgery for transgender women, as management for advanced prostate cancer, and to remove damaged testes after testicular torsion. Less frequently, orchiectomy may be performed following a trauma, or due to wasting away of the testis or testes. Procedure Simple orchiectomy A simple orchiectomy is commonly performed as part of gender reassignment surgery for transgender women, or as palliative treatment for advanced cases of prostate cancer. A simple orchiectomy may also be required in the event of testicular torsion. For the procedure, the person lies flat on an operating table with the penis taped against the abdomen. The nurse shaves a small area for the incision. After anesthetic has been administered, the surgeon makes an incision in the midpoint of the s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sex Reassignment Surgery
Gender-affirming surgery (GAS) is a surgical procedure, or series of procedures, that alters a transgender or transsexual person's physical appearance and sexual characteristics to resemble those associated with their identified gender, and alleviate gender dysphoria. The term is also sometimes used to describe surgical intervention for intersex people. It is also known as sex reassignment surgery (SRS), gender confirmation surgery (GCS), and several other names. Professional medical organizations have established Standards of Care, which apply before someone can apply for and receive reassignment surgery, including psychological evaluation, and a period of real-life experience living in the desired gender. Feminization surgeries are surgeries that result in anatomy that is typically gendered female, such as vaginoplasty and breast augmentation, whereas masculinization surgeries are those that result in anatomy that is typically gendered male, such as phalloplasty and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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