Hydroxyprostaglandin dehydrogenase 15-(NAD) (the
HUGO
Hugo or HUGO may refer to:
Arts and entertainment
* ''Hugo'' (film), a 2011 film directed by Martin Scorsese
* Hugo Award, a science fiction and fantasy award named after Hugo Gernsback
* Hugo (franchise), a children's media franchise based on ...
-approved official symbol = HPGD; HGNC ID, HGNC:5154), also called 15-hydroxyprostaglandin dehydrogenase
AD+ is an
enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
that in humans is encoded by the ''HPGD''
gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
.
In melanocytic cells HPGD gene expression may be regulated by
MITF
Microphthalmia-associated transcription factor also known as class E basic helix-loop-helix protein 32 or bHLHe32 is a protein that in humans is encoded by the ''MITF'' gene.
MITF is a basic helix-loop-helix leucine zipper transcription factor ...
.
See also
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Primary hypertrophic osteoathropathy
References
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