Holtzclaw is a surname. Notable people with the surname include:
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Bill Holtzclaw (born 1964), American politician
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Daniel Holtzclaw (born 1986), American former police officer and convicted serial rapist
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Henry J. Holtzclaw (1897–1969), United States Department of the Treasury official
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James Holtzclaw, American politician
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James T. Holtzclaw
James Thadeus Holtzclaw (December 17, 1833 – July 19, 1893) was an Alabama lawyer, railroad commissioner, and general in the Confederate States Army during the American Civil War. He played a prominent role of several major engagements of t ...
(1833–1893), American lawyer, railroad commissioner, and Confederate States Army general
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William Henry Holtzclaw
William Henry Holtzclaw (1870–1943) was an educator and the founder of Utica Institute in Mississippi. Holtzclaw was a graduate of the Tuskegee Institute and desired to start his own school. He settled in Utica, Mississippi, bought land on credit ...
, educator and founder of Utica Institute in Mississippi
{{surname, Holtzclaw