HLA-DR13(DR13) is a HLA- DR serotype that recognizes the DRB1*1301 to *13082, *1310 and some other *13 gene products. DR13 serotype is a split antigen of the older

HLA-DR6 HLA-DR6 (DR6) is a broad-antigen serotype that is further split into HLA-DR13 and HLA-DR14 antigen serotypes. Serology DR6 serological reactivity is relatively poor compared to other serological Serology is the scientific study of serum and o ...

serotype group which also contains the similar

HLA-DR14 HLA-DR14(DR14) is a HLA- DR serotype that recognizes the DRB1*1401 to *1408, *1410 to *1418, and other *14 gene products. DR14 serotype is a split antigen of the older HLA-DR6 serotype group which also contains the similar HLA-DR13 antigens. A ...

antigens.

Alleles

Serotypes are unknown the following alleles: DRB1*1309, *1315 to *1379 DRB1*13 allele group * 81 Alleles: 74 proteins * DR13 (weak or no DR6) Serotype: *1301, *1302, *1304, *1306, *1307, *1310, *1312 to *1314 * DR6 (weak DR13) Serotype: *1308 * DR13&Other serotypes: *1303, *1305, *1311, * Serotype unknown: *1309, *1315 to *1374

Disease associations

DRB1*1302 is linked to early childhood myastenia gravis. Alleles of DR13 along with immunization for hepatitis B and C are most protective against the disease.

Extended linkage

DRB1*1302:DQA1*0102:DQB1*0604 Early childhood myastenia gravis

Genetic Linkage

HLA-DR13 is genetically linked to DR52 and

HLA-DQ6 HLA-DQ6 (DQ6) is a human leukocyte antigen serotype within HLA-DQ (DQ) serotype group. The serotype is determined by the antibody recognition of β6 subset of DQ β-chains. The β-chain of DQ isoforms are encoded by HLA-DQB1 locus and DQ6 a ...

(

HLA-DQ1 HLA-DQ1 is a serotype that covers a broad range of HLA-DQ haplotypes. Historically it was identified as a DR-like alpha chain called DC1; later, it was among 3 types DQw1 (later DQ1, and split into DQ5 and DQ6), DQw2 and DQw3. Of these three ...

) serotypes.

References

{{DEFAULTSORT:Hla-Dr13 6