The HLA Informatics Group (HIG) is a research group led by Professor
Steven Marsh at the
Anthony Nolan Research Institute that develops, runs and maintains the IMGT (
immunogenetics)/HLA (
Human leukocyte antigen
The human leukocyte antigen (HLA) system or complex is a complex of genes on chromosome 6 in humans which encode cell-surface proteins responsible for the regulation of the immune system. The HLA system is also known as the human version of th ...
) Database and the IPD (immuno
polymorphism database). The IMGT/HLA database originated as part of
IMGT and was merged with IPD in 2003. The IMGT/HLA Database is a central repository for sequences of the human
major histocompatibility complex and currently contains over 5,000
allele
An allele (, ; ; modern formation from Greek ἄλλος ''állos'', "other") is a variation of the same sequence of nucleotides at the same place on a long DNA molecule, as described in leading textbooks on genetics and evolution.
::"The chro ...
sequences, including over 1,800
HLA-B
HLA-B (major histocompatibility complex, class I, B) is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen (HLA) compl ...
sequences.
As well as sequence information, the IMGT/HLA Database and the IPD Databases include extensive information regarding the source material that sequences are derived from.
About the Databases
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The IMGT/HLA website is the main source to know how many HLA alleles have been discovered.
References
External links
ANRI home page
HLA Informatics Group home page
IMGT/HLA database homepage
hla.alleles.org
IPD database homepage
Medical and health organisations based in the United Kingdom
Bioinformatics organizations
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