Homem is a surname meaning "man" in Portuguese. Notable people with the surname include:
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Diogo Homem (1521–1576), Portuguese cartographer
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Guy-Manuel de Homem-Christo (born 1974), French musician, record producer, singer, songwriter, DJ, film director and composer
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Lopo Homem ( 1497– 1572), Portuguese cartographer
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Portuguese-language surnames